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September 2003; 64 (3)   [Index by Author]  [Cover Caption] [Supplemental Data]
       Minireview
       Perspective
       Accelerated Communications
       Articles
       Errata
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Minireview:

Donald H. Maurice, Daniel Palmer, Douglas G. Tilley, Heather A. Dunkerley, Stuart J. Netherton, Daniel R. Raymond, Hisham S. Elbatarny, and Sandra L. Jimmo
Cyclic Nucleotide Phosphodiesterase Activity, Expression, and Targeting in Cells of the Cardiovascular System
Mol Pharmacol 2003 64: 533-546. [Abstract] [Full Text] [PDF]  

Perspective:

John R. Hepler
RGS Protein and G Protein Interactions: A Little Help from Their Friends
Mol Pharmacol 2003 64: 547-549. [Full Text] [PDF]  

Accelerated Communications:

Mark A. Bittinger, Linh P. Nguyen, and Christopher A. Bradfield
Aspartate Aminotransferase Generates Proagonists of the Aryl Hydrocarbon Receptor
Mol Pharmacol 2003 64: 550-556. [Abstract] [Full Text] [PDF]  

Articles:

Jing-Qiong Kang, Zhao Zhong Chong, and Kenneth Maiese
Critical Role for Akt1 in the Modulation of Apoptotic Phosphatidylserine Exposure and Microglial Activation
Mol Pharmacol 2003 64: 557-569. [Abstract] [Full Text] [PDF]  

Helena Andersson, Aaron M. D'Antona, Debra A. Kendall, Gunnar Von Heijne, and Chen-Ni Chin
Membrane Assembly of the Cannabinoid Receptor 1: Impact of a Long N-Terminal Tail
Mol Pharmacol 2003 64: 570-577. [Abstract] [Full Text] [PDF]  

Sophie Mourlevat, Jean-Denis Troadec, Merle Ruberg, and Patrick P. Michel
Prevention of Dopaminergic Neuronal Death by Cyclic AMP in Mixed Neuronal/Glial Mesencephalic Cultures Requires the Repression of Presumptive Astrocytes
Mol Pharmacol 2003 64: 578-586. [Abstract] [Full Text] [PDF]  

Anju Anne Roy, Kara E. Lemberg, and Peter Chidiac
Recruitment of RGS2 and RGS4 to the Plasma Membrane by G Proteins and Receptors Reflects Functional Interactions
Mol Pharmacol 2003 64: 587-593. [Abstract] [Full Text] [PDF]  

Jing Bi, Xinli Hu, Horace H. Loh, and Li-Na Wei
Mouse {kappa}-Opioid Receptor mRNA Differential Transport in Neurons
Mol Pharmacol 2003 64: 594-599. [Abstract] [Full Text] [PDF]  

Christophe Marchand, Allison A. Johnson, Rajeshri G. Karki, Godwin C. G. Pais, Xuechun Zhang, Kiriana Cowansage, Tapan A. Patel, Marc C. Nicklaus, Terrence R. Burke, Jr., and Yves Pommier
Metal-Dependent Inhibition of HIV-1 Integrase by {beta}-Diketo Acids and Resistance of the Soluble Double-Mutant (F185K/C280S)
Mol Pharmacol 2003 64: 600-609. [Abstract] [Full Text] [PDF]  

Yasuo Imai, Sakiyo Asada, Satomi Tsukahara, Etsuko Ishikawa, Takashi Tsuruo, and Yoshikazu Sugimoto
Breast Cancer Resistance Protein Exports Sulfated Estrogens but Not Free Estrogens
Mol Pharmacol 2003 64: 610-618. [Abstract] [Full Text] [PDF]  

Maryka Quik, Tanuja Bordia, Michaella Okihara, Hong Fan, Michael J. Marks, J. Michael McIntosh, and Paul Whiteaker
L-DOPA Treatment Modulates Nicotinic Receptors in Monkey Striatum
Mol Pharmacol 2003 64: 619-628. [Abstract] [Full Text] [PDF]  

Susana Sarnago, Ramón Roca, Antonio De Blasi, Alfonso Valencia, Federico Mayor, Jr., and Cristina Murga
Involvement of Intramolecular Interactions in the Regulation of G Protein-Coupled Receptor Kinase 2
Mol Pharmacol 2003 64: 629-639. [Abstract] [Full Text] [PDF]  

Katrina Murphy, Volodymyr Gerzanich, Hui Zhou, Svetlana Ivanova, Yafeng Dong, Gloria Hoffman, G. Alexander West, H. Richard Winn, and J. Marc Simard
Adenosine-A2a Receptor Down-Regulates Cerebral Smooth Muscle L-Type Ca2+ Channel Activity via Protein Tyrosine Phosphatase, Not cAMP-Dependent Protein Kinase
Mol Pharmacol 2003 64: 640-649. [Abstract] [Full Text] [PDF]  

Lisa K. Lyford, Adrian D. Sproul, Donnie Eddins, James T. McLaughlin, and Robert L. Rosenberg
Agonist-Induced Conformational Changes in the Extracellular Domain of {alpha}7 Nicotinic Acetylcholine Receptors
Mol Pharmacol 2003 64: 650-658. [Abstract] [Full Text] [PDF]  

Eleni Aklillu, Juan Antonio Carrillo, Eyasu Makonnen, Karin Hellman, Marià Pitarque, Leif Bertilsson, and Magnus Ingelman-Sundberg
Genetic Polymorphism of CYP1A2 in Ethiopians Affecting Induction and Expression: Characterization of Novel Haplotypes with Single-Nucleotide Polymorphisms in Intron 1
Mol Pharmacol 2003 64: 659-669. [Abstract] [Full Text] [PDF]  

Brian B. Hasinoff, Patricia E. Schroeder, and Daywin Patel
The Metabolites of the Cardioprotective Drug Dexrazoxane Do Not Protect Myocytes from Doxorubicin-Induced Cytotoxicity
Mol Pharmacol 2003 64: 670-678. [Abstract] [Full Text] [PDF]  

Jillian G. Baker, Ian P. Hall, and Stephen J. Hill
Influence of Agonist Efficacy and Receptor Phosphorylation on Antagonist Affinity Measurements: Differences between Second Messenger and Reporter Gene Responses
Mol Pharmacol 2003 64: 679-688. [Abstract] [Full Text] [PDF]  

Yoshifumi Kawanabe, Kazuhiko Nozaki, Nobuo Hashimoto, and Tomoh Masaki
Characterization of Ca2+ Channels and G Proteins Involved in Arachidonic Acid Release by Endothelin-1/EndothelinA Receptor
Mol Pharmacol 2003 64: 689-695. [Abstract] [Full Text] [PDF]  

Delphine Chabut, Anne-Marie Fischer, Sylvia Colliec-Jouault, Ingrid Laurendeau, Sabine Matou, Bernard Le Bonniec, and Dominique Helley
Low Molecular Weight Fucoidan and Heparin Enhance the Basic Fibroblast Growth Factor-Induced Tube Formation of Endothelial Cells through Heparan Sulfate-Dependent {alpha}6 Overexpression
Mol Pharmacol 2003 64: 696-702. [Abstract] [Full Text] [PDF]  

Lu Chen, Alaa El-Husseini, Susumu Tomita, David S. Bredt, and Roger A. Nicoll
Stargazin Differentially Controls the Trafficking of {alpha}-Amino-3-hydroxyl-5-methyl-4-isoxazolepropionate and Kainate Receptors
Mol Pharmacol 2003 64: 703-706. [Abstract] [Full Text] [PDF]  

Jeanne Wendling, Aimé Marchand, Alain Mauviel, and Franck Verrecchia
5-Fluorouracil Blocks Transforming Growth Factor-{beta}–Induced {alpha}2 Type I Collagen Gene (COL1A2) Expression in Human Fibroblasts via c-Jun NH2-Terminal Kinase/Activator Protein-1 Activation
Mol Pharmacol 2003 64: 707-713. [Abstract] [Full Text] [PDF]  

Donna L. Dehn, David Siegel, Elizabeth Swann, Christopher J. Moody, and David Ross
Biochemical, Cytotoxic, and Genotoxic Effects of ES936, a Mechanism-Based Inhibitor of NAD(P)H:quinone Oxidoreductase 1, in Cellular Systems
Mol Pharmacol 2003 64: 714-720. [Abstract] [Full Text] [PDF]  

Yoe-Sik Bae, Jun Chul Park, Rong He, Richard D. Ye, Jong-Young Kwak, Pann-Ghill Suh, and Sung Ho Ryu
Differential Signaling of Formyl Peptide Receptor-Like 1 by Trp-Lys-Tyr-Met-Val-Met-CONH2 or Lipoxin A4 in Human Neutrophils
Mol Pharmacol 2003 64: 721-730. [Abstract] [Full Text] [PDF]  

Julie A. O'Brien, Wei Lemaire, Tsing-Bau Chen, Raymond S. L. Chang, Marlene A. Jacobson, Sookhee N. Ha, Craig W. Lindsley, Hervé J. Schaffhauser, Cyrille Sur, Douglas J. Pettibone, P. Jeffrey Conn, and David L. Williams, Jr.
A Family of Highly Selective Allosteric Modulators of the Metabotropic Glutamate Receptor Subtype 5
Mol Pharmacol 2003 64: 731-740. [Abstract] [Full Text] [PDF]  

Andrei Kondratiev and Gordon F. Tomaselli
Altered Gating and Local Anesthetic Block Mediated by Residues in the I-S6 and II-S6 Transmembrane Segments of Voltage-Dependent Na+ Channels
Mol Pharmacol 2003 64: 741-752. [Abstract] [Full Text] [PDF]  

Saku T. Sinkkonen, Salla Mansikkamäki, Tommi Möykkynen, Hartmut Lüddens, Mikko Uusi-Oukari, and Esa R. Korpi
Receptor Subtype-Dependent Positive and Negative Modulation of GABAA Receptor Function by Niflumic Acid, a Nonsteroidal Anti-Inflammatory Drug
Mol Pharmacol 2003 64: 753-763. [Abstract] [Full Text] [PDF]  

Àgatha Cabrero, Mireia Jové, Anna Planavila, Manuel Merlos, Juan C. Laguna, and Manuel Vázquez-Carrera
Down-Regulation of Acyl-CoA Oxidase Gene Expression in Heart of Troglitazone-Treated Mice through a Mechanism Involving Chicken Ovalbumin Upstream Promoter Transcription Factor II
Mol Pharmacol 2003 64: 764-772. [Abstract] [Full Text] [PDF]  

M. Carmen Jiménez-Sainz, Beate Fast, Federico Mayor, Jr., and Anna M. Aragay
Signaling Pathways for Monocyte Chemoattractant Protein 1-Mediated Extracellular Signal-Regulated Kinase Activation
Mol Pharmacol 2003 64: 773-782. [Abstract] [Full Text] [PDF]  

Errata:

Correction to "Prostacylin receptor activation inhibits proliferation of aortic smooth muscle cells by regulating cAMP response element-binding protein- and pocket protein-dependent cyclin A gene expression"
Mol Pharmacol 2003 64: 783. [Full Text] [PDF]  

Correction to "Enhancement of long-term potentiation by a potent nitric oxide-guanylyl cyclase activator, 3-(5-hydroxymethyl-2-furyl)-1-benzyl-indazole"
Mol Pharmacol 2003 64: 784. [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

About the cover: Model depicting potential role of Ca2+-mediated regulation of cardiomyocyte cAMP and cGMP levels. See the article by Maurice et al. on page 533 of this issue.


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