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April 1999; 55 (4)   [Index by Author]  [Cover Caption]
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Minireview:

David L. DeWitt
Cox-2-Selective Inhibitors: The New Super Aspirins
Mol Pharmacol 1999 55: 625-631. [Full Text] [PDF]  

Articles:

Timothy D. Garver, Randall L. Kincaid, Richard A. Conn, and Melvin L. Billingsley
Reduction of Calcineurin Activity in Brain by Antisense Oligonucleotides Leads to Persistent Phosphorylation of tau  Protein at Thr181 and Thr231
Mol Pharmacol 1999 55: 632-641. [Abstract] [Full Text] [PDF]  

Lance G. Hammerland, Karen J. Krapcho, James E. Garrett, Nousheen Alasti, Benjamin C. P. Hung, Rachel T. Simin, Cynthia Levinthal, Edward F. Nemeth, and Forrest H. Fuller
Domains Determining Ligand Specificity for Ca2+ Receptors
Mol Pharmacol 1999 55: 642-648. [Abstract] [Full Text] [PDF]  

K. C. Falkner, G.-H. Xiao, J. A. Pinaire, M. L. Pendleton, R. Lindahl, and R. A. Prough
The Negative Regulation of the Rat Aldehyde Dehydrogenase 3 Gene by Glucocorticoids: Involvement of a Single Imperfect Palindromic Glucocorticoid Responsive Element
Mol Pharmacol 1999 55: 649-657. [Abstract] [Full Text] [PDF]  

Shu Fang Liu, Xiaobing Ye, and Asrar B. Malik
Pyrrolidine Dithiocarbamate Prevents I-kappa B Degradation and Reduces Microvascular Injury Induced by Lipopolysaccharide in Multiple Organs
Mol Pharmacol 1999 55: 658-667. [Abstract] [Full Text] [PDF]  

Morito Sakaue, Hiroshi Adachi, and Anton M. Jetten
Post-Transcriptional Regulation of MyD118 and GADD45 in Human Lung Carcinoma Cells During 6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalene Carboxylic Acid-Induced Apoptosis
Mol Pharmacol 1999 55: 668-676. [Abstract] [Full Text] [PDF]  

Qin Fu, Seung-Whan Kim, Hong-Xin Chen, Susan Grill, and Yung-Chi Cheng
Degradation of Topoisomerase I Induced by Topoisomerase I Inhibitors Is Dependent on Inhibitor Structure but Independent of Cell Death
Mol Pharmacol 1999 55: 677-683. [Abstract] [Full Text] [PDF]  

Nathalie Macrez, Jean-Luc Morel, and Jean Mironneau
Specific Galpha 11beta 3gamma 5 Protein Involvement in Endothelin Receptor-Induced Phosphatidylinositol Hydrolysis and Ca2+ Release in Rat Portal Vein Myocytes
Mol Pharmacol 1999 55: 684-692. [Abstract] [Full Text] [PDF]  

Leena Alhonen, Marko Pietilä, Maria Halmekytö, Debora L. Kramer, Juhani Jänne, and Carl W. Porter
Transgenic Mice with Activated Polyamine Catabolism due to Overexpression of Spermidine/Spermine N1-Acetyltransferase Show Enhanced Sensitivity to the Polyamine Analog, N1,N11-Diethylnorspermine
Mol Pharmacol 1999 55: 693-698. [Abstract] [Full Text] [PDF]  

Serenella Albani-Torregrossa, Sabina Attucci, Maura Marinozzi, Roberto Pellicciari, Flavio Moroni, and Domenico E. Pellegrini-Giampietro
Antagonist Pharmacology of Metabotropic Glutamate Receptors Coupled to Phospholipase D Activation in Adult Rat Hippocampus: Focus on (2R,1'S,2'R,3'S)-2-(2'-Carboxy-3'-phenylcyclopropyl)glycine Versus 3,5-Dihydroxyphenylglycine
Mol Pharmacol 1999 55: 699-707. [Abstract] [Full Text] [PDF]  

Gavin E. Arteel, Maria B. Kadiiska, Ivan Rusyn, Blair U. Bradford, Ronald P. Mason, James A. Raleigh, and Ronald G. Thurman
Oxidative Stress Occurs in Perfused Rat Liver at Low Oxygen Tension by Mechanisms Involving Peroxynitrite
Mol Pharmacol 1999 55: 708-715. [Abstract] [Full Text] [PDF]  

Ellen C. Henry, Andrew S. Kende, George Rucci, Michael J. Totleben, J. Jeffrey Willey, Stephen D. Dertinger, Richard S. Pollenz, Jeffrey P. Jones, and Thomas A. Gasiewicz
Flavone Antagonists Bind Competitively with 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) to the Aryl Hydrocarbon Receptor But Inhibit Nuclear Uptake and Transformation
Mol Pharmacol 1999 55: 716-725. [Abstract] [Full Text] [PDF]  

Igor Feoktistov, Anna E. Goldstein, and Italo Biaggioni
Role of p38 Mitogen-Activated Protein Kinase and Extracellular Signal-Regulated Protein Kinase Kinase in Adenosine A2B Receptor-Mediated Interleukin-8 Production in Human Mast Cells
Mol Pharmacol 1999 55: 726-734. [Abstract] [Full Text] [PDF]  

Katsumi Fujimoto, Kazumi Ohta, Kenji Kangawa, Ushio Kikkawa, Satoshi Ogino, and Hiroyuki Fukui
Identification of Protein Kinase C Phosphorylation Sites Involved in Phorbol Ester-Induced Desensitization of the Histamine H1 Receptor
Mol Pharmacol 1999 55: 735-742. [Abstract] [Full Text] [PDF]  

Satohiro Masuda, Koji Ibaramoto, Ayako Takeuchi, Hideyuki Saito, Yukiya Hashimoto, and Ken-Ichi Inui
Cloning and Functional Characterization of a New Multispecific Organic Anion Transporter, OAT-K2, in Rat Kidney
Mol Pharmacol 1999 55: 743-752. [Abstract] [Full Text] [PDF]  

Alberto Fernández de Arriba, Fernando Cavalcanti, Agustí Miralles, Yolanda Bayón, Andrés Alonso, Manuel Merlos, Julián García-Rafanell, and Javier Forn
Inhibition of Cyclooxygenase-2 Expression by 4-Trifluoromethyl Derivatives of Salicylate, Triflusal, and Its Deacetylated Metabolite, 2-Hydroxy-4-trifluoromethylbenzoic Acid
Mol Pharmacol 1999 55: 753-760. [Abstract] [Full Text] [PDF]  

Gerrit Jansen, Haim Barr, Ietje Kathmann, Marlene A. Bunni, David G. Priest, Paul Noordhuis, Godefridus J. Peters, and Yehuda G. Assaraf
Multiple Mechanisms of Resistance to Polyglutamatable and Lipophilic Antifolates in Mammalian Cells: Role of Increased Folylpolyglutamylation, Expanded Folate Pools, and Intralysosomal Drug Sequestration
Mol Pharmacol 1999 55: 761-769. [Abstract] [Full Text] [PDF]  

Víctor M. González, Miguel A. Fuertes, Antonio Jiménez-Ruíz, Carlos Alonso, and José M. Pérez
The Formation of DNA Interstrand Cross-Links by a Novel Bis-[Pt2Cl4(diminazene aceturate)2]Cl4·4H2O Complex Inhibits the B to Z Transition
Mol Pharmacol 1999 55: 770-777. [Abstract] [Full Text] [PDF]  

Nigel J. M. Birdsall, Tim Farries, Parviz Gharagozloo, Shinsaku Kobayashi, Sebastian Lazareno, and Masahiko Sugimoto
Subtype-Selective Positive Cooperative Interactions Between Brucine Analogs and Acetylcholine at Muscarinic Receptors: Functional Studies
Mol Pharmacol 1999 55: 778-786. [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

About the cover: Enhanced phospho-c-Jun immunostaining in SK-N-MC human neuroblastoma cells. Fifteen minutes after the addition of 100 µg of the D1 dopamine receptor agonist SKF38393, cells were fixed and incubated with anti-human phospho-c-Jun antibody, followed by flourescein-conjugated secondary antibody. Laser scanning confocal microscopy was used to assess the distribution and relative concentration of phospho-c-Jun in cells. From Zhen X, Uryu K, Wang H-Y, Friedman E (1998) D1 dopamine receptor agonists mediate activation of p38 mitogen-activated protein kinase and c-Jun amino-terminal kinase by a protein kinase A-dependent mechanism in SK-N-MC human neuroblastoma cells. Mol Pharmacol 54:453-458.



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