Mol Pharm -- Table of Contents (61 [6])

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June 2002; 61 (6)   [Index by Author] [Cover Caption]

       Accelerated Communications

       Articles

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Accelerated Communications:

Alena Krej $c$ í and Stanislav Tu $c$ ek: Quantitation of mRNAs for M₁ to M₅ Subtypes of Muscarinic Receptors in Rat Heart and Brain Cortex
Mol Pharmacol 2002 61: 1267-1272. [Abstract] [Full Text] [PDF]

Articles:

Tomas Barkhem, Lars-Arne Haldosén, Jan-Åke Gustafsson, and Stefan Nilsson: pS2 Gene Expression in HepG2 cells: Complex Regulation through Crosstalk between the Estrogen Receptor $alpha$ , an Estrogen-Responsive Element, and the Activator Protein 1 Response Element
Mol Pharmacol 2002 61: 1273-1283. [Abstract] [Full Text] [PDF]

Akiko Ueda, Satoru Kakizaki, Masahiko Negishi, and Tatsuya Sueyoshi: Residue Threonine 350 Confers Steroid Hormone Responsiveness to the Mouse Nuclear Orphan Receptor CAR
Mol Pharmacol 2002 61: 1284-1288. [Abstract] [Full Text] [PDF]

Hitomi Takanaga, Noriyo Tokuda, Sumio Ohtsuki, Ken-ichi Hosoya, and Tetsuya Terasaki: ATA2 Is Predominantly Expressed as System A at the Blood-Brain Barrier and Acts as Brain-to-Blood Efflux Transport for L-Proline
Mol Pharmacol 2002 61: 1289-1296. [Abstract] [Full Text] [PDF]

Tracy A. Spalding, Carol Trotter, Niels Skjærbæk, Terri L. Messier, Erika A. Currier, Ethan S. Burstein, Donghui Li, Uli Hacksell, and Mark R. Brann: Discovery of an Ectopic Activation Site on the M₁ Muscarinic Receptor
Mol Pharmacol 2002 61: 1297-1302. [Abstract] [Full Text] [PDF]

Scott D. Sorensen, Thomas A. Macek, Zhaohui Cai, Julie A. Saugstad, and P. Jeffrey Conn: Dissociation of Protein Kinase-Mediated Regulation of Metabotropic Glutamate Receptor 7 (mGluR7) Interactions with Calmodulin and Regulation of mGluR7 Function
Mol Pharmacol 2002 61: 1303-1312. [Abstract] [Full Text] [PDF]

L. Cartee, R. Smith, Y. Dai, M. Rahmani, R. Rosato, J. Almenara, P. Dent, and S. Grant: Synergistic Induction of Apoptosis in Human Myeloid Leukemia Cells by Phorbol 12-Myristate 13-Acetate and Flavopiridol Proceeds via Activation of Both the Intrinsic and Tumor Necrosis Factor-Mediated Extrinsic Cell Death Pathways
Mol Pharmacol 2002 61: 1313-1321. [Abstract] [Full Text] [PDF]

Janet L. Fisher: Amiloride Inhibition of $gamma$ -Aminobutyric Acid_A Receptors Depends upon the $alpha$ Subunit Subtype
Mol Pharmacol 2002 61: 1322-1328. [Abstract] [Full Text] [PDF]

Melanija Tomi $c'$ , Fredrick Van Goor, Mu-Lan He, Dragoslava Zivadinovic, and Stanko S. Stojilkovic: Ca²⁺-Mobilizing Endothelin-A Receptors Inhibit Voltage-Gated Ca²⁺ Influx through G_i/o Signaling Pathway in Pituitary Lactotrophs
Mol Pharmacol 2002 61: 1329-1339. [Abstract] [Full Text] [PDF]

Manjula Mahata, Nitish R. Mahapatra, Daniel T. O'Connor, and Sushil K. Mahata: Chromaffin Cell Catecholamine Secretion: Bisindolylmaleimide Compounds Exhibit Novel and Potent Antagonist Effects at the Nicotinic Cholinergic Receptor in Pheochromocytoma Cells
Mol Pharmacol 2002 61: 1340-1347. [Abstract] [Full Text] [PDF]

David M. Smith, Aslamuzzaman Kazi, Lisa Smith, Timothy E. Long, Bart Heldreth, Edward Turos, and Q. Ping Dou: A Novel $beta$ -Lactam Antibiotic Activates Tumor Cell Apoptotic Program by Inducing DNA Damage
Mol Pharmacol 2002 61: 1348-1358. [Abstract] [Full Text] [PDF]

Xin Wang, Hiroshi Miyake, Mika Okamoto, Mineki Saito, Jun-Ichi Fujisawa, Yuetsu Tanaka, Shuji Izumo, and Masanori Baba: Inhibition of the Tax-Dependent Human T-Lymphotropic Virus Type I Replication in Persistently Infected Cells by the Fluoroquinolone Derivative K-37
Mol Pharmacol 2002 61: 1359-1365. [Abstract] [Full Text] [PDF]

Christoph Borchers, Rainer Boer, Kurt Klemm, Volker Figala, Thomas Denzinger, Wolf-Rüdiger Ulrich, Sabine Haas, Wolfgang Ise, Volker Gekeler, and Michael Przybylski: Characterization of the Dexniguldipine Binding Site in the Multidrug Resistance-Related Transport Protein P-Glycoprotein by Photoaffinity Labeling and Mass Spectrometry
Mol Pharmacol 2002 61: 1366-1376. [Abstract] [Full Text] [PDF]

Anders A. Jensen, Johannes Mosbacher, Susanne Elg, Kurt Lingenhoehl, Tania Lohmann, Tommy N. Johansen, Bjarke Abrahamsen, Jan P. Mattsson, Anders Lehmann, Bernhard Bettler, and Hans Bräuner-Osborne: The Anticonvulsant Gabapentin (Neurontin) Does Not Act through $gamma$ -Aminobutyric Acid-B Receptors
Mol Pharmacol 2002 61: 1377-1384. [Abstract] [Full Text] [PDF]

T. C. Tai, R. Claycomb, S. Her, A. K. Bloom, and Dona L. Wong: Glucocorticoid Responsiveness of the Rat Phenylethanolamine N-Methyltransferase Gene
Mol Pharmacol 2002 61: 1385-1392. [Abstract] [Full Text] [PDF]

Jane M. Rogers and Michael S. Denison: Analysis of the Antiestrogenic Activity of 2,3,7,8-Tetrachlorodibenzo-p-dioxin in Human Ovarian Carcinoma BG-1 Cells
Mol Pharmacol 2002 61: 1393-1403. [Abstract] [Full Text] [PDF]

Kwang-Lae Hoe and Juan M. Saavedra: Site-Directed Mutagenesis of the Gerbil and Human Angiotensin II AT₁ Receptors Identifies Amino Acid Residues Attributable to the Binding Affinity for the Nonpeptidic Antagonist Losartan
Mol Pharmacol 2002 61: 1404-1415. [Abstract] [Full Text] [PDF]

Ray Rush, Alexander Kuryatov, Mark E. Nelson, and Jon Lindstrom: First and Second Transmembrane Segments of $alpha$ 3, $alpha$ 4, $beta$ 2, and $beta$ 4 Nicotinic Acetylcholine Receptor Subunits Influence the Efficacy and Potency of Nicotine
Mol Pharmacol 2002 61: 1416-1422. [Abstract] [Full Text] [PDF]

Yasuko Ishikawa, Hirokazu Iida, and Hajime Ishida: The Muscarinic Acetylcholine Receptor-Stimulated Increase in Aquaporin-5 Levels in the Apical Plasma Membrane in Rat Parotid Acinar Cells Is Coupled with Activation of Nitric Oxide/cGMP Signal Transduction
Mol Pharmacol 2002 61: 1423-1434. [Abstract] [Full Text] [PDF]

Kenji Tokita, Simon J. Hocart, David H. Coy, and Robert T. Jensen: Molecular Basis of the Selectivity of Gastrin-Releasing Peptide Receptor for Gastrin-Releasing Peptide
Mol Pharmacol 2002 61: 1435-1443. [Abstract] [Full Text] [PDF]

Rüdiger Schulz, Andrea Wehmeyer, and Karin Schulz: Visualizing Preference of G Protein-Coupled Receptor Kinase 3 for the Process of $kappa$ -Opioid Receptor Sequestration
Mol Pharmacol 2002 61: 1444-1452. [Abstract] [Full Text] [PDF]

Norio Sakai, Johannes Thome, Samuel S. Newton, Jingshan Chen, Max B. Kelz, Cathy Steffen, Eric J. Nestler, and Ronald S. Duman: Inducible and Brain Region-Specific CREB Transgenic Mice
Mol Pharmacol 2002 61: 1453-1464. [Abstract] [Full Text] [PDF]

Maris Lapinsh, Peteris Prusis, Torbjörn Lundstedt, and Jarl E. S. Wikberg: Proteochemometrics Modeling of the Interaction of Amine G-Protein Coupled Receptors with a Diverse Set of Ligands
Mol Pharmacol 2002 61: 1465-1475. [Abstract] [Full Text] [PDF]

Theresa C. Peterson, Marc R. Peterson, Harold A. Robertson, Matthew During, and Michael Dragunow: Selective Down-Regulation of c-jun Gene Expression by Pentoxifylline and c-jun Antisense Interrupts Platelet-Derived Growth Factor Signaling: Pentoxifylline Inhibits Phosphorylation of c-Jun on Serine 73
Mol Pharmacol 2002 61: 1476-1488. [Abstract] [Full Text] [PDF]

Deepak Raina, Neerad Mishra, Shailendra Kumar, Surender Kharbanda, Satya Saxena, and Donald Kufe: Inhibition of c-Abl with STI571 Attenuates Stress-Activated Protein Kinase Activation and Apoptosis in the Cellular Response to 1- $beta$ -D-Arabinofuranosylcytosine
Mol Pharmacol 2002 61: 1489-1495. [Abstract] [Full Text] [PDF]

Cover Caption:

About the cover: Three-dimensional molecular representation of the distribution of positively charge residues in rhodopsin.The C $alpha$ trace of rhodopsin (yellow) is viewed perpendicular tothe transmembrane domain axis, with the extracellular side onthe top and the intracellular side on the bottom. The side chainsof Arg and Lys are shownin blue sticks. To represent the membranebilayer, several phospholipid molecules (phosphatidylcholinesin the extracellular leaflet and negatively charged phosphatidylserinesin the cytoplasmic leaflet) are shown. Mol Pharmacol 60:1-19.