Perspective:

Joel Linden

Autoregulation of Cyclic AMP in Vascular Smooth Muscle: A Role for Adenosine Receptors
Mol Pharmacol 2002 62: 969-970. [Full Text] [PDF]  

Robert J. Lefkowitz, Kristen L. Pierce, and Louis M. Luttrell

Dancing with Different Partners: Protein Kinase A Phosphorylation of Seven Membrane-Spanning Receptors Regulates Their G Protein-Coupling Specificity
Mol Pharmacol 2002 62: 971-974. [Full Text] [PDF]  

Articles:

Eunseon Hur, Hong-Hee Kim, Su Mi Choi, Jin Hee Kim, Sujin Yim, Ho Jeong Kwon, Youngyeon Choi, Dae Kyong Kim, Mi-Ock Lee, and Hyunsung Park

Reduction of Hypoxia-Induced Transcription through the Repression of Hypoxia-Inducible Factor-1/Aryl Hydrocarbon Receptor Nuclear Translocator DNA Binding by the 90-kDa Heat-Shock Protein Inhibitor Radicicol
Mol Pharmacol 2002 62: 975-982. [Abstract] [Full Text] [PDF]  

Rennolds S. Ostrom, Xiaoqiu Liu, Brian P. Head, Caroline Gregorian, Tammy M. Seasholtz, and Paul A. Insel

Localization of Adenylyl Cyclase Isoforms and G Protein-Coupled Receptors in Vascular Smooth Muscle Cells: Expression in Caveolin-Rich and Noncaveolin Domains
Mol Pharmacol 2002 62: 983-992. [Abstract] [Full Text] [PDF]  

Xiaolin Deng, Subramaniam Jayanthi, Bruce Ladenheim, Irina N. Krasnova, and Jean Lud Cadet

Mice with Partial Deficiency of c-Jun Show Attenuation of Methamphetamine-Induced Neuronal Apoptosis
Mol Pharmacol 2002 62: 993-1000. [Abstract] [Full Text] [PDF]  

Keon Wook Kang, Seung Jin Lee, Jeong Weon Park, and Sang Geon Kim

Phosphatidylinositol 3-Kinase Regulates Nuclear Translocation of NF-E2-Related Factor 2 through Actin Rearrangement in Response to Oxidative Stress
Mol Pharmacol 2002 62: 1001-1010. [Abstract] [Full Text] [PDF]  

Tarang Manchanda, David Hess, Lianna Dale, Stephen G. Ferguson, and Michael J. Rieder

Haptenation of Sulfonamide Reactive Metabolites to Cellular Proteins
Mol Pharmacol 2002 62: 1011-1026. [Abstract] [Full Text] [PDF]  

Marcello Maggiolini, Adele Vivacqua, Amalia Carpino, Daniela Bonofiglio, Giovanna Fasanella, Michele Salerno, Didier Picard, and Sebastiano Andó

The Mutant Androgen Receptor T877A Mediates the Proliferative but Not the Cytotoxic Dose-Dependent Effects of Genistein and Quercetin on Human LNCaP Prostate Cancer Cells
Mol Pharmacol 2002 62: 1027-1035. [Abstract] [Full Text] [PDF]  

Haim Tsubery, Itzhak Ofek, Sofia Cohen, Miriam Eisenstein, and Mati Fridkin

Modulation of the Hydrophobic Domain of Polymyxin B Nonapeptide: Effect on Outer-Membrane Permeabilization and Lipopolysaccharide Neutralization
Mol Pharmacol 2002 62: 1036-1042. [Abstract] [Full Text] [PDF]  

Jean-Denis Troadec, Marc Marien, Sophie Mourlevat, Thomas Debeir, Merle Ruberg, Francis Colpaert, and Patrick P. Michel

Activation of the Mitogen-Activated Protein Kinase (ERK_1/2) Signaling Pathway by Cyclic AMP Potentiates the Neuroprotective Effect of the Neurotransmitter Noradrenaline on Dopaminergic Neurons
Mol Pharmacol 2002 62: 1043-1052. [Abstract] [Full Text] [PDF]  

Michael F. Wilkemeyer, Carrie E. Menkari, and Michael E. Charness

Novel Antagonists of Alcohol Inhibition of L1-Mediated Cell Adhesion: Multiple Mechanisms of Action
Mol Pharmacol 2002 62: 1053-1060. [Abstract] [Full Text] [PDF]  

Ralf Peter Meyer, Michael Podvinec, and Urs A. Meyer

Cytochrome P450 CYP1A1 Accumulates in the Cytosol of Kidney and Brain and Is Activated by Heme
Mol Pharmacol 2002 62: 1061-1067. [Abstract] [Full Text] [PDF]  

Belén Ramos, Mohammed El Mouedden, Enrique Claro, and Suzanne Jackowski

Inhibition of CTP:Phosphocholine Cytidylyltransferase by C₂-Ceramide and Its Relationship to Apoptosis
Mol Pharmacol 2002 62: 1068-1075. [Abstract] [Full Text] [PDF]  

Tong Lu, Mike VanRollins, and Hon-Chi Lee

Stereospecific Activation of Cardiac ATP-Sensitive K⁺ Channels by Epoxyeicosatrienoic Acids: A Structural Determinant Study
Mol Pharmacol 2002 62: 1076-1083. [Abstract] [Full Text] [PDF]  

Alokesh Duttaroy, Jesus Gomeza, Jai-Wei Gan, Nasir Siddiqui, Anthony S. Basile, W. Dean Harman, Philip L. Smith, Christian C. Felder, Allan I. Levey, and Jürgen Wess

Evaluation of Muscarinic Agonist-Induced Analgesia in Muscarinic Acetylcholine Receptor Knockout Mice
Mol Pharmacol 2002 62: 1084-1093. [Abstract] [Full Text] [PDF]  

Jacqueline Friedman, Bonita Babu, and Richard B. Clark

₂-Adrenergic Receptor Lacking the Cyclic AMP-Dependent Protein Kinase Consensus Sites Fully Activates Extracellular Signal-Regulated Kinase 1/2 in Human Embryonic Kidney 293 Cells: Lack of Evidence for G_s/G_i Switching.
Mol Pharmacol 2002 62: 1094-1102. [Abstract] [Full Text] [PDF]  

Friederike Stoll, Sven Liesener, Thomas Hohlfeld, Karsten Schrör, Philip L. Fuchs, and Hans-Dieter Höltje

Pharmacophore Definition and Three-Dimensional Quantitative Structure-Activity Relationship Study on Structurally Diverse Prostacyclin Receptor Agonists
Mol Pharmacol 2002 62: 1103-1111. [Abstract] [Full Text] [PDF]  

Yong-Dae Kim, Eun-Jin Kwon, Dae-Won Park, Si-Youn Song, Seok-Keun Yoon, and Suk-Hwan Baek

Interleukin-1 Induces MUC2 and MUC5AC Synthesis through Cyclooxygenase-2 in NCI-H292 Cells
Mol Pharmacol 2002 62: 1112-1118. [Abstract] [Full Text] [PDF]  

Rana A. Al-Hallaq, Bryan R. Jarabek, Zhanyan Fu, Stefano Vicini, Barry B. Wolfe, and Robert P. Yasuda

Association of NR3A with the N-Methyl-D-aspartate Receptor NR1 and NR2 Subunits
Mol Pharmacol 2002 62: 1119-1127. [Abstract] [Full Text] [PDF]  

A. Bahn, M. Knabe, Y. Hagos, M. Rödiger, S. Godehardt, D. S. Graber-Neufeld, K. K. Evans, G. Burckhardt, and S. H. Wright

Interaction of the Metal Chelator 2,3-Dimercapto-1-propanesulfonate with the Rabbit Multispecific Organic Anion Transporter 1 (rbOAT1)
Mol Pharmacol 2002 62: 1128-1136. [Abstract] [Full Text] [PDF]  

Gunnar Schulte and Bertil B. Fredholm

Signaling Pathway from the Human Adenosine A₃ Receptor Expressed in Chinese Hamster Ovary Cells to the Extracellular Signal-Regulated Kinase 1/2
Mol Pharmacol 2002 62: 1137-1146. [Abstract] [Full Text] [PDF]  

Stephen J. Wort, Mandy Woods, Timothy D. Warner, Timothy W. Evans, and Jane A. Mitchell

Cyclooxygenase-2 Acts as an Endogenous Brake on Endothelin-1 Release by Human Pulmonary Artery Smooth Muscle Cells: Implications for Pulmonary Hypertension
Mol Pharmacol 2002 62: 1147-1153. [Abstract] [Full Text] [PDF]  

Xinjian Lin, Tsuyoshi Okuda, Alison Holzer, and Stephen B. Howell

The Copper Transporter CTR1 Regulates Cisplatin Uptake in Saccharomyces cerevisiae
Mol Pharmacol 2002 62: 1154-1159. [Abstract] [Full Text] [PDF]  

Danny Burg, Peter Wielinga, Noam Zelcer, Tohru Saeki, Gerard J. Mulder, and Piet Borst

Inhibition of the Multidrug Resistance Protein 1 (MRP1) by Peptidomimetic Glutathione-Conjugate Analogs
Mol Pharmacol 2002 62: 1160-1166. [Abstract] [Full Text] [PDF]  

R. Yaar, L. M. Cataldo, A. Tzatsos, C. E. Francis, Z. Zhao, and K. Ravid

Regulation of the A3 Adenosine Receptor Gene in Vascular Smooth Muscle Cells: Role of a cAMP and GATA Element
Mol Pharmacol 2002 62: 1167-1176. [Abstract] [Full Text] [PDF]  

Thomas A. Kocarek and Nancy A. Mercer-Haines

Squalestatin 1-Inducible Expression of Rat CYP2B: Evidence That an Endogenous Isoprenoid Is an Activator of the Constitutive Androstane Receptor
Mol Pharmacol 2002 62: 1177-1186. [Abstract] [Full Text] [PDF]  

Mu-Lan He, Taka-aki Koshimizu, Melanija Tomi, and Stanko S. Stojilkovic

Purinergic P2X₂ Receptor Desensitization Depends on Coupling between Ectodomain and C-Terminal Domain
Mol Pharmacol 2002 62: 1187-1197. [Abstract] [Full Text] [PDF]  

Maida M. de las Alas, Gerrit Los, Xinjian Lin, Buran Kurdi-Haidar, Gerald Manorek, and Stephen B. Howell

Identification of Transdominant-Negative Genetic Suppressor Elements Derived from hMSH2 That Mediate Resistance to 6-Thioguanine
Mol Pharmacol 2002 62: 1198-1206. [Abstract] [Full Text] [PDF]  

Marilee Wick, Greg Hurteau, Christina Dessev, Daniel Chan, Mark W. Geraci, Robert A. Winn, Lynn E. Heasley, and Raphael A. Nemenoff

Peroxisome Proliferator-Activated Receptor- Is a Target of Nonsteroidal Anti-Inflammatory Drugs Mediating Cyclooxygenase-Independent Inhibition of Lung Cancer Cell Growth
Mol Pharmacol 2002 62: 1207-1214. [Abstract] [Full Text] [PDF]  

Michaël Facompre, Carolina Carrasco, Pierre Colson, Claude Houssier, John D. Chisholm, David L. Van Vranken, and Christian Bailly

DNA Binding and Topoisomerase I Poisoning Activities of Novel Disaccharide Indolocarbazoles
Mol Pharmacol 2002 62: 1215-1227. [Abstract] [Full Text] [PDF]  

Ya-Chin Yang and Chung-Chin Kuo

Inhibition of Na⁺ Current by Imipramine and Related Compounds: Different Binding Kinetics as an Inactivation Stabilizer and as an Open Channel Blocker
Mol Pharmacol 2002 62: 1228-1237. [Abstract] [Full Text] [PDF]  

Donald J. Gruol, Miranda N. King, and Martin E. Kuehne

Evidence for the Locations of Distinct Steroid and Vinca Alkaloid Interaction Domains within the Murine mdr1b P-Glycoprotein
Mol Pharmacol 2002 62: 1238-1248. [Abstract] [Full Text] [PDF]  

Gary L. Waldo, James Corbitt, José L. Boyer, Gnana Ravi, Hak Sung Kim, Xiao-duo Ji, James Lacy, Kenneth A. Jacobson, and T. Kendall Harden

Quantitation of the P2Y₁ Receptor with a High Affinity Radiolabeled Antagonist
Mol Pharmacol 2002 62: 1249-1257. [Abstract] [Full Text] [PDF]  

Errata:

Correction to "The kinetics of inhibition of nicotinic acetylcholine receptors by (+)-tubocurarine and pancuronium"
Mol Pharmacol 2002 62: 1258. [Full Text] [PDF]  

Correction to "Activation of the mitogen activated protein kinase extracellular signal-regulated kinase 1 and 2 by the nitric oxide-cGMP-cGMP-dependent protein kinase axis regulates the expression of matrix metalloproteinase 13 in vascular endothelial cells"
Mol Pharmacol 2002 62: 1259. [Full Text] [PDF]  

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