Minireview:

Trudy A. Kohout and Robert J. Lefkowitz

Regulation of G Protein-Coupled Receptor Kinases and Arrestins During Receptor Desensitization
Mol Pharmacol 2003 63: 9-18. [Full Text] [PDF]  

Accelerated Communications:

Jacky Y. T. Yeung, Kevin J. Canning, Guoyun Zhu, Peter Pennefather, John F. MacDonald, and Beverley A. Orser

Tonically Activated GABA_A Receptors in Hippocampal Neurons Are High-Affinity, Low-Conductance Sensors for Extracellular GABA
Mol Pharmacol 2003 63: 2-8. [Abstract] [Full Text] [PDF]  

Articles:

Mai Marie Nielsen, Tommy Liljefors, Povl Krogsgaard-Larsen, and Jan Egebjerg

The Selective Activation of the Glutamate Receptor GluR5 by ATPA Is Controlled by Serine 741
Mol Pharmacol 2003 63: 19-25. [Abstract] [Full Text] [PDF]  

Gilles Mourier, Sébastien Dutertre, Carole Fruchart-Gaillard, André Ménez, and Denis Servent

Chemical Synthesis of MT1 and MT7 Muscarinic Toxins: Critical Role of Arg-34 in Their Interaction with M₁ Muscarinic Receptor
Mol Pharmacol 2003 63: 26-35. [Abstract] [Full Text] [PDF]  

Barbara J. Ebersole, Irache Visiers, Harel Weinstein, and Stuart C. Sealfon

Molecular Basis of Partial Agonism: Orientation of Indoleamine Ligands in the Binding Pocket of the Human Serotonin 5-HT2A Receptor Determines Relative Efficacy
Mol Pharmacol 2003 63: 36-43. [Abstract] [Full Text] [PDF]  

Chia-Ho Lin, Chia-Ching Lee, and Po-Wu Gean

Involvement of a Calcineurin Cascade in Amygdala Depotentiation and Quenching of Fear Memory
Mol Pharmacol 2003 63: 44-52. [Abstract] [Full Text] [PDF]  

Elisabetta Cagetti, Jing Liang, Igor Spigelman, and Richard W. Olsen

Withdrawal from Chronic Intermittent Ethanol Treatment Changes Subunit Composition, Reduces Synaptic Function, and Decreases Behavioral Responses to Positive Allosteric Modulators of GABA_A Receptors
Mol Pharmacol 2003 63: 53-64. [Abstract] [Full Text] [PDF]  

Xin Wang, Tatsuhiko Furukawa, Takao Nitanda, Mika Okamoto, Yoshikazu Sugimoto, Shin-Ichi Akiyama, and Masanori Baba

Breast Cancer Resistance Protein (BCRP/ABCG2) Induces Cellular Resistance to HIV-1 Nucleoside Reverse Transcriptase Inhibitors
Mol Pharmacol 2003 63: 65-72. [Abstract] [Full Text] [PDF]  

Satish C. Dogra, David Tremethick, and Brian K. May

Evidence That the Coactivator CBP/p300 Is Important for Phenobarbital-Induced but Not Basal Expression of the CYP2H1 Gene
Mol Pharmacol 2003 63: 73-80. [Abstract] [Full Text] [PDF]  

Tadeusz Pawelczyk, Marzena Podgorska, and Monika Sakowicz

The Effect of Insulin on Expression Level of Nucleoside Transporters in Diabetic Rats
Mol Pharmacol 2003 63: 81-88. [Abstract] [Full Text] [PDF]  

Andrew C. Charles, Natalya Mostovskaya, Kathleen Asas, Christopher J. Evans, Megan L. Dankovich, and Tim G. Hales

Coexpression of -Opioid Receptors with µ Receptors in GH₃ Cells Changes the Functional Response to µ Agonists from Inhibitory to Excitatory
Mol Pharmacol 2003 63: 89-95. [Abstract] [Full Text] [PDF]  

Kerri A. Schoedel, Edward M. Sellers, Roberta Palmour, and Rachel F. Tyndale

Down-Regulation of Hepatic Nicotine Metabolism and a CYP2A6-Like Enzyme in African Green Monkeys after Long-Term Nicotine Administration
Mol Pharmacol 2003 63: 96-104. [Abstract] [Full Text] [PDF]  

Jieh-Yuan Liou, Preethi Krishnan, Cheng-Chih Hsieh, Ginger E. Dutschman, and Yung-chi Cheng

Assessment of the Effect of Phosphorylated Metabolites of Anti-Human Immunodeficiency Virus and Anti-Hepatitis B Virus Pyrimidine Analogs on the Behavior of Human Deoxycytidylate Deaminase
Mol Pharmacol 2003 63: 105-110. [Abstract] [Full Text] [PDF]  

Katja Schorr, Gerhild Taimor, Heike Degenhardt, Kerstin Weber, and Klaus-Dieter Schlüter

Parathyroid Hormone-Related Peptide Is Induced by Stimulation of _1A-Adrenoceptors and Improves Resistance against Apoptosis in Coronary Endothelial Cells
Mol Pharmacol 2003 63: 111-118. [Abstract] [Full Text] [PDF]  

Diana J. Auyeung, Fay K. Kessler, and Joseph K. Ritter

Mechanism of Rat UDP-Glucuronosyltransferase 1A6 Induction by Oltipraz: Evidence for a Contribution of the Aryl Hydrocarbon Receptor Pathway
Mol Pharmacol 2003 63: 119-127. [Abstract] [Full Text] [PDF]  

Jennifer L. Berkeley and Allan I. Levey

Cell-Specific Extracellular Signal-Regulated Kinase Activation by Multiple G Protein-Coupled Receptor Families in Hippocampus
Mol Pharmacol 2003 63: 128-135. [Abstract] [Full Text] [PDF]  

Yanbin Ji and Brian M. Bennett

Activation of Microsomal Glutathione S-Transferase by Peroxynitrite
Mol Pharmacol 2003 63: 136-146. [Abstract] [Full Text] [PDF]  

Casim A. Sarkar and Douglas A. Lauffenburger

Cell-Level Pharmacokinetic Model of Granulocyte Colony-Stimulating Factor: Implications for Ligand Lifetime and Potency in Vivo
Mol Pharmacol 2003 63: 147-158. [Abstract] [Full Text] [PDF]  

Antonio Mazzocca, Sabrina Giusti, Andrew D. Hamilton, Said M. Sebti, Pietro Pantaleo, and Vinicio Carloni

Growth Inhibition by the Farnesyltransferase Inhibitor FTI-277 Involves Bcl-2 Expression and Defective Association with Raf-1 in Liver Cancer Cell Lines
Mol Pharmacol 2003 63: 159-166. [Abstract] [Full Text] [PDF]  

Qi Wu and Bruce J. Dolnick

Detection of Thymidylate Synthase Modulators by a Novel Screening Assay
Mol Pharmacol 2003 63: 167-173. [Abstract] [Full Text] [PDF]  

Wei Mun Chan, William Welch, and Rebecca Sitsapesan

Structural Characteristics That Govern Binding to, and Modulation through, the Cardiac Ryanodine Receptor Nucleotide Binding Site
Mol Pharmacol 2003 63: 174-182. [Abstract] [Full Text] [PDF]  

Paul J. Kammermeier, Margaret I. Davis, and Stephen R. Ikeda

Specificity of Metabotropic Glutamate Receptor 2 Coupling to G Proteins
Mol Pharmacol 2003 63: 183-191. [Abstract] [Full Text] [PDF]  

Lucio Tentori, Ilaria Portarena, Marcella Barbarino, Alessandra Balduzzi, Lauretta Levati, Matteo Vergati, Annamaria Biroccio, Barry Gold, Maria Luisa Lombardi, and Grazia Graziani

Inhibition of Telomerase Increases Resistance of Melanoma Cells to Temozolomide, but Not to Temozolomide Combined with Poly (ADP-Ribose) Polymerase Inhibitor
Mol Pharmacol 2003 63: 192-202. [Abstract] [Full Text] [PDF]  

Kurt Vermeire, Thomas W. Bell, Heung-Jin Choi, Qi Jin, Meinrado F. Samala, Andrej Sodoma, Erik De Clercq, and Dominique Schols

The Anti-HIV Potency of Cyclotriazadisulfonamide Analogs Is Directly Correlated with Their Ability to Down-Modulate the CD4 Receptor
Mol Pharmacol 2003 63: 203-210. [Abstract] [Full Text] [PDF]  

Donghua Yin, Yali He, Minoli A. Perera, Seoung Soo Hong, Craig Marhefka, Nina Stourman, Leonid Kirkovsky, Duane D. Miller, and James T. Dalton

Key Structural Features of Nonsteroidal Ligands for Binding and Activation of the Androgen Receptor
Mol Pharmacol 2003 63: 211-223. [Abstract] [Full Text] [PDF]  

Belen Notario, Mónica Zamora, Octavi Viñas, and Teresa Mampel

All-trans-Retinoic Acid Binds to and Inhibits Adenine Nucleotide Translocase and induces Mitochondrial Permeability Transition
Mol Pharmacol 2003 63: 224-231. [Abstract] [Full Text] [PDF]  

Shujie Wang, Zhiliang Wang, and Steven Grant

Bryostatin 1 and UCN-01 Potentiate 1--D-Arabinofuranosylcytosine-Induced Apoptosis in Human Myeloid Leukemia Cells through Disparate Mechanisms
Mol Pharmacol 2003 63: 232-242. [Abstract] [Full Text] [PDF]  

Annette Nicke, Jürgen Rettinger, and Günther Schmalzing

Monomeric and Dimeric Byproducts are the Principal Functional Elements of Higher Order P2X₁ Concatamers
Mol Pharmacol 2003 63: 243-252. [Abstract] [Full Text] [PDF]  

Virginie Lattard, Christiane Longin-Sauvageon, and Etienne Benoit

Cloning, Sequencing and Tissue Distribution of Rat Flavin-Containing Monooxygenase 4: Two Different Forms Are Produced by Tissue-Specific Alternative Splicing
Mol Pharmacol 2003 63: 253-261. [Abstract] [Full Text] [PDF]  

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