Mol Pharm -- Table of Contents (61 [1])

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January 2002; 61 (1)   [Index by Author] [Cover Caption]

       Accelerated Communications

       Articles

       Errata

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Accelerated Communications:

Akiko Ueda, Hisham K. Hamadeh, Heather K. Webb, Yukio Yamamoto, Tatsuya Sueyoshi, Cynthia A. Afshari, Jürgen M. Lehmann, and Masahiko Negishi: Diverse Roles of the Nuclear Orphan Receptor CAR in Regulating Hepatic Genes in Response to Phenobarbital
Mol Pharmacol 2002 61: 1-6. [Abstract] [Full Text] [PDF]

Douglas J. A. Adamson, David Frew, Roger Tatoud, C. Roland Wolf, and Colin N. A. Palmer: Diclofenac Antagonizes Peroxisome Proliferator-Activated Receptor- $gamma$ Signaling
Mol Pharmacol 2002 61: 7-12. [Abstract] [Full Text] [PDF]

Articles:

Andrea I. Loaiza-Pérez, Valentina Trapani, Curtis Hose, Sheo S. Singh, Jane B. Trepel, Malcolm F. G. Stevens, Tracey D. Bradshaw, and Edward A. Sausville: Aryl Hydrocarbon Receptor Mediates Sensitivity of MCF-7 Breast Cancer Cells to Antitumor Agent 2-(4-Amino-3-methylphenyl) Benzothiazole
Mol Pharmacol 2002 61: 13-19. [Abstract] [Full Text] [PDF]

Orly Dym, Ioannis Xenarios, Hengming Ke, and John Colicelli: Molecular Docking of Competitive Phosphodiesterase Inhibitors
Mol Pharmacol 2002 61: 20-25. [Abstract] [Full Text] [PDF]

Reiko Aida, Takahiro Moriya, Miwa Araki, Masashi Akiyama, Keiji Wada, Etsuko Wada, and Shigenobu Shibata: Gastrin-Releasing Peptide Mediates Photic Entrainable Signals to Dorsal Subsets of Suprachiasmatic Nucleus via Induction of Period Gene in Mice
Mol Pharmacol 2002 61: 26-34. [Abstract] [Full Text] [PDF]

Roland A. Cooper, Michael T. Ferdig, Xin-Zhuan Su, Lyann M. B. Ursos, Jianbing Mu, Takashi Nomura, Hisashi Fujioka, David A. Fidock, Paul D. Roepe, and Thomas E. Wellems: Alternative Mutations at Position 76 of the Vacuolar Transmembrane Protein PfCRT Are Associated with Chloroquine Resistance and Unique Stereospecific Quinine and Quinidine Responses in Plasmodium falciparum
Mol Pharmacol 2002 61: 35-42. [Abstract] [Full Text] [PDF]

Silvia Di Angelantonio, Valeria Costa, Paolo Carloni, Luigi Messori, and Andrea Nistri: A Novel Class of Peptides with Facilitating Action on Neuronal Nicotinic Receptors of Rat Chromaffin Cells in Vitro: Functional and Molecular Dynamics Studies
Mol Pharmacol 2002 61: 43-54. [Abstract] [Full Text] [PDF]

T. Bushell, T. Endoh, A. A. Simen, D. Ren, V. P. Bindokas, and R. J. Miller: Molecular Components of Tolerance to Opiates in Single Hippocampal Neurons
Mol Pharmacol 2002 61: 55-64. [Abstract] [Full Text] [PDF]

Gayathri Swaminath, Jacqueline Steenhuis, Brian Kobilka, and Tae Weon Lee: Allosteric Modulation of $beta$ ₂-Adrenergic Receptor by Zn²⁺
Mol Pharmacol 2002 61: 65-72. [Abstract] [Full Text] [PDF]

Jin Li, Jian-Guo Li, Chongguang Chen, Fengqin Zhang, and Lee-Yuan Liu-Chen: Molecular Basis of Differences in ( $-$ )(trans)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidiny)-cyclohexyl]benzeneacetamide-Induced Desensitization and Phosphorylation between Human and Rat $kappa$ -Opioid Receptors Expressed in Chinese Hamster Ovary Cells
Mol Pharmacol 2002 61: 73-84. [Abstract] [Full Text] [PDF]

Armelle Pindon, Geert van Hecke, Paul van Gompel, Anne S. Lesage, Josée E. Leysen, and Mirek Jurzak: Differences in Signal Transduction of Two 5-HT₄ Receptor Splice Variants: Compound Specificity and Dual Coupling with G $alpha$ s- and G $alpha$ i/o-Proteins
Mol Pharmacol 2002 61: 85-96. [Abstract] [Full Text] [PDF]

G. Garthwaite, D. A. Goodwin, S. Neale, D. Riddall, and J. Garthwaite: Soluble Guanylyl Cyclase Activator YC-1 Protects White Matter Axons from Nitric Oxide Toxicity and Metabolic Stress, Probably through Na⁺ Channel Inhibition
Mol Pharmacol 2002 61: 97-104. [Abstract] [Full Text] [PDF]

Yi Huang and Weimin Fan: I $kappa$ B Kinase Activation Is Involved in Regulation of Paclitaxel-Induced Apoptosis in Human Tumor Cell Lines
Mol Pharmacol 2002 61: 105-113. [Abstract] [Full Text] [PDF]

Tatsurou Yagami, Keiichi Ueda, Kenji Asakura, Satoshi Hata, Takayuki Kuroda, Toshiyuki Sakaeda, Nobuo Takasu, Kazushige Tanaka, Takefumi Gemba, and Yozo Hori: Human Group IIA Secretory Phospholipase A₂ Induces Neuronal Cell Death via Apoptosis
Mol Pharmacol 2002 61: 114-126. [Abstract] [Full Text] [PDF]

Logos Curtis, Bruno Buisson, Sonia Bertrand, and Daniel Bertrand: Potentiation of Human $alpha$ 4 $beta$ 2 Neuronal Nicotinic Acetylcholine Receptor by Estradiol
Mol Pharmacol 2002 61: 127-135. [Abstract] [Full Text] [PDF]

Ronald A. Li, Irene L. Ennis, Gordon F. Tomaselli, and Eduardo Marbán: Structural Basis of Differences in Isoform-Specific Gating and Lidocaine Block between Cardiac and Skeletal Muscle Sodium Channels
Mol Pharmacol 2002 61: 136-141. [Abstract] [Full Text] [PDF]

Ye Liang, Karen D. Nylander, Chaohua Yan, and Nina Felice Schor: Role of Caspase 3-Dependent Bcl-2 Cleavage in Potentiation of Apoptosis by Bcl-2
Mol Pharmacol 2002 61: 142-149. [Abstract] [Full Text] [PDF]

Frédéric Sgard, Eric Charpantier, Sonia Bertrand, Nancy Walker, Daniel Caput, David Graham, Daniel Bertrand, and François Besnard: A Novel Human Nicotinic Receptor Subunit, $alpha$ 10, That Confers Functionality to the $alpha$ 9-Subunit
Mol Pharmacol 2002 61: 150-159. [Abstract] [Full Text] [PDF]

Stefan Buller, Darius Paul Zlotos, Klaus Mohr, and John Ellis: Allosteric Site on Muscarinic Acetylcholine Receptors: A Single Amino Acid in Transmembrane Region 7 Is Critical to the Subtype Selectivities of Caracurine V Derivatives and Alkane-Bisammonium Ligands
Mol Pharmacol 2002 61: 160-168. [Abstract] [Full Text] [PDF]

Robert W. Peoples and Hong Ren: Inhibition of N-Methyl-D-aspartate Receptors by Straight-Chain Diols: Implications for the Mechanism of the Alcohol Cutoff Effect
Mol Pharmacol 2002 61: 169-176. [Abstract] [Full Text] [PDF]

Stuart D. Shumway, Craig M. Berchtold, Michael N. Gould, and Shigeki Miyamoto: Evidence for Unique Calmodulin-Dependent Nuclear Factor- $kappa$ B Regulation in WEHI-231 B Cells
Mol Pharmacol 2002 61: 177-185. [Abstract] [Full Text] [PDF]

Marie-Jeanne Papandréou, Rym Barbouche, Régis Guieu, Marie Paule Kieny, and Emmanuel Fenouillet: The $alpha$ -Glucosidase Inhibitor 1-Deoxynojirimycin Blocks Human Immunodeficiency Virus Envelope Glycoprotein-Mediated Membrane Fusion at the CXCR4 Binding Step
Mol Pharmacol 2002 61: 186-193. [Abstract] [Full Text] [PDF]

Hirokazu Hara and Tetsuo Adachi: Contribution of Hepatocyte Nuclear Factor-4 to Down-Regulation of CYP2D6 Gene Expression by Nitric Oxide
Mol Pharmacol 2002 61: 194-200. [Abstract] [Full Text] [PDF]

Diane E. Mason, Kathy E. Mitchell, Yan Li, Melissa R. Finley, and Lisa C. Freeman: Molecular Basis of Voltage-Dependent Potassium Currents in Porcine Granulosa Cells
Mol Pharmacol 2002 61: 201-213. [Abstract] [Full Text] [PDF]

Stephan Theis, Bianka Hartrodt, Gabor Kottra, Klaus Neubert, and Hannelore Daniel: Defining Minimal Structural Features in Substrates of the H⁺/Peptide Cotransporter PEPT2 Using Novel Amino Acid and Dipeptide Derivatives
Mol Pharmacol 2002 61: 214-221. [Abstract] [Full Text] [PDF]

Yan Zhou, Geetha Achanta, Helene Pelicano, Varsha Gandhi, William Plunkett, and Peng Huang: Action of (E)-2'-Deoxy-2'-(fluoromethylene)cytidine on DNA Metabolism: Incorporation, Excision, and Cellular Response
Mol Pharmacol 2002 61: 222-229. [Abstract] [Full Text] [PDF]

Jennifer M. Kulak, J. Michael McIntosh, and Maryka Quik: Loss of Nicotinic Receptors in Monkey Striatum after 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Treatment Is Due to a Decline in $alpha$ -Conotoxin MII Sites
Mol Pharmacol 2002 61: 230-238. [Abstract] [Full Text] [PDF]

Jordi Gomez-Ramirez, Jordi Ortiz, and Isaac Blanco: Presynaptic H₃ Autoreceptors Modulate Histamine Synthesis through cAMP Pathway
Mol Pharmacol 2002 61: 239-245. [Abstract] [Full Text] [PDF]

Errata:

: Correction to "Sorting functions of the individual cytoplasmic domains of the G protein-coupled vasopressin V₂ receptor in Madin Darby canine kidney epithelial cells"
Mol Pharmacol 2002 61: 246. [Full Text] [PDF]

: Correction to "Structural mimicry in G protein-coupled receptors: implications of the high-resolution structure of rhodopsin for structure-function analysis of rhodopsin-like receptors"
Mol Pharmacol 2002 61: 247. [Full Text] [PDF]

: Correction to "The CYP2D6 humanized mouse: effect of the human CYP2D6 transgene and HNF4 $alpha$ on the disposition of debrisoquine in the mouse"
Mol Pharmacol 2002 61: 248. [Full Text] [PDF]

Cover Caption:

About the cover: Three-dimensional molecular representation of the distribution of positively charge residues in rhodopsin.The C $alpha$ trace of rhodopsin (yellow) is viewed perpendicular tothe transmembrane domain axis, with the extracellular side onthe top and the intracellular side on the bottom. The side chainsof Arg and Lys are shownin blue sticks. To represent the membranebilayer, several phospholipid molecules (phosphatidylcholinesin the extracellular leaflet and negatively charged phosphatidylserinesin the cytoplasmic leaflet) are shown. Mol Pharmacol 60:1-19.