Perspectives:

Jean-Philippe Pin, Marie-Laure Parmentier, and Laurent Prézeau

Positive Allosteric Modulators for -Aminobutyric Acid_B Receptors Open New Routes for the Development of Drugs Targeting Family 3 G-Protein-Coupled Receptors
Mol Pharmacol 2001 60: 881-884. [Full Text] [PDF]  

Articles:

Victoria Smith, Florence Raynaud, Paul Workman, and Lloyd R. Kelland

Characterization of a Human Colorectal Carcinoma Cell Line with Acquired Resistance to Flavopiridol
Mol Pharmacol 2001 60: 885-893. [Abstract] [Full Text] [PDF]  

Olga Pol, Francesc Alameda, and Margarita M. Puig

Inflammation Enhances µ-Opioid Receptor Transcription and Expression in Mice Intestine
Mol Pharmacol 2001 60: 894-899. [Abstract] [Full Text] [PDF]  

Mathias Schmidt, Yang Lu, John M. Parant, Guillermina Lozano, Gerald Bacher, Thomas Beckers, and Zhen Fan

Differential Roles of p21^Waf1 and p27^Kip1 in Modulating Chemosensitivity and Their Possible Application in Drug Discovery Studies
Mol Pharmacol 2001 60: 900-906. [Abstract] [Full Text] [PDF]  

Michael L. Adams, Robert H. Pierce, Mary E. Vail, Collin C. White, Robert P. Tonge, Terrence J. Kavanagh, Nelson Fausto, Sidney D. Nelson, and Sam A. Bruschi

Enhanced Acetaminophen Hepatotoxicity in Transgenic Mice Overexpressing BCL-2
Mol Pharmacol 2001 60: 907-915. [Abstract] [Full Text] [PDF]  

Steven H. S. Lin, Amy C. Arai, Zhiwei Wang, Hans-Peter Nothacker, and Olivier Civelli

The Carboxyl Terminus of the Prolactin-Releasing Peptide Receptor Interacts with PDZ Domain Proteins Involved in -Amino-3-hydroxy-5-methylisoxazole-4-propionic Acid Receptor Clustering
Mol Pharmacol 2001 60: 916-923. [Abstract] [Full Text] [PDF]  

Luisa Iacovelli, Loredana Capobianco, Lorena Salvatore, Michele Sallese, Gabriel Maximo D'Ancona, and Antonio De Blasi

Thyrotropin Activates Mitogen-Activated Protein Kinase Pathway in FRTL-5 by a cAMP-Dependent Protein Kinase A-Independent Mechanism
Mol Pharmacol 2001 60: 924-933. [Abstract] [Full Text] [PDF]  

Yunhai Cui, Jörg König, and Dietrich Keppler

Vectorial Transport by Double-Transfected Cells Expressing the Human Uptake Transporter SLC21A8 and the Apical Export Pump ABCC2
Mol Pharmacol 2001 60: 934-943. [Abstract] [Full Text] [PDF]  

Pari Malherbe, Frédéric Knoflach, Clemens Broger, Serge Ohresser, Claudia Kratzeisen, Geo Adam, Heinz Stadler, John A. Kemp, and Vincent Mutel

Identification of Essential Residues Involved in the Glutamate Binding Pocket of the Group II Metabotropic Glutamate Receptor
Mol Pharmacol 2001 60: 944-954. [Abstract] [Full Text] [PDF]  

Andrzej Chruscinski, Marc E. Brede, Lorenz Meinel, Martin J. Lohse, Brian K. Kobilka, and Lutz Hein

Differential Distribution of -Adrenergic Receptor Subtypes in Blood Vessels of Knockout Mice Lacking ₁- or ₂-Adrenergic Receptors
Mol Pharmacol 2001 60: 955-962. [Abstract] [Full Text] [PDF]  

Stephan Urwyler, Johannes Mosbacher, Kurt Lingenhoehl, Jakob Heid, Karin Hofstetter, Wolfgang Froestl, Bernhard Bettler, and Klemens Kaupmann

Positive Allosteric Modulation of Native and Recombinant -Aminobutyric Acid_B Receptors by 2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its Aldehyde Analog CGP13501
Mol Pharmacol 2001 60: 963-971. [Abstract] [Full Text] [PDF]  

Ho Kim, Tae-Hoon Lee, Young Sun Hwang, Mi Ae Bang, Kang Hwa Kim, Jae Mi Suh, Hyo Kyun Chung, Dae-Yeul Yu, Kyung-Kwang Lee, O-Yu Kwon, Heung Kyu Ro, and Minho Shong

Methimazole As an Antioxidant and Immunomodulator in Thyroid Cells: Mechanisms Involving Interferon- Signaling and H₂O₂ Scavenging
Mol Pharmacol 2001 60: 972-980. [Abstract] [Full Text] [PDF]  

Sharon M. Gowan, Robert Heald, Malcolm F. G. Stevens, and Lloyd R. Kelland

Potent Inhibition of Telomerase by Small-Molecule Pentacyclic Acridines Capable of Interacting with G-Quadruplexes
Mol Pharmacol 2001 60: 981-988. [Abstract] [Full Text] [PDF]  

Hideaki Kanki, Mariko Kinoshita, Akinori Akaike, Masamichi Satoh, Yasuo Mori, and Shuji Kaneko

Activation of Inositol 1,4,5-Trisphosphate Receptor Is Essential for the Opening of Mouse TRP5 Channels
Mol Pharmacol 2001 60: 989-998. [Abstract] [Full Text] [PDF]  

Mounia Azzi, Graciela Piñeyro, Stéphanie Pontier, Stéphane Parent, Hervé Ansanay, and Michel Bouvier

Allosteric Effects of G Protein Overexpression on the Binding of -Adrenergic Ligands with Distinct Inverse Efficacies
Mol Pharmacol 2001 60: 999-1007. [Abstract] [Full Text] [PDF]  

C. Marc Luetjens, Donat Kögel, Claus Reimertz, Heiko Düßmann, Andrea Renz, Klaus Schulze-Osthoff, Anna-Liisa Nieminen, Monika Poppe, and Jochen H. M. Prehn

Multiple Kinetics of Mitochondrial Cytochrome c Release in Drug-Induced Apoptosis
Mol Pharmacol 2001 60: 1008-1019. [Abstract] [Full Text] [PDF]  

John A. Gray, Douglas J. Sheffler, Anushree Bhatnagar, Jason A. Woods, Sandra J. Hufeisen, Jeffrey L. Benovic, and Bryan L. Roth

Cell-Type Specific Effects of Endocytosis Inhibitors on 5-Hydroxytryptamine_2A Receptor Desensitization and Resensitization Reveal an Arrestin-, GRK2-, and GRK5-Independent Mode of Regulation in Human Embryonic Kidney 293 Cells
Mol Pharmacol 2001 60: 1020-1030. [Abstract] [Full Text] [PDF]  

Ricardo Hermosilla and Ralf Schülein

Sorting Functions of the Individual Cytoplasmic Domains of the G Protein-Coupled Vasopressin V₂ Receptor in Madin Darby Canine Kidney Epithelial Cells
Mol Pharmacol 2001 60: 1031-1039. [Abstract] [Full Text] [PDF]  

Yuji Ishii, Aya Miyoshi, Ryoichi Watanabe, Kazuoki Tsuruda, Minoru Tsuda, Yuki Yamaguchi-Nagamatsu, Kunihiro Yoshisue, Mitsuko Tanaka, Daisuke Maji, Satoru Ohgiya, and Kazuta Oguri

Simultaneous Expression of Guinea Pig UDP-Glucuronosyltransferase 2B21 and 2B22 in COS-7 Cells enhances UDP-Glucuronosyltransferase 2B21-Catalyzed Morphine-6-Glucuronide Formation
Mol Pharmacol 2001 60: 1040-1048. [Abstract] [Full Text] [PDF]  

Carina Shayo, Natalia Fernandez, Bibiana Lemos Legnazzi, Federico Monczor, Alejandro Mladovan, Alberto Baldi, and Carlos Davio

Histamine H2 Receptor Desensitization: Involvement of a Select Array of G Protein-Coupled Receptor Kinases
Mol Pharmacol 2001 60: 1049-1056. [Abstract] [Full Text] [PDF]  

Zhan-Guo Gao, Jacqueline E. Van Muijlwijk-Koezen, Aishe Chen, Christa E. Müller, Adriaan P. Ijzerman, and Kenneth A. Jacobson

Allosteric Modulation of A₃ Adenosine Receptors by a Series of 3-(2-Pyridinyl)isoquinoline Derivatives
Mol Pharmacol 2001 60: 1057-1063. [Abstract] [Full Text] [PDF]  

Jin Li, Chongguang Chen, Peng Huang, and Lee-Yuan Liu-Chen

Inverse Agonist Up-Regulates the Constitutively Active D3.49(164)Q Mutant of the Rat µ-Opioid Receptor by Stabilizing the Structure and Blocking Constitutive Internalization and Down-Regulation
Mol Pharmacol 2001 60: 1064-1075. [Abstract] [Full Text] [PDF]  

Marc Rubenzik, Eva Varga, Dagmar Stropova, William R. Roeske, and Henry I. Yamamura

Expression of -Transducin in Chinese Hamster Ovary Cells Stably Transfected with the Human -Opioid Receptor Attenuates Chronic Opioid Agonist-Induced Adenylyl Cyclase Superactivation
Mol Pharmacol 2001 60: 1076-1082. [Abstract] [Full Text] [PDF]  

Yuh-Chiang Shen, Cheng-Jen Chou, Wen-Fei Chiou, and Chieh-Fu Chen

Anti-Inflammatory Effects of the Partially Purified Extract of Radix Stephaniae tetrandrae: Comparative Studies of Its Active Principles Tetrandrine and Fangchinoline on Human Polymorphonuclear Leukocyte Functions
Mol Pharmacol 2001 60: 1083-1090. [Abstract] [Full Text] [PDF]  

James M. Pombrio, Adam Giangreco, Liqiong Li, Michael F. Wempe, M. W. Anders, Douglas H. Sweet, John B. Pritchard, and Nazzareno Ballatori

Mercapturic Acids (N-Acetylcysteine S-Conjugates) as Endogenous Substrates for the Renal Organic Anion Transporter-1
Mol Pharmacol 2001 60: 1091-1099. [Abstract] [Full Text] [PDF]  

George Baillie, Simon J. MacKenzie, and Miles D. Houslay

Phorbol 12-myristate 13-acetate Triggers the Protein Kinase A-Mediated Phosphorylation and Activation of the PDE4D5 cAMP Phosphodiesterase in Human Aortic Smooth Muscle Cells through a Route Involving Extracellular Signal Regulated Kinase (ERK)
Mol Pharmacol 2001 60: 1100-1111. [Abstract] [Full Text] [PDF]  

Béatrice Hechler, Paul Toselli, Catherine Ravanat, Christian Gachet, and Katya Ravid

Mpl Ligand Increases P2Y1 Receptor Gene Expression in Megakaryocytes with No Concomitant Change in Platelet Response to ADP
Mol Pharmacol 2001 60: 1112-1120. [Abstract] [Full Text] [PDF]  

Juan Carlos Gomora, Asif N. Daud, Marco Weiergräber, and Edward Perez-Reyes

Block of Cloned Human T-Type Calcium Channels by Succinimide Antiepileptic Drugs
Mol Pharmacol 2001 60: 1121-1132. [Abstract] [Full Text] [PDF]  

Remko A. Bakker, Stefan B. J. Schoonus, Martine J. Smit, Henk Timmerman, and Rob Leurs

Histamine H₁-Receptor Activation of Nuclear Factor-B: Roles for G- and G_q/11-Subunits in Constitutive and Agonist-Mediated Signaling
Mol Pharmacol 2001 60: 1133-1142. [Abstract] [Full Text] [PDF]  

Thack T. Lang, Milada Selner, James D. Young, and Carol E. Cass

Acquisition of Human Concentrative Nucleoside Transporter 2 (hCNT2) Activity by Gene Transfer Confers Sensitivity to Fluoropyrimidine Nucleosides in Drug-Resistant Leukemia Cells
Mol Pharmacol 2001 60: 1143-1152. [Abstract] [Full Text] [PDF]  

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