Perspective:

Lindsay B. Hough

Genomics Meets Histamine Receptors: New Subtypes, New Receptors
Mol Pharmacol 2001 59: 415-419. [Full Text] [PDF]  

Minireview:

Robert H. Tukey and Christian P. Strassburg

Genetic Multiplicity of the Human UDP-Glucuronosyltransferases and Regulation in the Gastrointestinal Tract
Mol Pharmacol 2001 59: 405-414. [Abstract] [Full Text] [PDF]  

Accelerated Communication:

Changlu Liu, Xiao-Jun Ma, Xiaoxia Jiang, Sandy J. Wilson, Claudia L. Hofstra, Jonathan Blevitt, Jayashree Pyati, Xiaobing Li, Wenying Chai, Nicholas Carruthers, and Timothy W. Lovenberg

Cloning and Pharmacological Characterization of a Fourth Histamine Receptor (H₄) Expressed in Bone Marrow
Mol Pharmacol 2001 59: 420-426. [Abstract] [Full Text] [PDF]  

Tuan Nguyen, David A. Shapiro, Susan R. George, Vincent Setola, Dennis K. Lee, Regina Cheng, Laura Rauser, Samuel P. Lee, Kevin R. Lynch, Bryan L. Roth, and Brian F. O'Dowd

Discovery of a Novel Member of the Histamine Receptor Family
Mol Pharmacol 2001 59: 427-433. [Abstract] [Full Text] [PDF]  

Yuan Zhu, David Michalovich, Hsiao-Ling Wu, K. B. Tan, George M. Dytko, Ishrat J. Mannan, Rogely Boyce, James Alston, Lauren A Tierney, Xiaotong Li, Nicole C. Herrity, Lisa Vawter, Henry M. Sarau, Robert S. Ames, Colleen M. Davenport, J. Paul Hieble, Shelagh Wilson, Derk J. Bergsma, and Laura R. Fitzgerald

Cloning, Expression, and Pharmacological Characterization of a Novel Human Histamine Receptor
Mol Pharmacol 2001 59: 434-441. [Abstract] [Full Text] [PDF]  

Florence Crestani, Karin Löw, Ruth Keist, Marie-Juliette Mandelli, Hanns Möhler, and Uwe Rudolph

Molecular Targets for the Myorelaxant Action of Diazepam
Mol Pharmacol 2001 59: 442-445. [Abstract] [Full Text] [PDF]  

Articles:

Qing Li, Christopher Boyer, Jean Y. Lee, and H. Michael Shepard

A Novel Approach to Thymidylate Synthase as a Target for Cancer Chemotherapy
Mol Pharmacol 2001 59: 446-452. [Abstract] [Full Text] [PDF]  

Brian B. Hasinoff, Michael E. Abram, Norman Barnabé, Tayeb Khélifa, William P. Allan, and Jack C. Yalowich

The Catalytic DNA Topoisomerase II Inhibitor Dexrazoxane (ICRF-187) Induces Differentiation and Apoptosis in Human Leukemia K562 Cells
Mol Pharmacol 2001 59: 453-461. [Abstract] [Full Text] [PDF]  

Ruoli Bai, Pascal Verdier-Pinard, Sanjeev Gangwar, Chad C. Stessman, Kelly J. McClure, Edward A. Sausville, George R. Pettit, Robert B. Bates, and Ernest Hamel

Dolastatin 11, a Marine Depsipeptide, Arrests Cells at Cytokinesis and Induces Hyperpolymerization of Purified Actin
Mol Pharmacol 2001 59: 462-469. [Abstract] [Full Text] [PDF]  

Takemitsu Furuchi, Hirohide Ishikawa, Nobuhiko Miura, Miki Ishizuka, Kazuki Kajiya, Shusuke Kuge, and Akira Naganuma

Two Nuclear Proteins, Cin5 and Ydr259c, Confer Resistance to Cisplatin in Saccharomyces cerevisiae
Mol Pharmacol 2001 59: 470-474. [Abstract] [Full Text] [PDF]  

Margit Spatzenegger, Qinmi Wang, You Qun He, Michael R. Wester, Eric F. Johnson, and James R. Halpert

Amino Acid Residues Critical for Differential Inhibition of CYP2B4, CYP2B5, and CYP2B1 by Phenylimidazoles
Mol Pharmacol 2001 59: 475-484. [Abstract] [Full Text] [PDF]  

Guoheng Xu, Cristina Rabadan-Diehl, Maria Nikodemova, Peter Wynn, Joachim Spiess, and Greti Aguilera

Inhibition of Corticotropin Releasing Hormone Type-1 Receptor Translation by an Upstream AUG Triplet in the 5' Untranslated Region
Mol Pharmacol 2001 59: 485-492. [Abstract] [Full Text] [PDF]  

Ching-Chow Chen, Yi-Tao Sun, Jun-Jie Chen, and Ya-Jen Chang

Tumor Necrosis Factor--Induced Cyclooxygenase-2 Expression via Sequential Activation of Ceramide-Dependent Mitogen-Activated Protein Kinases, and IB Kinase 1/2 in Human Alveolar Epithelial Cells
Mol Pharmacol 2001 59: 493-500. [Abstract] [Full Text] [PDF]  

Akio Kanatani, Mikiko Hata, Satoshi Mashiko, Akane Ishihara, Osamu Okamoto, Yuji Haga, Tomoyuki Ohe, Tetsuya Kanno, Naomi Murai, Yasuyuki Ishii, Takahiro Fukuroda, Takehiro Fukami, and Masaki Ihara

A Typical Y1 Receptor Regulates Feeding Behaviors: Effects of a Potent and Selective Y1 Antagonist, J-115814
Mol Pharmacol 2001 59: 501-505. [Abstract] [Full Text] [PDF]  

Isaac N. Pessah, Chris Beltzner, Scott W. Burchiel, Gopishetty Sridhar, Trevor Penning, and Wei Feng

A Bioactive Metabolite of Benzo[a]pyrene, Benzo[a]pyrene-7,8-dione, Selectively Alters Microsomal Ca²⁺ Transport and Ryanodine Receptor Function
Mol Pharmacol 2001 59: 506-513. [Abstract] [Full Text] [PDF]  

Erika M. Adkins, Eric L. Barker, and Randy D. Blakely

Interactions of Tryptamine Derivatives with Serotonin Transporter Species Variants Implicate Transmembrane Domain I in Substrate Recognition
Mol Pharmacol 2001 59: 514-523. [Abstract] [Full Text] [PDF]  

Takahiro Iwamoto, Satomi Kita, Akira Uehara, Yutaka Inoue, Yuki Taniguchi, Issei Imanaga, and Munekazu Shigekawa

Structural Domains Influencing Sensitivity to Isothiourea Derivative Inhibitor KB-R7943 in Cardiac Na⁺/Ca²⁺ Exchanger
Mol Pharmacol 2001 59: 524-531. [Abstract] [Full Text] [PDF]  

Susan M. Wade, Keng-Li Lan, Dorian J. Moore, and Richard R. Neubig

Inverse Agonist Activity at the _2A-Adrenergic Receptor
Mol Pharmacol 2001 59: 532-542. [Abstract] [Full Text] [PDF]  

Josef Suko, Gertrude Hellmann, and Helmut Drobny

Short- and Long-Term Functional Alterations of the Skeletal Muscle Calcium Release Channel (Ryanodine Receptor) by Suramin: Apparent Dissociation of Single Channel Current Recording and [³H]Ryanodine Binding
Mol Pharmacol 2001 59: 543-556. [Abstract] [Full Text] [PDF]  

Steven L. Levine and Gary H. Perdew

Aryl Hydrocarbon Receptor (AhR)/AhR Nuclear Translocator (ARNT) Activity Is Unaltered by Phosphorylation of a Periodicity/ARNT/Single-Minded (PAS)-Region Serine Residue
Mol Pharmacol 2001 59: 557-566. [Abstract] [Full Text] [PDF]  

Tatjana Albrektsen and Jan Fleckner

The Transcription Factor Fos-Related Antigen 1 Is Induced by Thiazolidinediones During Differentiation of 3T3-L1 Cells
Mol Pharmacol 2001 59: 567-575. [Abstract] [Full Text] [PDF]  

Agustín García-Caballero, J. Alberto Olivares-Reyes, Kevin J. Catt, and J. Adolfo García-Saínz

Angiotensin AT₁ Receptor Phosphorylation and Desensitization in a Hepatic Cell Line. Roles of Protein Kinase C and Phosphoinositide 3-Kinase
Mol Pharmacol 2001 59: 576-585. [Abstract] [Full Text] [PDF]  

Harry P. De Koning

Uptake of Pentamidine in Trypanosoma brucei brucei is Mediated by Three Distinct Transporters: Implications for Cross-Resistance with Arsenicals
Mol Pharmacol 2001 59: 586-592. [Abstract] [Full Text] [PDF]  

Yi-He Ling, Yun Zhong, and Roman Perez-Soler

Disruption of Cell Adhesion and Caspase-Mediated Proteolysis of - and -Catenins and APC Protein in Paclitaxel-Induced Apoptosis
Mol Pharmacol 2001 59: 593-603. [Abstract] [Full Text] [PDF]  

Chainllie Young, Ya-Chun Huang, Chih-Hung Lin, Yu-Zen Shen, and Po-Wu Gean

Selective Enhancement of L-Type Calcium Currents by Corticotropin in Acutely Isolated Rat Amygdala Neurons
Mol Pharmacol 2001 59: 604-611. [Abstract] [Full Text] [PDF]  

Seifollah Ahmadi, Carolin Kotalla, Hans Gühring, Hiroshi Takeshima, Andreas Pahl, and Hanns Ulrich Zeilhofer

Modulation of Synaptic Transmission by Nociceptin/Orphanin FQ and Nocistatin in the Spinal Cord Dorsal Horn of Mutant Mice Lacking the Nociceptin/Orphanin FQ Receptor
Mol Pharmacol 2001 59: 612-618. [Abstract] [Full Text] [PDF]  

William D. Mallender, Debra Yager, Luisa Onstead, Michael R. Nichols, Christopher Eckman, Kumar Sambamurti, Lisa M. Kopcho, Jovita Marcinkeviciene, Robert A. Copeland, and Terrone L. Rosenberry

Characterization of Recombinant, Soluble -Secretase from an Insect Cell Expression System
Mol Pharmacol 2001 59: 619-626. [Abstract] [Full Text] [PDF]  

Christoph Funk, Christiane Ponelle, Gerd Scheuermann, and Michael Pantze

Cholestatic Potential of Troglitazone as a Possible Factor Contributing to Troglitazone-Induced Hepatotoxicity: In Vivo and in Vitro Interaction at the Canalicular Bile Salt Export Pump (Bsep) in the Rat
Mol Pharmacol 2001 59: 627-635. [Abstract] [Full Text] [PDF]  

Olivier Barbier, Caroline Albert, Isabelle Martineau, Michel Vallée, Kim High, Fernand Labrie, Dean W. Hum, Claude Labrie, and Alain Bélanger

Glucuronidation of the Nonsteroidal Antiestrogen EM-652 (SCH 57068), by Human and Monkey Steroid Conjugating UDP-Glucuronosyltransferase Enzymes
Mol Pharmacol 2001 59: 636-645. [Abstract] [Full Text] [PDF]  

Sven Wassmann, Ulrich Laufs, Anselm T. Bäumer, Kirsten Müller, Christian Konkol, Heinrich Sauer, Michael Böhm, and Georg Nickenig

Inhibition of Geranylgeranylation Reduces Angiotensin II-Mediated Free Radical Production in Vascular Smooth Muscle Cells: Involvement of Angiotensin AT1 Receptor Expression and Rac1 GTPase
Mol Pharmacol 2001 59: 646-654. [Abstract] [Full Text] [PDF]  

Errata:

Correction for Volume 58, p. 1222
Mol Pharmacol 2001 59: 655. [Full Text] [PDF]  

Correction for Volume 58, p. 1310
Mol Pharmacol 2001 59: 656. [Full Text] [PDF]  

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