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Other Issues:
September 1999; 56 (3)   [Index by Author]  [Cover Caption]
       Accelerated Communication
       Articles
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Accelerated Communication:

Qing Yang and Stephen M. Lanier
ACCELERATED COMMUNICATION: Influence of G Protein Type on Agonist Efficacy
Mol Pharmacol 1999 56: 651-656. [Abstract] [Full Text] [PDF]  

Henry M. Sarau, Robert S. Ames, Jon Chambers, Catherine Ellis, Nabil Elshourbagy, James J. Foley, Dulcie B. Schmidt, Roseanna M. Muccitelli, Owen Jenkins, Paul R. Murdock, Nicole C. Herrity, Wendy Halsey, Ganesh Sathe, Alison I. Muir, Parvathi Nuthulaganti, George M. Dytko, Peter T. Buckley, Shelagh Wilson, Derk J. Bergsma, and Douglas W.P. Hay
ACCELERATED COMMUNICATION: Identification, Molecular Cloning, Expression, and Characterization of a Cysteinyl Leukotriene Receptor
Mol Pharmacol 1999 56: 657-663. [Abstract] [Full Text] [PDF]  

Articles:

Zhi Zhong, Henry D. Connor, Ming Yin, Nicholas Moss, Ronald P. Mason, Hartwig Bunzendahl, Donald T. Forman, and Ronald G. Thurman
Dietary Glycine and Renal Denervation Prevents Cyclosporin A-Induced Hydroxyl Radical Production in Rat Kidney
Mol Pharmacol 1999 56: 455-463. [Abstract] [Full Text] [PDF]  

Volker Schmieden, Jochen Kuhse, and Heinrich Betz
A Novel Domain of the Inhibitory Glycine Receptor Determining Antagonist Efficacies: Further Evidence for Partial Agonism Resulting from Self-Inhibition
Mol Pharmacol 1999 56: 464-472. [Abstract] [Full Text] [PDF]  

Tatsuya Sueyoshi, Norihiko Yokomori, Kenneth S. Korach, and Masahiko Negishi
Developmental Action of Estrogen Receptor-alpha Feminizes the Growth Hormone-Stat5b Pathway and Expression of Cyp2a4 and Cyp2d9 Genes in Mouse Liver
Mol Pharmacol 1999 56: 473-477. [Abstract] [Full Text] [PDF]  

Wilberto Nieves-Neira, Maria I. Rivera, Glenda Kohlhagen, Miriam L. Hursey, Philippe Pourquier, Edward A. Sausville, and Yves Pommier
DNA Protein Cross-Links Produced by NSC 652287, a Novel Thiophene Derivative Active Against Human Renal Cancer Cells
Mol Pharmacol 1999 56: 478-484. [Abstract] [Full Text] [PDF]  

Ying-Ying Zhou, Heping Cheng, Long-Sheng Song, Dingji Wang, Edward G. Lakatta, and Rui-Ping Xiao
Spontaneous beta 2-Adrenergic Signaling Fails To Modulate L-Type Ca2+ Current in Mouse Ventricular Myocytes
Mol Pharmacol 1999 56: 485-493. [Abstract] [Full Text] [PDF]  

Valerian E. Kagan, Jack C. Yalowich, Grigory G. Borisenko, Yulia Y. Tyurina, Vladimir A. Tyurin, Padmakumari Thampatty, and James P. Fabisiak
Mechanism-Based Chemopreventive Strategies Against Etoposide-Induced Acute Myeloid Leukemia: Free Radical/Antioxidant Approach
Mol Pharmacol 1999 56: 494-506. [Abstract] [Full Text] [PDF]  

Chang-Shin Park, Hyun-Moon Baek, Woon-Gye Chung, Kyung-Hoon Lee, Seung-Duk Ryu, and Young-Nam Cha
Suppression of Flavin-Containing Monooxygenase by Overproduced Nitric Oxide in Rat Liver
Mol Pharmacol 1999 56: 507-514. [Abstract] [Full Text] [PDF]  

Deepika Rajesh, Kathleen Schell, and A. K. Verma
Ras Mutation, Irrespective of Cell Type and p53 Status, Determines a Cell's Destiny to Undergo Apoptosis by Okadaic Acid, an Inhibitor of Protein Phosphatase 1 and 2A
Mol Pharmacol 1999 56: 515-525. [Abstract] [Full Text] [PDF]  

Pascal Bernard, Hervé Goudonnet, Yves Artur, Béatrice Desvergne, and Walter Wahli
Activation of the Mouse TATA-less and Human TATA-Containing UDP-Glucuronosyltransferase 1A1 Promoters by Hepatocyte Nuclear Factor 1
Mol Pharmacol 1999 56: 526-536. [Abstract] [Full Text] [PDF]  

Barbara F. Hales
Post-Translational Regulation of AP-1 Transcription Factor DNA-Binding Activity in the Rat Conceptus
Mol Pharmacol 1999 56: 537-544. [Abstract] [Full Text] [PDF]  

Brett A. Stillman, Matthew D. Breyer, and Richard M. Breyer
Importance of the Extracellular Domain for Prostaglandin EP2 Receptor Function
Mol Pharmacol 1999 56: 545-551. [Abstract] [Full Text] [PDF]  

Vincent Contesse, Sebastien Lenglet, Luca Grumolato, Youssef Anouar, Isabelle Lihrmann, Herve Lefebvre, Catherine Delarue, and Hubert Vaudry
Pharmacological and Molecular Characterization of 5-Hydroxytryptamine7 Receptors in the Rat Adrenal Gland
Mol Pharmacol 1999 56: 552-561. [Abstract] [Full Text] [PDF]  

An R. Van Rompay, Magnus Johansson, and Anna Karlsson
Phosphorylation of Deoxycytidine Analog Monophosphates by UMP-CMP Kinase: Molecular Characterization of the Human Enzyme
Mol Pharmacol 1999 56: 562-569. [Abstract] [Full Text] [PDF]  

Tomas Cihlar, Deborah C. Lin, John B. Pritchard, Michael D. Fuller, Dirk B. Mendel, and Douglas H. Sweet
The Antiviral Nucleotide Analogs Cidofovir and Adefovir Are Novel Substrates for Human and Rat Renal Organic Anion Transporter 1
Mol Pharmacol 1999 56: 570-580. [Abstract] [Full Text] [PDF]  

Arpad Szallasi, Peter M. Blumberg, Lauren L. Annicelli, James E. Krause, and Daniel N. Cortright
The Cloned Rat Vanilloid Receptor VR1 Mediates Both R-Type Binding and C-Type Calcium Response in Dorsal Root Ganglion Neurons
Mol Pharmacol 1999 56: 581-587. [Abstract] [Full Text] [PDF]  

Jennifer J. Schlezinger, Renee D. White, and John J. Stegeman
Oxidative Inactivation of Cytochrome P-450 1A (CYP1A) Stimulated by 3,3',4,4'-Tetrachlorobiphenyl: Production of Reactive Oxygen by Vertebrate CYP1As
Mol Pharmacol 1999 56: 588-597. [Abstract] [Full Text] [PDF]  

Torben R. Neelands and Robert L. Macdonald
Incorporation of the pi  Subunit into Functional gamma -Aminobutyric AcidA Receptors
Mol Pharmacol 1999 56: 598-610. [Abstract] [Full Text] [PDF]  

John P. Roche, Sid Bounds, Sean Brown, and Ken Mackie
A Mutation in the Second Transmembrane Region of the CB1 Receptor Selectively Disrupts G Protein Signaling and Prevents Receptor Internalization
Mol Pharmacol 1999 56: 611-618. [Abstract] [Full Text] [PDF]  

Lech Kiedrowski
N-methyl-D-aspartate Excitotoxicity: Relationships among Plasma Membrane Potential, Na+/Ca2+ Exchange, Mitochondrial Ca2+ Overload, and Cytoplasmic Concentrations of Ca2+, H+, and K+
Mol Pharmacol 1999 56: 619-632. [Abstract] [Full Text] [PDF]  

Eric D. Scheeff, James M. Briggs, and Stephen B. Howell
Molecular Modeling of the Intrastrand Guanine-Guanine DNA Adducts Produced by Cisplatin and Oxaliplatin
Mol Pharmacol 1999 56: 633-643. [Abstract] [Full Text] [PDF]  

Hsing-Lin Lai, Ting-Hui Lin, Yu-Ya Kao, Wu-Ja Lin, Ming-Jing Hwang, and Yijuang Chern
The N Terminus Domain of Type VI Adenylyl Cyclase Mediates Its Inhibition by Protein Kinase C
Mol Pharmacol 1999 56: 644-650. [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

About the cover: Putative structure of a regulatory domain in the amino terminus of the N-methyl-D-aspartate (NMDA) receptor NR1 subunit. The left-hand schematic shows the proposed topology of the NMDA receptor subunits with three membrane-spanning domains, a re-entrant loop, the agonist binding pocket formed by the S1-S2 domains (with the agonist shown by a gray oval), and a large extracellular amino terminus that precedes S1. The positions of amino acid residues that may form binding sites for ifenprodil (green) and spermine (yellow) are shown by circles. The right-hand schematic is a projected structure of the bacterial leucine/isoleucine/valine binding protein (LIVBP). The putative secondary structure of the amino terminus of NR1 shows considerable similarity to that of LIVBP, and this region of NR1, which is termed the R1-R2 regulatory domain, is proposed to have a tertiary structure similar to LIVBP. From Masuko T, Kashiwagi K, Kuno T, Nguyen ND, Pahk AJ, Fukuchi J-I, Igarashi K and Williams K (1999) A regulatory domain (R1-R2) in the amino terminus of the N-methyl-D-aspartate receptor: Effects of spermine, protons, and ifenprodil, and structural similarity to bacterial LIVBP. Mol Pharmacol 55:957-969.



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