Mol Pharm -- Table of Contents (55 [2])

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February 1999; 55 (2)   [Index by Author] [Cover Caption]

       Accelerated Communication

       Articles

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Accelerated Communication:

Vicky N. Jackson, Daljit S. Bahia, and Graeme Milligan: Modulation of Relative Intrinsic Activity of Agonists at the Alpha-2A Adrenoceptor by Mutation of Residue 351 of G Protein G_i1
Mol Pharmacol 1999 55: 195-201. [Abstract] [Full Text] [PDF]

Articles:

Jow Y. Lew, Antonio Garcia-Espana, Kwan Y. Lee, Kenneth D. Carr, Menek Goldstein, John W. Haycock, and Emanuel Meller: Increased Site-Specific Phosphorylation of Tyrosine Hydroxylase Accompanies Stimulation of Enzymatic Activity Induced by Cessation of Dopamine Neuronal Activity
Mol Pharmacol 1999 55: 202-209. [Abstract] [Full Text] [PDF]

Stéphane Martin, Jean-Marie Botto, Jean-Pierre Vincent, and Jean Mazella: Pivotal Role of an Aspartate Residue in Sodium Sensitivity and Coupling to G Proteins of Neurotensin Receptors
Mol Pharmacol 1999 55: 210-215. [Abstract] [Full Text] [PDF]

Yin-Yuan Mo and William T. Beck: DNA Damage Signals Induction of Fas Ligand in Tumor Cells
Mol Pharmacol 1999 55: 216-222. [Abstract] [Full Text] [PDF]

Simon D. Lytton, Anders Helander, Zhi-Qi Zhang-Gouillon, Knut Stokkeland, Roberta Bordone, Sarino Aricò, Emanuele Albano, Samuel W. French, and Magnus Ingelman-Sundberg: Autoantibodies against Cytochromes P-4502E1 and P-4503A in Alcoholics
Mol Pharmacol 1999 55: 223-233. [Abstract] [Full Text] [PDF]

Juan Wang and Kathleen M. Giacomini: Characterization of a Bioengineered Chimeric Na⁺-Nucleoside Transporter
Mol Pharmacol 1999 55: 234-240. [Abstract] [Full Text] [PDF]

David J. Fraser, You Qun He, Greg R. Harlow, and James R. Halpert: Use of Chimeric Enzymes and Site-Directed Mutagenesis for Identification of Three Key Residues Responsible for Differences in Steroid Hydroxylation between Canine Cytochromes P-450 3A12 and 3A26
Mol Pharmacol 1999 55: 241-247. [Abstract] [Full Text] [PDF]

Carla V. Rothlin, Eleonora Katz, Miguel Verbitsky, and A. Belén Elgoyhen: The $alpha$ 9 Nicotinic Acetylcholine Receptor Shares Pharmacological Properties with Type A $gamma$ -Aminobutyric Acid, Glycine, and Type 3 Serotonin Receptors
Mol Pharmacol 1999 55: 248-254. [Abstract] [Full Text] [PDF]

C. C. Gerhardt, J. Gros, A. D. Strosberg, and T. Issad: Stimulation of the Extracellular Signal-Regulated Kinase 1/2 Pathway by Human Beta-3 Adrenergic Receptor: New Pharmacological Profile and Mechanism of Activation
Mol Pharmacol 1999 55: 255-262. [Abstract] [Full Text] [PDF]

Ronald Wolf, Thomas Koch, Stefan Schulz, Marcus Klutzny, Helmut Schröder, Evelyn Raulf, Frank Bühling, and Volker Höllt: Replacement of Threonine 394 by Alanine Facilitates Internalization and Resensitization of the Rat µ Opioid Receptor
Mol Pharmacol 1999 55: 263-268. [Abstract] [Full Text] [PDF]

Michael P. Blanton, Yu Xie, Lawrence J. Dangott, and Jonathan. B. Cohen: The Steroid Promegestone Is a Noncompetitive Antagonist of the Torpedo Nicotinic Acetylcholine Receptor that Interacts with the Lipid-Protein Interface
Mol Pharmacol 1999 55: 269-278. [Abstract] [Full Text] [PDF]

Kouichi Kurose, Masahiro Tohkin, and Morio Fukuhara: A Novel Positive Regulatory Element That Enhances Hamster CYP2A8 Gene Expression Mediated by Xenobiotic Responsive Element
Mol Pharmacol 1999 55: 279-287. [Abstract] [Full Text] [PDF]

Jianyong Chen, Jorge H. Capdevila, Darryl C. Zeldin, and Robert L. Rosenberg: Inhibition of Cardiac L-Type Calcium Channels by Epoxyeicosatrienoic Acids
Mol Pharmacol 1999 55: 288-295. [Abstract] [Full Text] [PDF]

Alf Berts, Hongying Zhong, and Kenneth P. Minneman: No Role for Ca⁺⁺ or Protein Kinase C in Alpha-1A Adrenergic Receptor Activation of Mitogen-Activated Protein Kinase Pathways in Transfected PC12 Cells
Mol Pharmacol 1999 55: 296-303. [Abstract] [Full Text] [PDF]

D. L. Feinstein, D. J. Reis, and S. Regunathan: Inhibition of Astroglial Nitric Oxide Synthase Type 2 Expression by Idazoxan
Mol Pharmacol 1999 55: 304-308. [Abstract] [Full Text] [PDF]

Hongzu Ren and Gary L. Stiles: Dexamethasone Stimulates Human A₁ Adenosine Receptor (A₁AR) Gene Expression through Multiple Regulatory Sites in Promoter B
Mol Pharmacol 1999 55: 309-316. [Abstract] [Full Text] [PDF]

Mario D. Galigniana, Graciela Piwien-Pilipuk, and Jamil Assreuy: Inhibition of Glucocorticoid Receptor Binding by Nitric Oxide
Mol Pharmacol 1999 55: 317-323. [Abstract] [Full Text] [PDF]

Catherine Mollereau, Lionel Mouledous, Sophie Lapalu, Gilles Cambois, Christiane Moisand, Jean-Luc Butour, and Jean-Claude Meunier: Distinct Mechanisms for Activation of the Opioid Receptor-Like 1 and $kappa$ -Opioid Receptors by Nociceptin and Dynorphin A
Mol Pharmacol 1999 55: 324-331. [Abstract] [Full Text] [PDF]

David W. Dawson, Olga V. Volpert, S. Frieda A. Pearce, Andrew J. Schneider, Roy L. Silverstein, Jack Henkin, and Noël P. Bouck: Three Distinct D-Amino Acid Substitutions Confer Potent Antiangiogenic Activity on an Inactive Peptide Derived from a Thrombospondin-1 Type 1 Repeat
Mol Pharmacol 1999 55: 332-338. [Abstract] [Full Text] [PDF]

Sakina Mhaouty-Kodja, Larry S. Barak, Alexander Scheer, Liliane Abuin, Dario Diviani, Marc G. Caron, and Susanna Cotecchia: Constitutively Active Alpha-1b Adrenergic Receptor Mutants Display Different Phosphorylation and Internalization Features
Mol Pharmacol 1999 55: 339-347. [Abstract] [Full Text] [PDF]

Stephen E. Ryan and John E. Baenziger: A Structure-Based Approach to Nicotinic Receptor Pharmacology
Mol Pharmacol 1999 55: 348-355. [Abstract] [Full Text] [PDF]

Hideki Tanaka, Nobuko Ohshima, and Hiroyoshi Hidaka: Isolation of cDNAs Encoding Cellular Drug-Binding Proteins Using a Novel Expression Cloning Procedure: Drug-Western
Mol Pharmacol 1999 55: 356-363. [Abstract] [Full Text] [PDF]

Lin Xu and John J. Enyeart: Purine and Pyrimidine Nucleotides Inhibit a Noninactivating K+ Current and Depolarize Adrenal Cortical Cells through a G Protein-Coupled Receptor
Mol Pharmacol 1999 55: 364-376. [Abstract] [Full Text] [PDF]

Christian Bailly, Xiaogang Qu, Fabrice Anizon, Michelle Prudhomme, Jean-François Riou, and Jonathan B. Chaires: Enhanced Binding to DNA and Topoisomerase I Inhibition by an Analog of the Antitumor Antibiotic Rebeccamycin Containing an Amino Sugar Residue
Mol Pharmacol 1999 55: 377-385. [Abstract] [Full Text] [PDF]

Andrew J. Moorhouse, Patrice Jacques, Peter H. Barry, and Peter R. Schofield: The Startle Disease Mutation Q266H, in the Second Transmembrane Domain of the Human Glycine Receptor, Impairs Channel Gating
Mol Pharmacol 1999 55: 386-395. [Abstract] [Full Text] [PDF]

Li Shen, Nicholas M. Dean, and Robert I. Glazer: Induction of p53-Dependent, Insulin-Like Growth Factor-Binding Protein-3-Mediated Apoptosis in Glioblastoma Multiforme Cells by a Protein Kinase C $alpha$ Antisense Oligonucleotide
Mol Pharmacol 1999 55: 396-402. [Abstract] [Full Text] [PDF]

Cover Caption:

About the cover: Enhanced phospho-c-Jun immunostaining in SK-N-MC human neuroblastoma cells. Fifteen minutes after the additionof 100 µg of the D₁ dopamine receptor agonist SKF38393, cellswere fixed and incubated with anti-human phospho-c-Jun antibody,followed by flourescein-conjugated secondary antibody. Laser scanningconfocal microscopy was used to assess the distribution and relativeconcentration of phospho-c-Jun in cells. From Zhen X, Uryu K,Wang H-Y, Friedman E (1998) D₁ dopamine receptor agonists mediateactivation of p38 mitogen-activated protein kinase and c-Jun amino-terminalkinase by a protein kinase A-dependent mechanism in SK-N-MC humanneuroblastoma cells. Mol Pharmacol 54:453-458.