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March 1999; 55 (3)   [Index by Author]  [Cover Caption]
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Articles:

Shi-Yong Sun, Ping Yue, and Reuben Lotan
Induction of Apoptosis by N-(4-Hydroxyphenyl)retinamide and Its Association with Reactive Oxygen Species, Nuclear Retinoic Acid Receptors, and Apoptosis-Related Genes in Human Prostate Carcinoma Cells
Mol Pharmacol 1999 55: 403-410. [Abstract] [Full Text] [PDF]  

Jahanshah Amin
A Single Hydrophobic Residue Confers Barbiturate Sensitivity to gamma -Aminobutyric Acid Type C Receptor
Mol Pharmacol 1999 55: 411-423. [Abstract] [Full Text] [PDF]  

M. Sorensen, M. Sehested, and P. B. Jensen
Effect of Cellular ATP Depletion on Topoisomerase II Poisons. Abrogation of Cleavable-Complex Formation by Etoposide But Not by Amsacrine
Mol Pharmacol 1999 55: 424-431. [Abstract] [Full Text] [PDF]  

Catherine P. Fenster, Matthew L. Beckman, Julie C. Parker, Elise B. Sheffield, Terri L. Whitworth, Michael W. Quick, and Robin A. J. Lester
Regulation of alpha 4beta 2 Nicotinic Receptor Desensitization by Calcium and Protein Kinase C
Mol Pharmacol 1999 55: 432-443. [Abstract] [Full Text] [PDF]  

Jaideep Kapur and Robert L. Macdonald
Postnatal Development of Hippocampal Dentate Granule Cell gamma -Aminobutyric AcidA Receptor Pharmacological Properties
Mol Pharmacol 1999 55: 444-452. [Abstract] [Full Text] [PDF]  

Stephane Litschig, Fabrizio Gasparini, Doris Rueegg, Natacha Stoehr, Peter Josef Flor, Ivo Vranesic, Laurent Prézeau, Jean-Philippe Pin, Christian Thomsen, and Rainer Kuhn
CPCCOEt, a Noncompetitive Metabotropic Glutamate Receptor 1 Antagonist, Inhibits Receptor Signaling Without Affecting Glutamate Binding
Mol Pharmacol 1999 55: 453-461. [Abstract] [Full Text] [PDF]  

Markus Klinger, Michael Freissmuth, Peter Nickel, Margit Stäbler-Schwarzbart, Matthias Kassack, Josef Suko, and Martin Hohenegger
Suramin and Suramin Analogs Activate Skeletal Muscle Ryanodine Receptor via a Calmodulin Binding Site
Mol Pharmacol 1999 55: 462-472. [Abstract] [Full Text] [PDF]  

Monsif Bouaboula, Nathalie Desnoyer, Pierre Carayon, Thérèse Combes, and Pierre Casellas
Gi Protein Modulation Induced by a Selective Inverse Agonist for the Peripheral Cannabinoid Receptor CB2: Implication for Intracellular Signalization Cross-Regulation.
Mol Pharmacol 1999 55: 473-480. [Abstract] [Full Text] [PDF]  

Ching-Chow Chen and Jia-Kae Wang
p38 but Not p44/42 Mitogen-Activated Protein Kinase Is Required for Nitric Oxide Synthase Induction Mediated by Lipopolysaccharide in RAW 264.7 Macrophages
Mol Pharmacol 1999 55: 481-488. [Abstract] [Full Text] [PDF]  

Suzanne L. Hansen, Bjarne Fjalland, and Meyer B. Jackson
Differential Blockade of gamma -Aminobutyric Acid Type A Receptors by the Neuroactive Steroid Dehydroepiandrosterone Sulfate in Posterior and Intermediate Pituitary
Mol Pharmacol 1999 55: 489-496. [Abstract] [Full Text] [PDF]  

Hong Shi, Huizhen Wang, and Zhiguo Wang
Identification and Characterization of Multiple Subtypes of Muscarinic Acetylcholine Receptors and Their Physiological Functions in Canine Hearts
Mol Pharmacol 1999 55: 497-507. [Abstract] [Full Text] [PDF]  

Marc R. D'Amours, Alexey E. Granovsky, Nikolai O. Artemyev, and Rick H. Cote
Potency and Mechanism of Action of E4021, a Type 5 Phosphodiesterase Isozyme-Selective Inhibitor, on the Photoreceptor Phosphodiesterase Depend on the State of Activation of the Enzyme
Mol Pharmacol 1999 55: 508-514. [Abstract] [Full Text] [PDF]  

William B. Parker, Sue C. Shaddix, Lucy M. Rose, Donna S. Shewach, Larry W. Hertel, John A. Secrist, III, John A. Montgomery, and L. Lee Bennett, Jr.
Comparison of the Mechanism of Cytotoxicity of 2-Chloro-9-(2-deoxy-2-fluoro-beta -D-arabinofuranosyl)adenine, 2-Chloro-9-(2-deoxy-2-fluoro-beta -D-ribofuranosyl)adenine, and 2-Chloro-9-(2-deoxy-2,2-difluoro-beta -D-ribofuranosyl)adenine in CEM Cells
Mol Pharmacol 1999 55: 515-520. [Abstract] [Full Text] [PDF]  

Jun-Feng Wang, Christopher Bown, and L. Trevor Young
Differential Display PCR Reveals Novel Targets for the Mood-Stabilizing Drug Valproate Including the Molecular Chaperone GRP78
Mol Pharmacol 1999 55: 521-527. [Abstract] [Full Text] [PDF]  

Paola Perego, Claudia Caserini, Laura Gatti, Nives Carenini, Simona Romanelli, Rosanna Supino, Donato Colangelo, Ilario Viano, Roberto Leone, Silvano Spinelli, Gabriella Pezzoni, Carla Manzotti, Nicholas Farrell, and Franco Zunino
A Novel Trinuclear Platinum Complex Overcomes Cisplatin Resistance in an Osteosarcoma Cell System
Mol Pharmacol 1999 55: 528-534. [Abstract] [Full Text] [PDF]  

Wen-Yi Gao, David G. Johns, Masatoshi Tanaka, and Hiroaki Mitsuya
Suppression of Replication of Multidrug-Resistant HIV Type 1 Variants by Combinations of Thymidylate Synthase Inhibitors with Zidovudine or Stavudine
Mol Pharmacol 1999 55: 535-540. [Abstract] [Full Text] [PDF]  

Herman G.P. Swarts, Harm P.H. Hermsen, Jan B. Koenderink, Peter H.G.M. Willems, and Jan Joep H.H.M. de Pont
Conformation-Dependent Inhibition of Gastric H+,K+-ATPase by SCH 28080 Demonstrated by Mutagenesis of Glutamic Acid 820
Mol Pharmacol 1999 55: 541-547. [Abstract] [Full Text] [PDF]  

Tayeb Khélifa and William T. Beck
Merbarone, a Catalytic Inhibitor of DNA Topoisomerase II, Induces Apoptosis in CEM Cells through Activation of ICE/CED-3-like Protease
Mol Pharmacol 1999 55: 548-556. [Abstract] [Full Text] [PDF]  

Liguang Lou, Tianhua Zhou, Ping Wang, and Gang Pei
Modulation of Ca2+/Calmodulin-Dependent Protein Kinase II Activity by Acute and Chronic Morphine Administration in Rat Hippocampus: Differential Regulation of alpha  and beta  Isoforms
Mol Pharmacol 1999 55: 557-563. [Abstract] [Full Text] [PDF]  

Adrian Newman-Tancredi, Didier Cussac, Valérie Audinot, Valérie Pasteau, Samantha Gavaudan, and Mark J. Millan
G Protein Activation by Human Dopamine D3 Receptors in High-Expressing Chinese Hamster Ovary Cells: A Guanosine-5'-O-(3-[35S]thio)-Triphosphate Binding and Antibody Study
Mol Pharmacol 1999 55: 564-574. [Abstract] [Full Text] [PDF]  

Arshad Rahman, Masashi Bando, John Kefer, Khandeker N. Anwar, and Asrar B. Malik
Protein Kinase C-Activated Oxidant Generation in Endothelial Cells Signals Intercellular Adhesion Molecule-1 Gene Transcription
Mol Pharmacol 1999 55: 575-583. [Abstract] [Full Text] [PDF]  

Daewoo Lee, Yoonseong Park, Thomas M. Brown, and Michael E. Adams
Altered Properties of Neuronal Sodium Channels Associated with Genetic Resistance to Pyrethroids
Mol Pharmacol 1999 55: 584-593. [Abstract] [Full Text] [PDF]  

Sakina E. Eltom, Leying Zhang, and Colin R. Jefcoate
Regulation of Cytochrome P-450 (CYP) 1B1 in Mouse Hepa-1 Variant Cell Lines: A Possible Role for Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) as a Suppressor of CYP1B1 Gene Expression
Mol Pharmacol 1999 55: 594-604. [Abstract] [Full Text] [PDF]  

Qing Tao, Sean D. McAllister, John Andreassi, Katharine W. Nowell, Guy A. Cabral, Dow P. Hurst, Kevin Bachtel, Marie C. Ekman, Patricia H. Reggio, and Mary E. Abood
Role of a Conserved Lysine Residue in the Peripheral Cannabinoid Receptor (CB2): Evidence for Subtype Specificity
Mol Pharmacol 1999 55: 605-613. [Abstract] [Full Text] [PDF]  

Masahiro Koshiba, Diane L. Rosin, Nobuhide Hayashi, Joel Linden, and Michail V.  Sitkovsky
Patterns of A2A Extracellular Adenosine Receptor Expression in Different Functional Subsets of Human Peripheral T Cells. Flow Cytometry Studies with Anti-A2A Receptor Monoclonal Antibodies
Mol Pharmacol 1999 55: 614-624. [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

About the cover: Enhanced phospho-c-Jun immunostaining in SK-N-MC human neuroblastoma cells. Fifteen minutes after the addition of 100 µg of the D1 dopamine receptor agonist SKF38393, cells were fixed and incubated with anti-human phospho-c-Jun antibody, followed by flourescein-conjugated secondary antibody. Laser scanning confocal microscopy was used to assess the distribution and relative concentration of phospho-c-Jun in cells. From Zhen X, Uryu K, Wang H-Y, Friedman E (1998) D1 dopamine receptor agonists mediate activation of p38 mitogen-activated protein kinase and c-Jun amino-terminal kinase by a protein kinase A-dependent mechanism in SK-N-MC human neuroblastoma cells. Mol Pharmacol 54:453-458.



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