Minireview:

Victor M. Gonzalez, Miguel A. Fuertes, Carlos Alonso, and Jose M. Perez

Is Cisplatin-Induced Cell Death Always Produced by Apoptosis?
Mol Pharmacol 2001 59: 657-663. [Full Text] [PDF]  

Articles:

Cornelis J. Elferink, Nie-Lin Ge, and Aviva Levine

Maximal Aryl Hydrocarbon Receptor Activity Depends on an Interaction with the Retinoblastoma Protein
Mol Pharmacol 2001 59: 664-673. [Abstract] [Full Text] [PDF]  

Xilong Zhao, Alexander Kuryatov, Jon M. Lindstrom, Jay Z. Yeh, and Toshio Narahashi

Nootropic Drug Modulation of Neuronal Nicotinic Acetylcholine Receptors in Rat Cortical Neurons
Mol Pharmacol 2001 59: 674-683. [Abstract] [Full Text] [PDF]  

Akihiko Sunami, Ian W. Glaaser, and Harry A. Fozzard

Structural and Gating Changes of the Sodium Channel Induced by Mutation of a Residue in the Upper Third of IVS6, Creating an External Access Path for Local Anesthetics
Mol Pharmacol 2001 59: 684-691. [Abstract] [Full Text] [PDF]  

M. Li, C. M. Bullock, D. J. Knauer, F. J. Ehlert, and Q. Y. Zhou

Identification of Two Prokineticin cDNAs: Recombinant Proteins Potently Contract Gastrointestinal Smooth Muscle
Mol Pharmacol 2001 59: 692-698. [Abstract] [Full Text] [PDF]  

Berend Tolner, John A. Hartley, and Daniel Hochhauser

Transcriptional Regulation of Topoisomerase II at Confluence and Pharmacological Modulation of Expression by bis-Benzimidazole Drugs
Mol Pharmacol 2001 59: 699-706. [Abstract] [Full Text] [PDF]  

Mary Ann Cox, Chung-Her Jenh, Waldemar Gonsiorek, Jay Fine, Satwant K. Narula, Paul J. Zavodny, and R. William Hipkin

Human Interferon-Inducible 10-kDa Protein and Human Interferon-Inducible T Cell Chemoattractant Are Allotopic Ligands for Human CXCR3: Differential Binding to Receptor States
Mol Pharmacol 2001 59: 707-715. [Abstract] [Full Text] [PDF]  

Sandra Wolff, Patricia A. Harper, Judy M. Y. Wong, Volker Mostert, Yanping Wang, and Josef Abel

Cell-Specific Regulation of Human Aryl Hydrocarbon Receptor Expression by Transforming Growth Factor-₁
Mol Pharmacol 2001 59: 716-724. [Abstract] [Full Text] [PDF]  

Atsushi Azuma, Peng Huang, Akira Matsuda, and William Plunkett

2'-C-Cyano-2'-deoxy-1--D-arabino-pentofuranosylcytosine: A Novel Anticancer Nucleoside Analog that Causes Both DNA Strand Breaks and G₂ Arrest
Mol Pharmacol 2001 59: 725-731. [Abstract] [Full Text] [PDF]  

Takashi Mori, Xilong Zhao, Yi Zuo, Gary L. Aistrup, Kiyonobu Nishikawa, William Marszalec, Jay Z. Yeh, and Toshio Narahashi

Modulation of Neuronal Nicotinic Acetylcholine Receptors by Halothane in Rat Cortical Neurons
Mol Pharmacol 2001 59: 732-743. [Abstract] [Full Text] [PDF]  

Ivan Rusyn, Maria B. Kadiiska, Anna Dikalova, Hiroshi Kono, Ming Yin, Koichiro Tsuchiya, Ronald P. Mason, Jeffrey M. Peters, Frank J. Gonzalez, Brahm H. Segal, Steven M. Holland, and Ronald G. Thurman

Phthalates Rapidly Increase Production of Reactive Oxygen Species in Vivo: Role of Kupffer Cells
Mol Pharmacol 2001 59: 744-750. [Abstract] [Full Text] [PDF]  

Adam R. Karpf, Brent C. Moore, Ted O. Ririe, and David A. Jones

Activation of the p53 DNA Damage Response Pathway after Inhibition of DNA Methyltransferase by 5-Aza-2'-deoxycytidine
Mol Pharmacol 2001 59: 751-757. [Abstract] [Full Text] [PDF]  

Bo Cen, Ying Xiong, Lan Ma, and Gang Pei

Direct and Differential Interaction of -Arrestins with the Intracellular Domains of Different Opioid Receptors
Mol Pharmacol 2001 59: 758-764. [Abstract] [Full Text] [PDF]  

Harleen Singh Ahuja, Sha Liu, Diane L. Crombie, Marcus Boehm, Mark D. Leibowitz, Richard A. Heyman, Christophe Depre, Laszlo Nagy, Peter Tontonoz, and Peter J. A. Davies

Differential Effects of Rexinoids and Thiazolidinediones on Metabolic Gene Expression in Diabetic Rodents
Mol Pharmacol 2001 59: 765-773. [Abstract] [Full Text] [PDF]  

Nancy A. Martin and Paul L. Prather

Interaction of Co-Expressed µ- and -Opioid Receptors in Transfected Rat Pituitary GH₃ Cells
Mol Pharmacol 2001 59: 774-783. [Abstract] [Full Text] [PDF]  

Ming-Jaw Don, Yen-Hwa Chang, Kuang-Kuo Chen, Li-Kang Ho, and Yat-Pang Chau

Induction of CDK Inhibitors (p21^WAF1 and p27^Kip1) and Bak in the -Lapachone-Induced Apoptosis of Human Prostate Cancer Cells
Mol Pharmacol 2001 59: 784-794. [Abstract] [Full Text] [PDF]  

Defeng Wu and Arthur I. Cederbaum

Sodium Salicylate Increases CYP2E1 Levels and Enhances Arachidonic Acid Toxicity in HepG2 Cells and Cultured Rat Hepatocytes
Mol Pharmacol 2001 59: 795-805. [Abstract] [Full Text] [PDF]  

Maarten T. Huisman, Johan W. Smit, Hugh R. Wiltshire, Richard M. W. Hoetelmans, Jos. H. Beijnen, and Alfred H. Schinkel

P-Glycoprotein Limits Oral Availability, Brain, and Fetal Penetration of Saquinavir Even with High Doses of Ritonavir
Mol Pharmacol 2001 59: 806-813. [Abstract] [Full Text] [PDF]  

Donglin Bai, Guoyun Zhu, Peter Pennefather, Michael F. Jackson, John F. MacDonald, and Beverley A. Orser

Distinct Functional and Pharmacological Properties of Tonic and Quantal Inhibitory Postsynaptic Currents Mediated by -Aminobutyric Acid_A Receptors in Hippocampal Neurons
Mol Pharmacol 2001 59: 814-824. [Abstract] [Full Text] [PDF]  

Ricardo Caballero, Eva Delpón, Carmen Valenzuela, Mónica Longobardo, Teresa González, and Juan Tamargo

Direct Effects of Candesartan and Eprosartan on Human Cloned Potassium Channels Involved in Cardiac Repolarization
Mol Pharmacol 2001 59: 825-836. [Abstract] [Full Text] [PDF]  

Kai Zhang, May Chew, Er Bin Yang, Kim Ping Wong, and Peter Mack

Modulation of Cisplatin Cytotoxicity and Cisplatin-Induced DNA Cross-Links in HepG2 Cells by Regulation of Glutathione-Related Mechanisms
Mol Pharmacol 2001 59: 837-843. [Abstract] [Full Text] [PDF]  

Nicole Lobitz, Günter Gisselmann, Hanns Hatt, and Christian H. Wetzel

A Single Amino-Acid in the TM1 Domain Is an Important Determinant of the Desensitization Kinetics of Recombinant Human and Guinea Pig -Homomeric 5-Hydroxytryptamine Type 3 Receptors
Mol Pharmacol 2001 59: 844-851. [Abstract] [Full Text] [PDF]  

Wai K. Wong, Kevin Chen, and Jean C. Shih

Regulation of Human Monoamine Oxidase B Gene by Sp1 and Sp3
Mol Pharmacol 2001 59: 852-859. [Abstract] [Full Text] [PDF]  

Hui Qin Wang, Michael P. Kim, Howard F. Tiano, Robert Langenbach, and Robert C. Smart

Protein Kinase C- Coordinately Regulates Cytosolic Phospholipase A₂ Activity and the Expression of Cyclooxygenase-2 through Different Mechanisms in Mouse Keratinocytes
Mol Pharmacol 2001 59: 860-866. [Abstract] [Full Text] [PDF]  

David Hreniuk, Michele Garay, William Gaarde, Brett P. Monia, Robert A. McKay, and Catherine L. Cioffi

Inhibition of C-Jun N-Terminal Kinase 1, but Not c-Jun N-Terminal Kinase 2, Suppresses Apoptosis Induced by Ischemia/Reoxygenation in Rat Cardiac Myocytes
Mol Pharmacol 2001 59: 867-874. [Abstract] [Full Text] [PDF]  

Magali Waelbroeck

Activation of Guanosine 5'-[-³⁵S]thio-triphosphate Binding through M₁ Muscarinic Receptors in Transfected Chinese Hamster Ovary Cell Membranes: 1. Mathematical Analysis of Catalytic G Protein Activation
Mol Pharmacol 2001 59: 875-885. [Abstract] [Full Text] [PDF] [APPENDIX]  

Magali Waelbroeck

Activation of Guanosine 5'-[-³⁵S]thio-triphosphate Binding through M₁ Muscarinic Receptors in Transfected Chinese Hamster Ovary Cell Membranes: 2. Testing the "Two-States" Model of Receptor Activation
Mol Pharmacol 2001 59: 886-893. [Abstract] [Full Text] [PDF] [APPENDIX]  

Takato Nikaido, Masashi Akiyama, Takahiro Moriya, and Shigenobu Shibata

Sensitized Increase of Period Gene Expression in the Mouse Caudate/Putamen Caused by Repeated Injection of Methamphetamine
Mol Pharmacol 2001 59: 894-900. [Abstract] [Full Text] [PDF]  

Seung Joon Baek, Kyung-Su Kim, Jennifer B. Nixon, Leigh C. Wilson, and Thomas E. Eling

Cyclooxygenase Inhibitors Regulate the Expression of a TGF- Superfamily Member That Has Proapoptotic and Antitumorigenic Activities
Mol Pharmacol 2001 59: 901-908. [Abstract] [Full Text] [PDF]  

Lovisa Afzelius, Ismael Zamora, Marianne Ridderström, Tommy B. Andersson, Anders Karlén, and Collen M. Masimirembwa

Competitive CYP2C9 Inhibitors: Enzyme Inhibition Studies, Protein Homology Modeling, and Three-Dimensional Quantitative Structure-Activity Relationship Analysis
Mol Pharmacol 2001 59: 909-919. [Abstract] [Full Text] [PDF]  

Éva Szárics, Lajos Nyikos, Péter Barabás, Ilona Kovács, Nina Skuban, Eszter Temesváriné-Major, Orsolya Egyed, Peter I. Nagy, József Kökösi, Krisztina Takács-Novák, and Julianna Kardos

Quinazolone-Alkyl-Carboxylic Acid Derivatives Inhibit Transmembrane Ca²⁺ Ion Flux to (+)-(S)--Amino-3-hydroxy-5-methylisoxazole-4-propionic Acid
Mol Pharmacol 2001 59: 920-928. [Abstract] [Full Text] [PDF]  

Matthew H. Wilson, Hilary A. Highfield, and Lee E. Limbird

The Role of a Conserved Inter-Transmembrane Domain Interface in Regulating _2a-Adrenergic Receptor Conformational Stability and Cell-Surface Turnover
Mol Pharmacol 2001 59: 929-938. [Abstract] [Full Text] [PDF]  

Ka Bian, Yael Harari, Meng Zhong, Mildred Lai, Gilbert Castro, Norman Weisbrodt, and Ferid Murad

Down-Regulation of Inducible Nitric-Oxide Synthase (NOS-2) During Parasite-Induced Gut Inflammation: A Path to Identify a Selective NOS-2 Inhibitor
Mol Pharmacol 2001 59: 939-947. [Abstract] [Full Text] [PDF]  

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