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March 2002; 61 (3)   [Index by Author]  [Cover Caption]
       Perspectives
       Articles
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Perspectives:

Rennolds S Ostrom
New Determinants of Receptor-Effector Coupling: Trafficking and Compartmentation in Membrane Microdomains
Mol Pharmacol 2002 61: 473-476. [Full Text] [PDF]  

Articles:

Maria Kouznetsova, Brooke Kelley, Maoxing Shen, and Stanley A. Thayer
Desensitization of Cannabinoid-Mediated Presynaptic Inhibition of Neurotransmission Between Rat Hippocampal Neurons in Culture
Mol Pharmacol 2002 61: 477-485. [Abstract] [Full Text] [PDF]  

Ting-Yu Chin, Hsiou-Min Hwang, and Sheau-Huei Chueh
Distinct Effects of Different Calcium-Mobilizing Agents on Cell Death in NG108-15 Neuroblastoma X Glioma Cells
Mol Pharmacol 2002 61: 486-494. [Abstract] [Full Text] [PDF]  

Kishore K. Khan, You Qun He, Tammy L. Domanski, and James R. Halpert
Midazolam Oxidation by Cytochrome P450 3A4 and Active-Site Mutants: an Evaluation of Multiple Binding Sites and of the Metabolic Pathway That Leads to Enzyme Inactivation
Mol Pharmacol 2002 61: 495-506. [Abstract] [Full Text] [PDF]  

Xanthi I. Couroucli, Stephen E. Welty, Robert S. Geske, and Bhagavatula Moorthy
Regulation of Pulmonary and Hepatic Cytochrome P4501A Expression in the Rat by Hyperoxia: Implications for Hyperoxic Lung Injury
Mol Pharmacol 2002 61: 507-515. [Abstract] [Full Text] [PDF]  

Malgorzata Tokarska-Schlattner, Theo Wallimann, and Uwe Schlattner
Multiple Interference of Anthracyclines with Mitochondrial Creatine Kinases: Preferential Damage of the Cardiac Isoenzyme and Its Implications for Drug Cardiotoxicity
Mol Pharmacol 2002 61: 516-523. [Abstract] [Full Text] [PDF]  

Donatella Del Bufalo, Valeriana Di Castro, Annamaria Biroccio, Marco Varmi, Debora Salani, Laura Rosanò, Daniela Trisciuoglio, Francesca Spinella, and Anna Bagnato
Endothelin-1 Protects Ovarian Carcinoma Cells against Paclitaxel-Induced Apoptosis: Requirement for Akt Activation
Mol Pharmacol 2002 61: 524-532. [Abstract] [Full Text] [PDF]  

Keiko Kashiwagi, Takashi Masuko, Christopher D. Nguyen, Tomoko Kuno, Ikuko Tanaka, Kazuei Igarashi, and Keith Williams
Channel Blockers Acting at N-Methyl-D-aspartate Receptors: Differential Effects of Mutations in the Vestibule and Ion Channel Pore
Mol Pharmacol 2002 61: 533-545. [Abstract] [Full Text] [PDF]  

Thierry Sabourin, Luc Bastien, Dimcho R. Bachvarov, and François Marceau
Agonist-Induced Translocation of the Kinin B1 Receptor to Caveolae-Related Rafts
Mol Pharmacol 2002 61: 546-553. [Abstract] [Full Text] [PDF]  

G. Scapagnini, R. Foresti, V. Calabrese, A. M. Giuffrida Stella, C. J. Green, and R. Motterlini
Caffeic Acid Phenethyl Ester and Curcumin: A Novel Class of Heme Oxygenase-1 Inducers
Mol Pharmacol 2002 61: 554-561. [Abstract] [Full Text] [PDF]  

Helen Brady, Mary Doubleday, Leah M. Gayo-Fung, Matt Hickman, Sak Khammungkhune, Adam Kois, Stephanie Lipps, Steve Pierce, Normand Richard, Graciella Shevlin, May Kung Sutherland, David W. Anderson, Shripad S. Bhagwat, and Bernd Stein
Differential Response of Estrogen Receptors alpha and beta to SP500263, a Novel Potent Selective Estrogen Receptor Modulator
Mol Pharmacol 2002 61: 562-568. [Abstract] [Full Text] [PDF]  

Min Huang, Piotr Kozlowski, Matthew Collins, Yanhong Wang, Timothy A. Haystead, and Lee M. Graves
Caspase-Dependent Cleavage of Carbamoyl Phosphate Synthetase II during Apoptosis
Mol Pharmacol 2002 61: 569-577. [Abstract] [Full Text] [PDF]  

Chiung-Chun Huang, Yea-Lin Chen, Shiow-Win Lo, and Kuei-Sen Hsu
Activation of cAMP-Dependent Protein Kinase Suppresses the Presynaptic Cannabinoid Inhibition of Glutamatergic Transmission at Corticostriatal Synapses
Mol Pharmacol 2002 61: 578-585. [Abstract] [Full Text] [PDF]  

Eleni Aklillu, Mikael Oscarson, Mats Hidestrand, Brith Leidvik, Charlotta Otter, and Magnus Ingelman-Sundberg
Functional Analysis of Six Different Polymorphic CYP1B1 Enzyme Variants Found in an Ethiopian Population
Mol Pharmacol 2002 61: 586-594. [Abstract] [Full Text] [PDF]  

Bryce Vissel, Johannes J. Krupp, Stephen F. Heinemann, and Gary L. Westbrook
Intracellular Domains of NR2 Alter Calcium-Dependent Inactivation of N-Methyl-D-aspartate Receptors
Mol Pharmacol 2002 61: 595-605. [Abstract] [Full Text] [PDF]  

Isao Matsuoka, Satoko Ohkubo, Junko Kimura, and Yasuhito Uezono
Adenine Nucleotide-Induced Activation of Adenosine A2B Receptors Expressed in Xenopus laevis Oocytes: Involvement of a Rapid and Localized Adenosine Formation by Ectonucleotidases
Mol Pharmacol 2002 61: 606-613. [Abstract] [Full Text] [PDF]  

Dae-Won Park, Yoe-Sik Bae, Ju-Ock Nam, Jong-Ho Kim, Young-Gi Lee, Yoon-Ki Park, Sung Ho Ryu, and Suk-Hwan Baek
Regulation of Cyclooxygenase-2 Expression by Phospholipase D in Human Amnion-Derived WISH Cells
Mol Pharmacol 2002 61: 614-619. [Abstract] [Full Text] [PDF]  

Tadakazu Kondo, Yoshiko Suzuki, Toshiyuki Kitano, Kazuya Iwai, Mitsumasa Watanabe, Hisanori Umehara, Naoharu Daido, Naochika Domae, Masaro Tashima, Takashi Uchiyama, and Toshiro Okazaki
Vesnarinone Causes Oxidative Damage by Inhibiting Catalase Function through Ceramide Action in Myeloid Cell Apoptosis
Mol Pharmacol 2002 61: 620-627. [Abstract] [Full Text] [PDF]  

Evelyn Breitweg-Lehmann, Cornelia Czupalla, Rüdiger Storm, Oliver Kudlacek, Walter Schunack, Michael Freissmuth, and Bernd Nürnberg
Activation and Inhibition of G Proteins by Lipoamines
Mol Pharmacol 2002 61: 628-636. [Abstract] [Full Text] [PDF]  

Gerhard F. Ecker, Edina Csaszar, Stephan Kopp, Brigitte Plagens, Wolfgang Holzer, Wolfgang Ernst, and Peter Chiba
Identification of Ligand-Binding Regions of P-Glycoprotein by Activated-Pharmacophore Photoaffinity Labeling and Matrix-Assisted Laser Desorption/Ionization-Time-of-Flight Mass Spectrometry
Mol Pharmacol 2002 61: 637-648. [Abstract] [Full Text] [PDF]  

P. Phani Kumar, Stephanie C. Stotz, R. Paramashivappa, Aaron M. Beedle, Gerald W. Zamponi, and A. Srinivasa Rao
Synthesis and Evaluation of a New Class of Nifedipine Analogs with T-Type Calcium Channel Blocking Activity
Mol Pharmacol 2002 61: 649-658. [Abstract] [Full Text] [PDF]  

Paul W. Schenk, Antonius W. M. Boersma, Mariël Brok, Herman Burger, Gerrit Stoter, and Kees Nooter
Inactivation of the Saccharomyces cerevisiae SKY1 Gene Induces a Specific Modification of the Yeast Anticancer Drug Sensitivity Profile Accompanied by a Mutator Phenotype
Mol Pharmacol 2002 61: 659-666. [Abstract] [Full Text] [PDF]  

Yoshihiro Kimura and Makoto Inui
Reconstitution of the Cytoplasmic Interaction between Phospholamban and Ca2+-ATPase of Cardiac Sarcoplasmic Reticulum
Mol Pharmacol 2002 61: 667-673. [Abstract] [Full Text] [PDF]  

Susan W. Robinson, Bruce Clothier, Ruth A. Akhtar, Ai Li Yang, Isabelle Latour, Carola Van Ijperen, Michael F. W. Festing, and Andrew G. Smith
Non-Ahr Gene Susceptibility Loci for Porphyria and Liver Injury Induced by the Interaction of `Dioxin' with Iron Overload in Mice
Mol Pharmacol 2002 61: 674-681. [Abstract] [Full Text] [PDF]  

Guido Michels, Jan Matthes, Renate Handrock, Ute Kuchinke, Ferdi Groner, Leanne L. Cribbs, Alexey Pereverzev, Toni Schneider, Edward Perez-Reyes, and Stefan Herzig
Single-Channel Pharmacology of Mibefradil in Human Native T-Type and Recombinant Cav3.2 Calcium Channels
Mol Pharmacol 2002 61: 682-694. [Abstract] [Full Text] [PDF]  

Ron S. Broide, Ramiro Salas, Daoyun Ji, Richard Paylor, James W. Patrick, John A. Dani, and Mariella De Biasi
Increased Sensitivity to Nicotine-Induced Seizures in Mice Expressing the L250T alpha 7 Nicotinic Acetylcholine Receptor Mutation
Mol Pharmacol 2002 61: 695-705. [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

About the cover: Three-dimensional molecular representation of the distribution of positively charge residues in rhodopsin. The Calpha trace of rhodopsin (yellow) is viewed perpendicular to the transmembrane domain axis, with the extracellular side on the top and the intracellular side on the bottom. The side chains of Arg and Lys are shownin blue sticks. To represent the membrane bilayer, several phospholipid molecules (phosphatidylcholines in the extracellular leaflet and negatively charged phosphatidylserines in the cytoplasmic leaflet) are shown. Mol Pharmacol 60:1-19.



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