Minireview:

Jeffrey S. Forrester, Stephen B. Milne, Pavlina T. Ivanova, and H. Alex Brown

Computational Lipidomics: A Multiplexed Analysis of Dynamic Changes in Membrane Lipid Composition during Signal Transduction
Mol Pharmacol 2004 65: 813-821. [Abstract] [Full Text] [PDF]  

Perspectives:

Kanchana Natarajan, Guoyong Yin, and Bradford C. Berk

Scaffolds Direct Src-Specific Signaling in Response to Angiotensin II: New Roles for Cas and GIT1
Mol Pharmacol 2004 65: 822-825. [Full Text] [PDF]  

Accelerated Communications:

Mika Kurkela, Saila Mörsky, Jouni Hirvonen, Risto Kostiainen, and Moshe Finel

An Active and Water-Soluble Truncation Mutant of the Human UDP-Glucuronosyltransferase 1A9
Mol Pharmacol 2004 65: 826-831. [Abstract] [Full Text] [PDF]  

Articles:

Moe Kyaw, Masanori Yoshizumi, Koichiro Tsuchiya, Shoji Kagami, Yuki Izawa, Yoshiko Fujita, Nermin Ali, Yasuhisa Kanematsu, Kazunori Toida, Kazunori Ishimura, and Toshiaki Tamaki

Src and Cas Are Essentially but Differentially Involved in Angiotensin II-Stimulated Migration of Vascular Smooth Muscle Cells via Extracellular Signal-Regulated Kinase 1/2 and c-Jun NH₂-Terminal Kinase Activation
Mol Pharmacol 2004 65: 832-841. [Abstract] [Full Text] [PDF]  

Leslie J. Dickmann, Charles W. Locuson, Jeffrey P. Jones, and Allan E. Rettie

Differential Roles of Arg97, Asp293, and Arg108 in Enzyme Stability and Substrate Specificity of CYP2C9
Mol Pharmacol 2004 65: 842-850. [Abstract] [Full Text] [PDF]  

Gustavo López-López, Laura Moreno, Angel Cogolludo, Milagros Galisteo, Manuel Ibarra, Juan Duarte, Federica Lodi, Juan Tamargo, and Francisco Perez-Vizcaino

Nitric Oxide (NO) Scavenging and NO Protecting Effects of Quercetin and Their Biological Significance in Vascular Smooth Muscle
Mol Pharmacol 2004 65: 851-859. [Abstract] [Full Text] [PDF]  

Agnes Rinaldo-Matthis, Chiara Rampazzo, Jan Balzarini, Peter Reichard, Vera Bianchi, and Pär Nordlund

Crystal Structures of the Mitochondrial Deoxyribonucleotidase in Complex with Two Specific Inhibitors
Mol Pharmacol 2004 65: 860-867. [Abstract] [Full Text] [PDF]  

Darren R. March, Lavinia M. Proctor, Martin J. Stoermer, Robert Sbaglia, Giovanni Abbenante, Robert C. Reid, Trent M. Woodruff, Khemar Wadi, Natalii Paczkowski, Joel D. A. Tyndall, Stephen M. Taylor, and David P. Fairlie

Potent Cyclic Antagonists of the Complement C5a Receptor on Human Polymorphonuclear Leukocytes. Relationships between Structures and Activity
Mol Pharmacol 2004 65: 868-879. [Abstract] [Full Text] [PDF]  

Dietlind Zohlnhöfer, Thomas G. Nührenberg, Franz-Josef Neumann, Thomas Richter, Andreas E. May, Roland Schmidt, Katja Denker, Matthias A. Clauss, Albert Schömig, and Patrick A. Baeuerle

Rapamycin Effects Transcriptional Programs in Smooth Muscle Cells Controlling Proliferative and Inflammatory Properties
Mol Pharmacol 2004 65: 880-889. [Abstract] [Full Text] [PDF]  

Xinkang Wang, Giora Z. Feuerstein, Lin Xu, Hugh Wang, William A. Schumacher, Martin L. Ogletree, Rebecca Taub, James J.-W. Duan, Carl P. Decicco, and Rui-Qin Liu

Inhibition of Tumor Necrosis Factor--Converting Enzyme by a Selective Antagonist Protects Brain from Focal Ischemic Injury in Rats
Mol Pharmacol 2004 65: 890-896. [Abstract] [Full Text] [PDF]  

Philippe Depeille, Pierre Cuq, Sophie Mary, Isabelle Passagne, Alexandre Evrard, Didier Cupissol, and Laurence Vian

Glutathione S-Transferase M1 and Multidrug Resistance Protein 1 Act in Synergy to Protect Melanoma Cells from Vincristine Effects
Mol Pharmacol 2004 65: 897-905. [Abstract] [Full Text] [PDF]  

G. Kevin Chen, Sanja Sale, Thomas Tan, Ralph P. Ermoian, and Branimir I. Sikic

CCAAT/Enhancer-Binding Protein (Nuclear Factor for Interleukin 6) Transactivates the Human MDR1 Gene by Interaction with an Inverted CCAAT Box in Human Cancer Cells
Mol Pharmacol 2004 65: 906-916. [Abstract] [Full Text] [PDF]  

Rima Mouawad, Yuan Li, and Madhu B. Anand-Srivastava

Atrial Natriuretic Peptide-C Receptor-Induced Attenuation of Adenylyl Cyclase Signaling Activates Phosphatidylinositol Turnover in A10 Vascular Smooth Muscle Cells
Mol Pharmacol 2004 65: 917-924. [Abstract] [Full Text] [PDF]  

Thack T. Lang, James D. Young, and Carol E. Cass

Interactions of Nucleoside Analogs, Caffeine, and Nicotine with Human Concentrative Nucleoside Transporters 1 and 2 Stably Produced in a Transport-Defective Human Cell Line
Mol Pharmacol 2004 65: 925-933. [Abstract] [Full Text] [PDF]  

Lise Andrieux, Sophie Langouët, Alain Fautrel, Fréderic Ezan, Joel A. Krauser, Jean F. Savouret, F. Peter Guengerich, Georges Baffet, and André Guillouzo

Aryl Hydrocarbon Receptor Activation and Cytochrome P450 1A Induction by the Mitogen-Activated Protein Kinase Inhibitor U0126 in Hepatocytes
Mol Pharmacol 2004 65: 934-943. [Abstract] [Full Text] [PDF]  

J. Michael McIntosh, Layla Azam, Sarah Staheli, Cheryl Dowell, Jon M. Lindstrom, Alexander Kuryatov, James E. Garrett, Michael J. Marks, and Paul Whiteaker

Analogs of -Conotoxin MII Are Selective for 6-Containing Nicotinic Acetylcholine Receptors
Mol Pharmacol 2004 65: 944-952. [Abstract] [Full Text] [PDF]  

Philip A. Gregory, Rikke H. Lewinsky, Dione A. Gardner-Stephen, and Peter I. Mackenzie

Coordinate Regulation of the Human UDP-Glucuronosyltransferase 1A8, 1A9, and 1A10 Genes by Hepatocyte Nuclear Factor 1 and the Caudal-Related Homeodomain Protein 2
Mol Pharmacol 2004 65: 953-963. [Abstract] [Full Text] [PDF]  

Ilaria Tommasini and Orazio Cantoni

Dexamethasone Promotes Toxicity in U937 Cells Exposed to Otherwise Nontoxic Concentrations of Peroxynitrite: Pivotal Role for Lipocortin 1-Mediated Inhibition of Cytosolic Phospholipase A₂
Mol Pharmacol 2004 65: 964-972. [Abstract] [Full Text] [PDF]  

Teruhisa Nomura, Run Lu, Michael L. Pucci, and Victor L. Schuster

The Two-Step Model of Prostaglandin Signal Termination: In Vitro Reconstitution with the Prostaglandin Transporter and Prostaglandin 15 Dehydrogenase
Mol Pharmacol 2004 65: 973-978. [Abstract] [Full Text] [PDF]  

Clare A. Jones, Catherine Vial, Lynda A. Sellers, Pat P. A. Humphrey, Richard J. Evans, and Iain P. Chessell

Functional Regulation of P2X₆ Receptors by N-Linked Glycosylation: Identification of a Novel -Methylene ATP-Sensitive Phenotype
Mol Pharmacol 2004 65: 979-985. [Abstract] [Full Text] [PDF]  

Jillian G. Baker, Ian P. Hall, and Stephen J. Hill

Temporal Characteristics of cAMP Response Element-Mediated Gene Transcription: Requirement for Sustained cAMP Production
Mol Pharmacol 2004 65: 986-998. [Abstract] [Full Text] [PDF]  

Erica J. Carrier, Christopher S. Kearn, Andrew J. Barkmeier, Nicole M. Breese, Wenqi Yang, Kasem Nithipatikom, Sandra L. Pfister, William B. Campbell, and Cecilia J. Hillard

Cultured Rat Microglial Cells Synthesize the Endocannabinoid 2-Arachidonylglycerol, Which Increases Proliferation via a CB₂ Receptor-Dependent Mechanism
Mol Pharmacol 2004 65: 999-1007. [Abstract] [Full Text] [PDF]  

Keiko Shimamoto, Ryuichi Sakai, Kiyo Takaoka, Noboru Yumoto, Terumi Nakajima, Susan G. Amara, and Yasushi Shigeri

Characterization of Novel L-threo--Benzyloxyaspartate Derivatives, Potent Blockers of the Glutamate Transporters
Mol Pharmacol 2004 65: 1008-1015. [Abstract] [Full Text] [PDF]  

Joseph A. Caruso, Patricia A. Mathieu, Aby Joiakim, Brendan Leeson, David Kessel, Bonnie F. Sloane, and John J. Reiners, Jr.

Differential Susceptibilities of Murine Hepatoma 1c1c7 and Tao Cells to the Lysosomal Photosensitizer NPe6: Influence of Aryl Hydrocarbon Receptor on Lysosomal Fragility and Protease Contents
Mol Pharmacol 2004 65: 1016-1028. [Abstract] [Full Text] [PDF]  

A. Marchand, R. Barouki, and M. Garlatti

Regulation of NAD(P)H:Quinone Oxidoreductase 1 Gene Expression by CYP1A1 Activity
Mol Pharmacol 2004 65: 1029-1037. [Abstract] [Full Text] [PDF]  

Jennifer D. Bilyeu, Ganesh R. Panta, Lakita G. Cavin, Christina M. Barrett, Eddie J. Turner, Trevor W. Sweatman, Mervyn Israel, Leonard Lothstein, and Marcello Arsura

Circumvention of Nuclear Factor B-Induced Chemoresistance by Cytoplasmic-Targeted Anthracyclines
Mol Pharmacol 2004 65: 1038-1047. [Abstract] [Full Text] [PDF]  

Errata:

Correction to "8R-Lisuride is a potent stereospecific histamine H1-receptor partial agonist"
Mol Pharmacol 2004 65: 1048. [Full Text] [PDF]  

Correction to "Up-regulation of brain nicotinic acetylcholine receptors in the rat during long-term self-administration of nicotine: disproportionate increase of the 6 subunit"
Mol Pharmacol 2004 65: 1049. [Full Text] [PDF]  

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