Minireview:

Hongbing Wang and Daniel R. Storm

Calmodulin-Regulated Adenylyl Cyclases: Cross-Talk and Plasticity in the Central Nervous System
Mol Pharmacol 2003 63: 463-468. [Abstract] [Full Text] [PDF]  

Perspectives:

Michael D. Randall

A New Endothelial Target for Cannabinoids
Mol Pharmacol 2003 63: 469-470. [Full Text] [PDF]  

Accelerated Communications:

Carol E. Jones, Suzanne Holden, Laurent Tenaillon, Umesh Bhatia, Klaus Seuwen, Pamela Tranter, Jonathan Turner, Rachel Kettle, Rochdi Bouhelal, Steven Charlton, N. R. Nirmala, Gabor Jarai, and Peter Finan

Expression and Characterization of a 5-oxo-6E,8Z,11Z,14Z-Eicosatetraenoic Acid Receptor Highly Expressed on Human Eosinophils and Neutrophils
Mol Pharmacol 2003 63: 471-477. [Abstract] [Full Text] [PDF]  

Articles:

Ken Arai, Yoshiko Maruyama, Motohiro Nishida, Shihori Tanabe, Shuichi Takagahara, Tohru Kozasa, Yasuo Mori, Taku Nagao, and Hitoshi Kurose

Differential Requirement of G₁₂, G₁₃, G_q, and G for Endothelin-1-Induced c-Jun NH₂-Terminal Kinase and Extracellular Signal-Regulated Kinase Activation
Mol Pharmacol 2003 63: 478-488. [Abstract] [Full Text] [PDF]  

Dallas Bednarczyk, Sean Ekins, James H. Wikel, and Stephen H. Wright

Influence of Molecular Structure on Substrate Binding to the Human Organic Cation Transporter, hOCT1
Mol Pharmacol 2003 63: 489-498. [Abstract] [Full Text] [PDF]  

Gregory M. Lipkind and Harry A. Fozzard

Molecular Modeling of Interactions of Dihydropyridines and Phenylalkylamines with the Inner Pore of the L-Type Ca²⁺ Channel
Mol Pharmacol 2003 63: 499-511. [Abstract] [Full Text] [PDF]  

Yang Hee Cho, Chang Ho Lee, and Sang Geon Kim

Potentiation of Lipopolysaccharide-Inducible Cyclooxygenase 2 Expression by C2-Ceramide via c-Jun N-Terminal Kinase-Mediated Activation of CCAAT/Enhancer Binding Protein in Macrophages
Mol Pharmacol 2003 63: 512-523. [Abstract] [Full Text] [PDF]  

Katsuyoshi Kawana, Togo Ikuta, Yasuhito Kobayashi, Osamu Gotoh, Ken Takeda, and Kaname Kawajiri

Molecular Mechanism of Nuclear Translocation of an Orphan Nuclear Receptor, SXR
Mol Pharmacol 2003 63: 524-531. [Abstract] [Full Text] [PDF]  

Sumio Ohtsuki, Takuya Takizawa, Hitomi Takanaga, Nobuyuki Terasaki, Takeo Kitazawa, Masako Sasaki, Takaaki Abe, Ken-ichi Hosoya, and Tetsuya Terasaki

In Vitro Study of the Functional Expression of Organic Anion Transporting Polypeptide 3 at Rat Choroid Plexus Epithelial Cells and Its Involvement in the Cerebrospinal Fluid-to-Blood Transport of Estrone-3-Sulfate
Mol Pharmacol 2003 63: 532-537. [Abstract] [Full Text] [PDF]  

Sarah Gallois-Montbrun, Yuxing Chen, Hélène Dutartre, Magali Sophys, Solange Morera, Catherine Guerreiro, Benoit Schneider, Laurence Mulard, Joël Janin, Michel Veron, Dominique Deville-Bonne, and Bruno Canard

Structural Analysis of the Activation of Ribavirin Analogs by NDP Kinase: Comparison with Other Ribavirin Targets
Mol Pharmacol 2003 63: 538-546. [Abstract] [Full Text] [PDF]  

Michael Madeja, Thorsten Leicher, Patrick Friederich, Mark A. Punke, Wilhelm Haverkamp, Ulrich Mußhoff, Günter Breithardt, and Erwin-Josef Speckmann

Molecular Site of Action of the Antiarrhythmic Drug Propafenone at the Voltage-Operated Potassium Channel Kv2.1
Mol Pharmacol 2003 63: 547-556. [Abstract] [Full Text] [PDF]  

Donna Newman, Morito Sakaue, Ja Seok Koo, Kyung-Su Kim, Seung Joon Baek, Thomas Eling, and Anton M. Jetten

Differential Regulation of Nonsteroidal Anti-Inflammatory Drug-Activated Gene in Normal Human Tracheobronchial Epithelial and Lung Carcinoma Cells by Retinoids
Mol Pharmacol 2003 63: 557-564. [Abstract] [Full Text] [PDF]  

Francesca Tosetti, Roberta Venè, Giuseppe Arena, Monica Morini, Simona Minghelli, Douglas M. Noonan, and Adriana Albini

N-(4-Hydroxyphenyl)retinamide Inhibits Retinoblastoma Growth through Reactive Oxygen Species-Mediated Cell Death
Mol Pharmacol 2003 63: 565-573. [Abstract] [Full Text] [PDF]  

Ningshan Wang, Avi Orr-Urtreger, Joab Chapman, Ruth Rabinowitz, and Amos D. Korczyn

Deficiency of Nicotinic Acetylcholine Receptor 4 Subunit Causes Autonomic Cardiac and Intestinal Dysfunction
Mol Pharmacol 2003 63: 574-580. [Abstract] [Full Text] [PDF]  

Patricia Sancho, Alfonso Troyano, Carlos Fernández, Elena De Blas, and Patricio Aller

Differential Effects of Catalase on Apoptosis Induction in Human Promonocytic Cells. Relationships with Heat-Shock Protein Expression
Mol Pharmacol 2003 63: 581-589. [Abstract] [Full Text] [PDF]  

Amy G. Aslamkhan, Yong-Hae Han, Xiao-Ping Yang, Rudolfs K. Zalups, and John B. Pritchard

Human Renal Organic Anion Transporter 1-Dependent Uptake and Toxicity of Mercuric-Thiol Conjugates in Madin-Darby Canine Kidney Cells
Mol Pharmacol 2003 63: 590-596. [Abstract] [Full Text] [PDF]  

Zhijuan Song and Richard S. Pollenz

Functional Analysis of Murine Aryl Hydrocarbon (AH) Receptors Defective in Nuclear Import: Impact on AH Receptor Degradation and Gene Regulation
Mol Pharmacol 2003 63: 597-606. [Abstract] [Full Text] [PDF]  

Kyung Mi Jung, Ki Sook Park, Jae Ho Oh, Soo Youn Jung, Ki Hwa Yang, Youn Sook Song, Dong Ju Son, Young Hyun Park, Yeo Pyo Yun, Myung Koo Lee, Ki Wan Oh, and Jin Tae Hong

Activation of p38 Mitogen-Activated Protein Kinase and Activator Protein-1 during the Promotion of Neurite Extension of PC-12 Cells by 15-Deoxy-^12,14-prostaglandin J₂
Mol Pharmacol 2003 63: 607-616. [Abstract] [Full Text] [PDF]  

George P. Dinos, Sean R. Connell, Knud H. Nierhaus, and Dimitrios L. Kalpaxis

Erythromycin, Roxithromycin, and Clarithromycin: Use of Slow-Binding Kinetics to Compare Their in Vitro Interaction with a Bacterial Ribosomal Complex Active in Peptide Bond Formation
Mol Pharmacol 2003 63: 617-623. [Abstract] [Full Text] [PDF]  

Anders Haunsø, James Simpson, and Ferenc A. Antoni

Small Ligands Modulating the Activity of Mammalian Adenylyl Cyclases: A Novel Mode of Inhibition by Calmidazolium
Mol Pharmacol 2003 63: 624-631. [Abstract] [Full Text] [PDF]  

Annamaria Biroccio, Chiara Gabellini, Sarah Amodei, Barbara Benassi, Donatella Del Bufalo, Raffaella Elli, Anna Antonelli, Maurizio D'Incalci, and Gabriella Zupi

Telomere Dysfunction Increases Cisplatin and Ecteinascidin-743 Sensitivity of Melanoma Cells
Mol Pharmacol 2003 63: 632-638. [Abstract] [Full Text] [PDF]  

Julio C. Reséndiz, Shuju Feng, Guilan Ji, Ketia A. Francis, Michael C. Berndt, and Michael H. Kroll

Purinergic P2Y₁₂ Receptor Blockade Inhibits Shear-Induced Platelet Phosphatidylinositol 3-Kinase Activation
Mol Pharmacol 2003 63: 639-645. [Abstract] [Full Text] [PDF]  

Gábor Czirják and Péter Enyedi

Ruthenium Red Inhibits TASK-3 Potassium Channel by Interconnecting Glutamate 70 of the Two Subunits
Mol Pharmacol 2003 63: 646-652. [Abstract] [Full Text] [PDF]  

Xiaohong Wu and Howard H. Gu

Cocaine Affinity Decreased by Mutations of Aromatic Residue Phenylalanine 105 in the Transmembrane Domain 2 of Dopamine Transporter
Mol Pharmacol 2003 63: 653-658. [Abstract] [Full Text] [PDF]  

Jean-François Desaphy, Sabata Pierno, Annamaria De Luca, Paola Didonna, and Diana Conte Camerino

Different Ability of Clenbuterol and Salbutamol to Block Sodium Channels Predicts Their Therapeutic Use in Muscle Excitability Disorders
Mol Pharmacol 2003 63: 659-670. [Abstract] [Full Text] [PDF]  

Nuria A. Callejas, Amalia Fernández-Martínez, Antonio Castrillo, Lisardo Boscá, and Paloma Martín-Sanz

Selective Inhibitors of Cyclooxygenase-2 Delay the Activation of Nuclear Factor B and Attenuate the Expression of Inflammatory Genes in Murine Macrophages Treated with Lipopolysaccharide
Mol Pharmacol 2003 63: 671-677. [Abstract] [Full Text] [PDF]  

Kathy A. Aldern, Stephanie L. Ciesla, Kristine L. Winegarden, and Karl Y. Hostetler

Increased Antiviral Activity of 1-O-Hexadecyloxypropyl-[2-¹⁴C]cidofovir in MRC-5 Human Lung Fibroblasts Is Explained by Unique Cellular Uptake and Metabolism
Mol Pharmacol 2003 63: 678-681. [Abstract] [Full Text] [PDF]  

Hans-Jörg Habisch, Antonius C. F. Gorren, Haiying Liang, Richard C. Venema, John F. Parkinson, Kurt Schmidt, and Bernd Mayer

Pharmacological Interference with Dimerization of Human Neuronal Nitric-Oxide Synthase Expressed in Adenovirus-Infected DLD-1 Cells
Mol Pharmacol 2003 63: 682-689. [Abstract] [Full Text] [PDF]  

Young Hae Chong, Yoo Jung Shin, and Yoo-Hun Suh

Cyclic AMP Inhibition of Tumor Necrosis Factor Production Induced by Amyloidogenic C-Terminal Peptide of Alzheimer's Amyloid Precursor Protein in Macrophages: Involvement of Multiple Intracellular Pathways and Cyclic AMP Response Element Binding Protein
Mol Pharmacol 2003 63: 690-698. [Abstract] [Full Text] [PDF]  

László Offertáler, Fong-Ming Mo, Sándor Bátkai, Jie Liu, Malcolm Begg, Raj K. Razdan, Billy R. Martin, Richard D. Bukoski, and George Kunos

Selective Ligands and Cellular Effectors of a G Protein-Coupled Endothelial Cannabinoid Receptor
Mol Pharmacol 2003 63: 699-705. [Abstract] [Full Text] [PDF]  

Long T. Wen, Charles C. Caldwell, and Aileen F. Knowles

Poly(ADP-ribose) Polymerase Activation and Changes in Bax Protein Expression Associated with Extracellular ATP-Mediated Apoptosis in Human Embryonic Kidney 293-P2X₇ Cells
Mol Pharmacol 2003 63: 706-713. [Abstract] [Full Text] [PDF]  

Irene Hunter, Hannah J. Cobban, Peter Vandenabeele, David J. MacEwan, and Graeme F. Nixon

Tumor Necrosis Factor--Induced Activation of RhoA in Airway Smooth Muscle Cells: Role in the Ca²⁺ Sensitization of Myosin Light Chain₂₀ Phosphorylation
Mol Pharmacol 2003 63: 714-721. [Abstract] [Full Text] [PDF]  

Shi Gu, Sharon L. Ripp, Russell A. Prough, and Thomas E. Geoghegan

Dehydroepiandrosterone Affects the Expression of Multiple Genes in Rat Liver Including 11-Hydroxysteroid Dehydrogenase Type 1: A cDNA Array Analysis
Mol Pharmacol 2003 63: 722-731. [Abstract] [Full Text] [PDF]  

D. J. Naisbitt, M. Britschgi, G. Wong, J. Farrell, J. P. H. Depta, D. W. Chadwick, W. J. Pichler, M. Pirmohamed, and B. K. Park

Hypersensitivity Reactions to Carbamazepine: Characterization of the Specificity, Phenotype, and Cytokine Profile of Drug-Specific T Cell Clones
Mol Pharmacol 2003 63: 732-741. [Abstract] [Full Text] [PDF]  

Oscar Briz, Rocio I. R. Macias, Marta Vallejo, Augusto Silva, Maria Angeles Serrano, and Jose J. G. Marin

Usefulness of Liposomes Loaded with Cytostatic Bile Acid Derivatives to Circumvent Chemotherapy Resistance of Enterohepatic Tumors
Mol Pharmacol 2003 63: 742-750. [Abstract] [Full Text] [PDF]  

Sam R. J. Hoare, Sue K. Sullivan, Nicholas Ling, Paul D. Crowe, and Dimitri E. Grigoriadis

Mechanism of Corticotropin-Releasing Factor Type I Receptor Regulation by Nonpeptide Antagonists
Mol Pharmacol 2003 63: 751-765. [Abstract] [Full Text] [PDF] Editor's Note  

Anne Monks, Erik Harris, Curtis Hose, John Connelly, and Edward A. Sausville

Genotoxic Profiling of MCF-7 Breast Cancer Cell Line Elucidates Gene Expression Modifications Underlying Toxicity of the Anticancer Drug 2-(4-Amino-3-methylphenyl)-5-fluorobenzothiazole
Mol Pharmacol 2003 63: 766-772. [Abstract] [Full Text] [PDF]  

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