Accelerated Communications:

Yumiko Ishizawa, Ravindernath Pidikiti, Paul A. Liebman, and Roderic G. Eckenhoff

G Protein-Coupled Receptors as Direct Targets of Inhaled Anesthetics
Mol Pharmacol 2002 61: 945-952. [Abstract] [Full Text] [PDF]  

Articles:

Maeve Sheehan, Hector R. Wong, Paul W. Hake, Vivek Malhotra, Michael O'Connor, and Basilia Zingarelli

Parthenolide, an Inhibitor of the Nuclear Factor-B Pathway, Ameliorates Cardiovascular Derangement and Outcome in Endotoxic Shock in Rodents
Mol Pharmacol 2002 61: 953-963. [Abstract] [Full Text] [PDF]  

Sean Ekins, Richard B. Kim, Brenda F. Leake, Anne H. Dantzig, Erin G. Schuetz, Lu-Bin Lan, Kazuto Yasuda, Robert L. Shepard, Mark A. Winter, John D. Schuetz, James H. Wikel, and Steven A. Wrighton

Three-Dimensional Quantitative Structure-Activity Relationships of Inhibitors of P-Glycoprotein
Mol Pharmacol 2002 61: 964-973. [Abstract] [Full Text] [PDF]  

Sean Ekins, Richard B. Kim, Brenda F. Leake, Anne H. Dantzig, Erin G. Schuetz, Lu-Bin Lan, Kazuto Yasuda, Robert L. Shepard, Mark a Winter, John D. Schuetz, James H. Wikel, and Steven A. Wrighton

Application of Three-Dimensional Quantitative Structure-Activity Relationships of P-Glycoprotein Inhibitors and Substrates
Mol Pharmacol 2002 61: 974-981. [Abstract] [Full Text] [PDF]  

Yoshinori Nagata, Hiroyuki Kusuhara, Hitoshi Endou, and Yuichi Sugiyama

Expression and Functional Characterization of Rat Organic Anion Transporter 3 (rOat3) in the Choroid Plexus
Mol Pharmacol 2002 61: 982-988. [Abstract] [Full Text] [PDF]  

S. Chiechio, A. Caricasole, E. Barletta, M. Storto, M. V. Catania, A. Copani, M. Vertechy, R. Nicolai, M. Calvani, D. Melchiorri, and F. Nicoletti

L-Acetylcarnitine Induces Analgesia by Selectively Up-Regulating mGlu2 Metabotropic Glutamate Receptors
Mol Pharmacol 2002 61: 989-996. [Abstract] [Full Text] [PDF]  

Salvatore Cuzzocrea, Nicole S. Wayman, Emanuela Mazzon, Laura Dugo, Rosanna Di Paola, Ivana Serraino, Domenico Britti, Prabal K. Chatterjee, Achille P. Caputi, and Christoph Thiemermann

The Cyclopentenone Prostaglandin 15-Deoxy-^12,14-Prostaglandin J₂ Attenuates the Development of Acute and Chronic Inflammation
Mol Pharmacol 2002 61: 997-1007. [Abstract] [Full Text] [PDF]  

Dan Chalothorn, Dan F. McCune, Stephanie E. Edelmann, Mary L. García-Cazarín, Gozoh Tsujimoto, and Michael T. Piascik

Differences in the Cellular Localization and Agonist-Mediated Internalization Properties of the ₁-Adrenoceptor Subtypes
Mol Pharmacol 2002 61: 1008-1016. [Abstract] [Full Text] [PDF]  

Alessandra Mallei, Bitao Shi, and Italo Mocchetti

Antidepressant Treatments Induce the Expression of Basic Fibroblast Growth Factor in Cortical and Hippocampal Neurons
Mol Pharmacol 2002 61: 1017-1024. [Abstract] [Full Text] [PDF]  

Peter J. Greasley, Francesca Fanelli, Olivier Rossier, Liliane Abuin, and Susanna Cotecchia

Mutagenesis and Modelling of the _1b-Adrenergic Receptor Highlight the Role of the Helix 3/Helix 6 Interface in Receptor Activation
Mol Pharmacol 2002 61: 1025-1032. [Abstract] [Full Text] [PDF]  

Heather A. Dunkerley, Douglas G. Tilley, Daniel Palmer, Hanguan Liu, Sandra L. Jimmo, and Donald H. Maurice

Reduced Phosphodiesterase 3 Activity and Phosphodiesterase 3A Level in Synthetic Vascular Smooth Muscle Cells: Implications for Use of Phosphodiesterase 3 Inhibitors in Cardiovascular Tissues
Mol Pharmacol 2002 61: 1033-1040. [Abstract] [Full Text] [PDF]  

Xi-Qin Ding, Delia I. Pinon, Kristina E. Furse, Terry P. Lybrand, and Laurence J. Miller

Refinement of the Conformation of a Critical Region of Charge-Charge Interaction between Cholecystokinin and Its Receptor
Mol Pharmacol 2002 61: 1041-1052. [Abstract] [Full Text] [PDF]  

Richard A. Hughes, Trudi Harris, Emile Altmann, David McAllister, Ross Vlahos, Alan Robertson, Mark Cushman, Zhiqiang Wang, and Alastair G. Stewart

2-Methoxyestradiol and Analogs as Novel Antiproliferative Agents: Analysis of Three-Dimensional Quantitative Structure-Activity Relationships for DNA Synthesis Inhibition and Estrogen Receptor Binding
Mol Pharmacol 2002 61: 1053-1069. [Abstract] [Full Text] [PDF]  

Sylvia Grünewald, Bettina J. Schupp, Stephen R. Ikeda, Rohini Kuner, Frank Steigerwald, Hans-Christian Kornau, and Georg Köhr

Importance of the -Aminobutyric Acid_B Receptor C-Termini for G-Protein Coupling
Mol Pharmacol 2002 61: 1070-1080. [Abstract] [Full Text] [PDF]  

Achim Lass, Astrid Suessenbacher, Gerald Wölkart, Bernd Mayer, and Friedrich Brunner

Functional and Analytical Evidence for Scavenging of Oxygen Radicals by L-Arginine
Mol Pharmacol 2002 61: 1081-1088. [Abstract] [Full Text] [PDF]  

Dongxu Liu and David J. Waxman

Post-Transcriptional Regulation of Hepatic NADPH-Cytochrome P450 Reductase by Thyroid Hormone: Independent Effects on Poly(A) Tail Length and mRNA Stability
Mol Pharmacol 2002 61: 1089-1096. [Abstract] [Full Text] [PDF]  

Samuel H. H. Chan, Kui-Fen Chang, Chen-Chun Ou, and Julie Y. H. Chan

Up-Regulation of Glutamate Receptors in Nucleus Tractus Solitarii Underlies Potentiation of Baroreceptor Reflex by Heat Shock Protein 70
Mol Pharmacol 2002 61: 1097-1104. [Abstract] [Full Text] [PDF]  

Gregory M. Dick, A. Christy Hunter, and Kenton M. Sanders

Ethylbromide Tamoxifen, a Membrane-Impermeant Antiestrogen, Activates Smooth Muscle Calcium-Activated Large-Conductance Potassium Channels from the Extracellular Side
Mol Pharmacol 2002 61: 1105-1113. [Abstract] [Full Text] [PDF]  

Stuart J. Mundell, Anne-Lise Matharu, Giordano Pula, David Holman, Peter J. Roberts, and Eamonn Kelly

Metabotropic Glutamate Receptor 1 Internalization Induced by Muscarinic Acetylcholine Receptor Activation: Differential Dependency of Internalization of Splice Variants on Nonvisual Arrestins
Mol Pharmacol 2002 61: 1114-1123. [Abstract] [Full Text] [PDF]  

Subramaniam Jayanthi, Michael T. McCoy, Bruce Ladenheim, and Jean Lud Cadet

Methamphetamine Causes Coordinate Regulation of Src, Cas, Crk, and the Jun N-Terminal Kinase-Jun Pathway
Mol Pharmacol 2002 61: 1124-1131. [Abstract] [Full Text] [PDF]  

Frank M. Dautzenberg, Jacqueline Higelin, Olaf Brauns, Brigitte Butscha, and Richard L. Hauger

Five Amino Acids of the Xenopus laevis CRF (Corticotropin-Releasing Factor) Type 2 Receptor Mediate Differential Binding of CRF Ligands in Comparison with Its Human Counterpart
Mol Pharmacol 2002 61: 1132-1139. [Abstract] [Full Text] [PDF]  

Jan Balzarini, Rebecca Sienaert, Sandra Liekens, André Van Kuilenburg, Antonella Carangio, Robert Esnouf, Erik De Clercq, and Chris McGuigan

Lack of Susceptibility of Bicyclic Nucleoside Analogs, Highly Potent Inhibitors of Varicella-Zoster Virus, to the Catabolic Action of Thymidine Phosphorylase and Dihydropyrimidine Dehydrogenase
Mol Pharmacol 2002 61: 1140-1145. [Abstract] [Full Text] [PDF]  

Bernard P. Murray, Victor G. Zgoda, and Maria Almira Correia

Native CYP2C11: Heterologous Expression in Saccharomyces cerevisiae Reveals a Role for Vacuolar Proteases Rather Than the Proteasome System in the Degradation of This Endoplasmic Reticulum Protein
Mol Pharmacol 2002 61: 1146-1153. [Abstract] [Full Text] [PDF]  

Sharon M. Gowan, John R. Harrison, Lisa Patterson, Melanie Valenti, Martin A. Read, Stephen Neidle, and Lloyd R. Kelland

A G-Quadruplex-Interactive Potent Small-Molecule Inhibitor of Telomerase Exhibiting in Vitro and in Vivo Antitumor Activity
Mol Pharmacol 2002 61: 1154-1162. [Abstract] [Full Text] [PDF]  

Rong-Sen Yang, Chih-Hsin Tang, Qing-Dong Ling, Shing-Hwa Liu, and Wen-Mei Fu

Regulation of Fibronectin Fibrillogenesis by Protein Kinases in Cultured Rat Osteoblasts
Mol Pharmacol 2002 61: 1163-1173. [Abstract] [Full Text] [PDF]  

M. T. Holderman, K. P. Miller, L. J. Dangott, and K. S. Ramos

Identification of Albumin Precursor Protein, Phi AP3, and -Smooth Muscle Actin as Novel Components of Redox Sensing Machinery in Vascular Smooth Muscle Cells
Mol Pharmacol 2002 61: 1174-1183. [Abstract] [Full Text] [PDF]  

Ki Churl Chang, Kyung Shin Paek, Hyo Jung Kim, Young Soo Lee, Chihiro Yabe-Nishimura, and Han Geuk Seo

Substrate-Induced Up-Regulation of Aldose Reductase by Methylglyoxal, a Reactive Oxoaldehyde Elevated in Diabetes
Mol Pharmacol 2002 61: 1184-1191. [Abstract] [Full Text] [PDF]  

Theodore R. Cummins, Fabio Aglieco, and Sulayman D. Dib-Hajj

Critical Molecular Determinants of Voltage-Gated Sodium Channel Sensitivity to µ-Conotoxins GIIIA/B
Mol Pharmacol 2002 61: 1192-1201. [Abstract] [Full Text] [PDF]  

Jeremiah Stitham, Kathleen A. Martin, and John Hwa

The Critical Role of Transmembrane Prolines in Human Prostacyclin Receptor Activation
Mol Pharmacol 2002 61: 1202-1210. [Abstract] [Full Text] [PDF]  

Philip J. Welsby, Elaine Kellett, Graeme Wilkinson, and Graeme Milligan

Enhanced Detection of Receptor Constitutive Activity in the Presence of Regulators of G Protein Signaling: Applications to the Detection and Analysis of Inverse Agonists and Low-Efficacy Partial Agonists
Mol Pharmacol 2002 61: 1211-1221. [Abstract] [Full Text] [PDF]  

Máriton D. Santos, Manickavasagom Alkondon, Edna F. R. Pereira, Yasco Aracava, Howard M. Eisenberg, Alfred Maelicke, and Edson X. Albuquerque

The Nicotinic Allosteric Potentiating Ligand Galantamine Facilitates Synaptic Transmission in the Mammalian Central Nervous System
Mol Pharmacol 2002 61: 1222-1234. [Abstract] [Full Text] [PDF]  

Lars H. Jensen, Axelle Renodon-Corniere, Irene Wessel, Seppo W. Langer, Birgitte Søkilde, Elisabeth V. Carstensen, Maxwell Sehested, and Peter B. Jensen

Maleimide Is a Potent Inhibitor of Topoisomerase II in Vitro and in Vivo: A New Mode of Catalytic Inhibition
Mol Pharmacol 2002 61: 1235-1243. [Abstract] [Full Text] [PDF]  

Hilde Lavreysen, Emmanuel Le Poul, Paul Van Gompel, Lieve Dillen, Josée E. Leysen, and Anne S. J. Lesage

Supersensitivity of Human Metabotropic Glutamate 1a Receptor Signaling in L929sA Cells
Mol Pharmacol 2002 61: 1244-1254. [Abstract] [Full Text] [PDF]  

Petri P. Lehenkari, Maarit Kellinsalmi, Juha P. Näpänkangas, Kari V. Ylitalo, Jukka Mönkkönen, Michael J. Rogers, Alex Azhayev, H. Kalervo Väänänen, and Ilmo E. Hassinen

Further Insight into Mechanism of Action of Clodronate: Inhibition of Mitochondrial ADP/ATP Translocase by a Nonhydrolyzable, Adenine-Containing Metabolite
Mol Pharmacol 2002 61: 1255-1262. [Abstract] [Full Text] [PDF]  

Errata:

Correction to "Antitumor Activity of 2',3'-Dideoxycytidine Nucleotide Analog Against Tumors Up-Regulating DNA Polymerase "
Mol Pharmacol 2002 61: 1263. [Full Text] [PDF]  

Correction to "Caffeic Acid Phenethyl Ester and Curcumin: A Novel Class of Heme Oxygenase-1 Inducers"
Mol Pharmacol 2002 61: 1264. [Full Text] [PDF]  

Correction to "Novel "Nonkinase" Phorbol Ester Receptors: The C1 Domain Connection"
Mol Pharmacol 2002 61: 1265. [Full Text] [PDF]  

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