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Other Issues:
December 2001; 60 (6)   [Index by Author]  [Cover Caption]
       Minireview
       Perspectives
       Accelerated Communications
       Articles
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To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

Minireview:

H. Niedner, R. Christen, X. Lin, A. Kondo, and S. B. Howell
Identification of Genes That Mediate Sensitivity to Cisplatin
Mol Pharmacol 2001 60: 1153-1160. [Abstract] [Full Text] [PDF]  

Perspectives:

Gabor Tigyi
Selective Ligands for Lysophosphatidic Acid Receptor Subtypes: Gaining Control over the Endothelial Differentiation Gene Family
Mol Pharmacol 2001 60: 1161-1164. [Full Text] [PDF]  

Kyung-Ah Kim and Mark von Zastrow
Old Drugs Learn New Tricks: Insights from Mammalian Trace Amine Receptors
Mol Pharmacol 2001 60: 1165-1167. [Full Text] [PDF]  

Accelerated Communications:

Val J. Watts, Ronald Taussig, Rachael L. Neve, and Kim A. Neve
Dopamine D2 Receptor-Induced Heterologous Sensitization of Adenylyl Cyclase Requires Galpha s: Characterization of Galpha s-Insensitive Mutants of Adenylyl Cyclase V
Mol Pharmacol 2001 60: 1168-1172. [Abstract] [Full Text] [PDF]  

Christopher E. Heise, Webster L. Santos, Ann M. Schreihofer, Brian H. Heasley, Yurii V. Mukhin, Timothy L. Macdonald, and Kevin R. Lynch
Activity of 2-Substituted Lysophosphatidic Acid (LPA) Analogs at LPA Receptors: Discovery of a LPA1/LPA3 Receptor Antagonist
Mol Pharmacol 2001 60: 1173-1180. [Abstract] [Full Text] [PDF]  

James R. Bunzow, Mark S. Sonders, Seksiri Arttamangkul, Laura M. Harrison, Ge Zhang, Denise I. Quigley, Tristan Darland, Katherine L. Suchland, Shailaja Pasumamula, James L. Kennedy, Susan B. Olson, R. Ellen Magenis, Susan G. Amara, and David K. Grandy
Amphetamine, 3,4-Methylenedioxymethamphetamine, Lysergic Acid Diethylamide, and Metabolites of the Catecholamine Neurotransmitters Are Agonists of a Rat Trace Amine Receptor
Mol Pharmacol 2001 60: 1181-1188. [Abstract] [Full Text] [PDF]  

Russell S. Thomas, David R. Rank, Sharron G. Penn, Gina M. Zastrow, Kevin R. Hayes, Kalyan Pande, Edward Glover, Tomi Silander, Mark W. Craven, Janardan K. Reddy, Stevan B. Jovanovich, and Christopher A. Bradfield
Identification of toxicologically predictive gene sets using cDNA microarrays
Mol Pharmacol 2001 60: 1189-1194. [Abstract] [Full Text] [PDF]  

Selvi C. Jeyaraj, Maqsood A. Chotani, Srabani Mitra, Herbert E. Gregg, Nicholas A. Flavahan, and Keith J. Morrison
Cooling Evokes Redistribution of alpha 2C-Adrenoceptors from Golgi to Plasma Membrane in Transfected Human Embryonic Kidney 293 Cells
Mol Pharmacol 2001 60: 1195-1200. [Abstract] [Full Text] [PDF]  

Articles:

Y. Wang, E. F. R. Pereira, A. D. J. Maus, N. S. Ostlie, D. Navaneetham, S. Lei, E. X. Albuquerque, and B. M. Conti-Fine
Human Bronchial Epithelial and Endothelial Cells Express alpha 7 Nicotinic Acetylcholine Receptors
Mol Pharmacol 2001 60: 1201-1209. [Abstract] [Full Text] [PDF]  

Melissa T. Kelley, Tilmann Bürckstümmer, Katharina Wenzel-Seifert, Stefan Dove, Armin Buschauer, and Roland Seifert
Distinct Interaction of Human and Guinea Pig Histamine H2-Receptor with Guanidine-Type Agonists
Mol Pharmacol 2001 60: 1210-1225. [Abstract] [Full Text] [PDF]  

Paul A. Nony and Rick G. Schnellmann
Interactions between Collagen IV and Collagen-Binding Integrins in Renal Cell Repair after Sublethal Injury
Mol Pharmacol 2001 60: 1226-1234. [Abstract] [Full Text] [PDF]  

Begoña Comín-Anduix, Neus Agell, Oriol Bachs, Judit Ovádi, and Marta Cascante
A New Bis-Indole, KARs, Induces Selective M Arrest with Specific Spindle Aberration in Neuroblastoma Cell Line SH-SY5Y
Mol Pharmacol 2001 60: 1235-1242. [Abstract] [Full Text] [PDF]  

Lianne B. Dale, Moshmi Bhattacharya, Jennifer L. Seachrist, Pieter H. Anborgh, and Stephen S. G. Ferguson
Agonist-Stimulated and Tonic Internalization of Metabotropic Glutamate Receptor 1a in Human Embryonic Kidney 293 Cells: Agonist-Stimulated Endocytosis Is beta -Arrestin1 Isoform-Specific
Mol Pharmacol 2001 60: 1243-1253. [Abstract] [Full Text] [PDF]  

Kappei Tsukahara, Tatsuo Watanabe, Naoko Hata-Sugi, Kentaro Yoshimatsu, Hiroto Okayama, and Takeshi Nagasu
Anticancer Agent E7070 Inhibits Amino Acid and Uracil Transport in Fission Yeast
Mol Pharmacol 2001 60: 1254-1259. [Abstract] [Full Text] [PDF]  

Javier Corchero, Camille P. Granvil, Taro E. Akiyama, Graham P. Hayhurst, Satish Pimprale, Lionel Feigenbaum, Jeffrey R. Idle, and Frank J. Gonzalez
The CYP2D6 Humanized Mouse: Effect of the Human CYP2D6 Transgene and HNF4alpha on the Disposition of Debrisoquine in the Mouse
Mol Pharmacol 2001 60: 1260-1267. [Abstract] [Full Text] [PDF]  

Pamela S. Schwartz and David J. Waxman
Cyclophosphamide Induces Caspase 9-Dependent Apoptosis in 9L Tumor Cells
Mol Pharmacol 2001 60: 1268-1279. [Abstract] [Full Text] [PDF]  

Bernhard J. Fromme, Arieh A. Katz, Roger W. Roeske, Robert P. Millar, and Colleen A. Flanagan
Role of Aspartate7.32(302) of the Human Gonadotropin-Releasing Hormone Receptor in Stabilizing a High-Affinity Ligand Conformation
Mol Pharmacol 2001 60: 1280-1287. [Abstract] [Full Text] [PDF]  

Mona S. Jhaveri, Conrad Wagner, and Jane B. Trepel
Impact of Extracellular Folate Levels on Global Gene Expression
Mol Pharmacol 2001 60: 1288-1295. [Abstract] [Full Text] [PDF]  

Luba Benimetskaya, Paul Miller, Simon Benimetsky, Anna Maciaszek, Piotr Guga, Serge L. Beaucage, Andrzej Wilk, Andrzej Grajkowski, Anthony L. Halperin, and C. A. Stein
Inhibition of Potentially Anti-Apoptotic Proteins by Antisense Protein Kinase C-alpha (Isis 3521) and Antisense bcl-2 (G3139) Phosphorothioate Oligodeoxynucleotides: Relationship to the Decreased Viability of T24 Bladder and PC3 Prostate Cancer Cells
Mol Pharmacol 2001 60: 1296-1307. [Abstract] [Full Text] [PDF]  

Philbert Kirigiti, Ying Bai, Yong-Feng Yang, Xiaorong Li, Biao Li, Gary Brewer, and Curtis A. Machida
Agonist-Mediated Down-Regulation of Rat beta 1-Adrenergic Receptor Transcripts: Role of Potential Post-Transcriptional Degradation Factors
Mol Pharmacol 2001 60: 1308-1324. [Abstract] [Full Text] [PDF]  

Shane C. Masters, Hongzhu Yang, Sandeep Robert Datta, Michael E. Greenberg, and Haian Fu
14-3-3 Inhibits Bad-Induced Cell Death through Interaction with Serine-136
Mol Pharmacol 2001 60: 1325-1331. [Abstract] [Full Text] [PDF]  

Hans-Dieter Orzechowski, Astrid Günther, Stefan Menzel, Andreas Zimmermann, Heiko Funke-Kaiser, Robert Real, Thomas Subkowski, Frank S. Zollmann, and Martin Paul
Transcriptional Mechanism of Protein Kinase C-Induced Isoform-Specific Expression of the Gene for Endothelin-Converting Enzyme-1in Human Endothelial Cells
Mol Pharmacol 2001 60: 1332-1342. [Abstract] [Full Text] [PDF]  

Eckhard Ficker, Wolfgang Jarolimek, and Arthur M. Brown
Molecular Determinants of Inactivation and Dofetilide Block in ether a-go-go (EAG) Channels and EAG-Related K+ Channels
Mol Pharmacol 2001 60: 1343-1348. [Abstract] [Full Text] [PDF]  

Glen L. Alberts, Christopher L. Chio, and Wha Bin Im
Allosteric Modulation of the Human 5-HT7A Receptor by Lipidic Amphipathic Compounds
Mol Pharmacol 2001 60: 1349-1355. [Abstract] [Full Text] [PDF]  

Keshore R. Bidasee, Ü. Deniz Dinçer, and Henry R. Besch, Jr.
Ryanodine Receptor Dysfunction in Hearts of Streptozotocin-Induced Diabetic Rats
Mol Pharmacol 2001 60: 1356-1364. [Abstract] [Full Text] [PDF]  

Roger L. Papke, Benjamin A. Horenstein, and Andon N. Placzek
Inhibition of Wild-Type and Mutant Neuronal Nicotinic Acetylcholine Receptors by Local Anesthetics
Mol Pharmacol 2001 60: 1365-1374. [Abstract] [Full Text] [PDF]  

Ai-Dong Qi, Alexander C. Zambon, Paul A. Insel, and Robert A. Nicholas
An Arginine/Glutamine Difference at the Juxtaposition of Transmembrane Domain 6 and the Third Extracellular Loop Contributes to the Markedly Different Nucleotide Selectivities of Human and Canine P2Y11 Receptors
Mol Pharmacol 2001 60: 1375-1382. [Abstract] [Full Text] [PDF]  

Stéphane Léonce, Valérie Pérez, Stéphanie Lambel, Delphine Peyroulan, François Tillequin, Sylvie Michel, Michel Koch, Bruno Pfeiffer, Ghanem Atassi, John A Hickman, and Alain Pierré
Induction of Cyclin E and Inhibition of DNA Synthesis by the Novel Acronycine Derivative S23906-1 Precede the Irreversible Arrest of Tumor Cells in S Phase Leading to Apoptosis
Mol Pharmacol 2001 60: 1383-1391. [Abstract] [Full Text] [PDF]  

Françoise Richard, Séverine Barroso, Jean Martinez, Catherine Labbé-Jullié, and Patrick Kitabgi
Agonism, Inverse Agonism, and Neutral Antagonism at the Constitutively Active Human Neurotensin Receptor 2
Mol Pharmacol 2001 60: 1392-1398. [Abstract] [Full Text] [PDF]  

Kenneth E. Thummel, Cynthia Brimer, Kazuto Yasuda, Jaideep Thottassery, Tauri Senn, Yvonne Lin, Hitoshi Ishizuka, Evan Kharasch, John Schuetz, and Erin Schuetz
Transcriptional Control of Intestinal Cytochrome P-4503A by 1alpha ,25-Dihydroxy Vitamin D3
Mol Pharmacol 2001 60: 1399-1406. [Abstract] [Full Text] [PDF]  

P. J. Loll, C. T. Sharkey, S. J. O'Connor, C. M. Dooley, E. O'Brien, M. Devocelle, K. B. Nolan, B. S. Selinsky, and D. J. Fitzgerald
O-Acetylsalicylhydroxamic Acid, a Novel Acetylating Inhibitor of Prostaglandin H2 Synthase: Structural and Functional Characterization of Enzyme-Inhibitor Interactions
Mol Pharmacol 2001 60: 1407-1413. [Abstract] [Full Text] [PDF]  

B. N. Atkinson, S. C. Bell, M. De Vivo, L. R. Kowalski, S. M. Lechner, V. I. Ognyanov, C.-S. Tham, C. Tsai, J. Jia, D. Ashton, and M. A. Klitenick
ALX 5407: A Potent, Selective Inhibitor of the hGlyT1 Glycine Transporter
Mol Pharmacol 2001 60: 1414-1420. [Abstract] [Full Text] [PDF]  

Zhaohui Luo and Ronald N. Hines
Regulation of Flavin-Containing Monooxygenase 1 Expression by Ying Yang 1 and Hepatic Nuclear Factors 1 and 4
Mol Pharmacol 2001 60: 1421-1430. [Abstract] [Full Text] [PDF]  

Kiyotsugu Yoshida and Donald Kufe
Negative Regulation of the SHPTP1 Protein Tyrosine Phosphatase by Protein Kinase C delta in Response to DNA Damage
Mol Pharmacol 2001 60: 1431-1438. [Abstract] [Full Text] [PDF]  

Ching-Chow Chen, Kuo-Tung Chiu, Shu-Ting Chan, and Ji-Wang Chern
Conjugated Polyhydroxybenzene Derivatives Block Tumor Necrosis Factor-alpha -Mediated Nuclear Factor-kappa B Activation and Cyclooxygenase-2 Gene Transcription by Targeting Ikappa B Kinase Activity
Mol Pharmacol 2001 60: 1439-1448. [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

About the cover: 4-Phenylimidazole docked into the active site of the CYP2B models. A, CYP2B4. B, CYP2B5. C, the interaction between the B'-C loop and helix I in CYP2B5. D, CYP2B1. The heme is shown in red. 4-Phenylimidazole is shown in yellow with the nitrogen in blue pointing to the heme iron. Mol Pharmacol 59:475-484.



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