Mol Pharm -- Table of Contents (55 [1])

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January 1999; 55 (1)   [Index by Author] [Cover Caption]

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       Errata

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Articles:

Raymond W. Vazquez and Robert E. Oswald: Identification of a New Amino Acid Residue Capable of Modulating Agonist Efficacy at the Homomeric Nicotinic Acetylcholine Receptor, $alpha$ 7
Mol Pharmacol 1999 55: 1-7. [Abstract] [Full Text] [PDF]

Maoxing Shen and Stanley A. Thayer: $Delta$ ⁹-Tetrahydrocannabinol Acts as a Partial Agonist to Modulate Glutamatergic Synaptic Transmission between Rat Hippocampal Neurons in Culture
Mol Pharmacol 1999 55: 8-13. [Abstract] [Full Text] [PDF]

Satish C. Dogra, Benjamin P. Davidson, and Brian K. May: Analysis of a Phenobarbital-Responsive Enhancer Sequence Located in the 5' Flanking Region of the Chicken CYP2H1 Gene: Identification and Characterization of Functional Protein-Binding Sites
Mol Pharmacol 1999 55: 14-22. [Abstract] [Full Text] [PDF]

Daniel B. Campbell and Ellen J. Hess: L-Type Calcium Channels Contribute to the Tottering Mouse Dystonic Episodes
Mol Pharmacol 1999 55: 23-31. [Abstract] [Full Text] [PDF]

Tim Söderlund, Jukka Y. A. Lehtonen, and Paavo K. J. Kinnunen: Interactions of Cyclosporin A with Phospholipid Membranes: Effect of Cholesterol
Mol Pharmacol 1999 55: 32-38. [Abstract] [Full Text] [PDF]

Gary L. Aistrup, William Marszalec, and Toshio Narahashi: Ethanol Modulation of Nicotinic Acetylcholine Receptor Currents in Cultured Cortical Neurons
Mol Pharmacol 1999 55: 39-49. [Abstract] [Full Text] [PDF]

Dongmin Ma, Ping Wu, Robert W. Egan, M. Motasim Billah, and Peng Wang: Phosphodiesterase 4B Gene Transcription Is Activated by Lipopolysaccharide and Inhibited by Interleukin-10 in Human Monocytes
Mol Pharmacol 1999 55: 50-57. [Abstract] [Full Text] [PDF]

Kimberley Sabey, Ken Paradiso, Jessie Zhang, and Joe Henry Steinbach: Ligand Binding and Activation of Rat Nicotinic $alpha$ 4 $beta$ 2 Receptors Stably Expressed in HEK293 Cells
Mol Pharmacol 1999 55: 58-66. [Abstract] [Full Text] [PDF]

José A. Esté, Cecilia Cabrera, Erik De Clercq, Sofie Struyf, Jo Van Damme, Gary Bridger, Renato T. Skerlj, Michael J. Abrams, Geoffrey Henson, Arantxa Gutierrez, Bonaventura Clotet, and Dominique Schols: Activity of Different Bicyclam Derivatives against Human Immunodeficiency Virus Depends on Their Interaction with the CXCR4 Chemokine Receptor
Mol Pharmacol 1999 55: 67-73. [Abstract] [Full Text] [PDF]

Sylvie Colin, Jean-Claude Jeanny, Frederic Mascarelli, Raymond Vienet, Salman Al-Mahmood, Yves Courtois, and Jean Labarre: In Vivo Involvement of Heparan Sulfate Proteoglycan in the Bioavailability, Internalization, and Catabolism of Exogenous Basic Fibroblast Growth Factor
Mol Pharmacol 1999 55: 74-82. [Abstract] [Full Text] [PDF]

Weihua Xie, Cibby Varkey Altamirano, Cynthia F. Bartels, Robert J. Speirs, John R. Cashman, and Oksana Lockridge: An Improved Cocaine Hydrolase: The A328Y Mutant of Human Butyrylcholinesterase is 4-fold More Efficient
Mol Pharmacol 1999 55: 83-91. [Abstract] [Full Text] [PDF]

Jacky Marie, Caroline Koch, Didier Pruneau, Jean-Luc Paquet, Thierry Groblewski, Renée Larguier, Colette Lombard, Benoît Deslauriers, Bernard Maigret, and Jean-Claude Bonnafous: Constitutive Activation of the Human Bradykinin B₂ Receptor Induced by Mutations in Transmembrane Helices III and VI
Mol Pharmacol 1999 55: 92-101. [Abstract] [Full Text] [PDF]

Stuart A. Forman and Qing Zhou: Novel Modulation of a Nicotinic Receptor Channel Mutant Reveals that the Open State Is Stabilized by Ethanol
Mol Pharmacol 1999 55: 102-108. [Abstract] [Full Text] [PDF]

Mike D. Beecroft, Jonathan S. Marchant, Andrew M. Riley, Nicole C. R. Van Straten, Gijs A. Van der Marel, Jacques H. Van Boom, Barry V. L. Potter, and Colin W. Taylor: Acyclophostin: A Ribose-Modified Analog of Adenophostin A with High Affinity for Inositol 1,4,5-Trisphosphate Receptors and pH-Dependent Efficacy
Mol Pharmacol 1999 55: 109-117. [Abstract] [Full Text] [PDF]

Ali Bettaïeb, Isabelle Plo, Véronique Mansat-De Mas, Anne Quillet-Mary, Thierry Levade, Guy Laurent, and Jean-Pierre Jaffrézou: Daunorubicin- and Mitoxantrone-Triggered Phosphatidylcholine Hydrolysis: Implication in Drug-Induced Ceramide Generation and Apoptosis
Mol Pharmacol 1999 55: 118-125. [Abstract] [Full Text] [PDF]

Koichi Sato, Hideaki Tomura, Yasuyuki Igarashi, Michio Ui, and Fumikazu Okajima: Possible Involvement of Cell Surface Receptors in Sphingosine 1-Phosphate-Induced Activation of Extracellular Signal-Regulated Kinase in C6 Glioma Cells
Mol Pharmacol 1999 55: 126-133. [Abstract] [Full Text] [PDF]

Hong-Ling Li, Adriana Galue, Laurence Meadows, and David S. Ragsdale: A Molecular Basis for the Different Local Anesthetic Affinities of Resting Versus Open and Inactivated States of the Sodium Channel
Mol Pharmacol 1999 55: 134-141. [Abstract] [Full Text] [PDF]

Masuko Ushio-Fukai, R. Wayne Alexander, Marjorie Akers, P. Reid Lyons, Bernard Lassègue, and Kathy K. Griendling: Angiotensin II Receptor Coupling to Phospholipase D Is Mediated by the $beta$ $gamma$ Subunits of Heterotrimeric G Proteins in Vascular Smooth Muscle Cells
Mol Pharmacol 1999 55: 142-149. [Abstract] [Full Text] [PDF]

Zhiling Xiong, Cuneyt Bukusoglu, and Gary R. Strichartz: Local Anesthetics Inhibit the G Protein-Mediated Modulation of K⁺ and Ca⁺⁺ Currents in Anterior Pituitary Cells
Mol Pharmacol 1999 55: 150-158. [Abstract] [Full Text] [PDF]

Monica M. Lurtz and Steen E. Pedersen: Aminotriarylmethane Dyes Are High-Affinity Noncompetitive Antagonists of the Nicotinic Acetylcholine Receptor
Mol Pharmacol 1999 55: 159-167. [Abstract] [Full Text] [PDF]

Torben R. Neelands, Janet L. Fisher, Matt Bianchi, and Robert L. Macdonald: Spontaneous and $gamma$ -Aminobutyric Acid (GABA)-Activated GABA_A Receptor Channels Formed by $epsilon$ Subunit-Containing Isoforms
Mol Pharmacol 1999 55: 168-178. [Abstract] [Full Text] [PDF]

Henry S. Speno, Ruth Luthi-Carter, Wendy L. Macias, Stacey L. Valentine, Amit R. T. Joshi, and Joseph T. Coyle: Site-Directed Mutagenesis of Predicted Active Site Residues in Glutamate Carboxypeptidase II
Mol Pharmacol 1999 55: 179-185. [Abstract] [Full Text] [PDF]

Yuh-Chiang Shen, Chieh-Fu Chen, Sheng-Yuan Wang, and Yen-Jen Sung: Impediment to Calcium Influx and Reactive Oxygen Production Accounts for the Inhibition of Neutrophil Mac-1 Up-Regulation and Adhesion by Tetrandrine
Mol Pharmacol 1999 55: 186-193. [Abstract] [Full Text] [PDF]

Errata:

: Correction for vol. 53, p. 573
Mol Pharmacol 1999 55: 194. [Full Text] [PDF]

Cover Caption:

About the cover: Enhanced phospho-c-Jun immunostaining in SK-N-MC human neuroblastoma cells. Fifteen minutes after the additionof 100 µg of the D₁ dopamine receptor agonist SKF38393, cellswere fixed and incubated with anti-human phospho-c-Jun antibody,followed by flourescein-conjugated secondary antibody. Laser scanningconfocal microscopy was used to assess the distribution and relativeconcentration of phospho-c-Jun in cells. From Zhen X, Uryu K,Wang H-Y, Friedman E (1998) D₁ dopamine receptor agonists mediateactivation of p38 mitogen-activated protein kinase and c-Jun amino-terminalkinase by a protein kinase A-dependent mechanism in SK-N-MC humanneuroblastoma cells. Mol Pharmacol 54:453-458.