Minireview:

Dezhong Yin, Shai Gavi, Hsien-yu Wang, and Craig C. Malbon

Probing Receptor Structure/Function with Chimeric G-Protein-Coupled Receptors
Mol Pharmacol 2004 65: 1323-1332. [Abstract] [Full Text] [PDF]  

Perspectives:

Charles W. Luetje

Getting Past the Asterisk: the Subunit Composition of Presynaptic Nicotinic Receptors That Modulate Striatal Dopamine Release
Mol Pharmacol 2004 65: 1333-1335. [Full Text] [PDF]  

Articles:

Randy M. Wadkins, Janice L Hyatt, Kyoung Jin P. Yoon, Christopher L. Morton, Richard E. Lee, Komath Damodaran, Paul Beroza, Mary K. Danks, and Philip M. Potter

Discovery of Novel Selective Inhibitors of Human Intestinal Carboxylesterase for the Amelioration of Irinotecan-Induced Diarrhea: Synthesis, Quantitative Structure-Activity Relationship Analysis, and Biological Activity
Mol Pharmacol 2004 65: 1336-1343. [Abstract] [Full Text] [PDF]  

Shinichi Ogino, Kazuhiro Tsuruma, Takashi Uehara, and Yasuyuki Nomura

Herbimycin A Abrogates Nuclear Factor-B Activation by Interacting Preferentially with the IB Kinase Subunit
Mol Pharmacol 2004 65: 1344-1351. [Abstract] [Full Text] [PDF]  

Dervla O'Malley and Jenni Harvey

Insulin Activates Native and Recombinant Large Conductance Ca²⁺-Activated Potassium Channels via a Mitogen-Activated Protein Kinase-Dependent Process
Mol Pharmacol 2004 65: 1352-1363. [Abstract] [Full Text] [PDF]  

Julia Vennekamp, Heike Wulff, Christine Beeton, Peter A. Calabresi, Stephan Grissmer, Wolfram Hänsel, and K. George Chandy

Kv1.3-Blocking 5-Phenylalkoxypsoralens: A New Class of Immunomodulators
Mol Pharmacol 2004 65: 1364-1374. [Abstract] [Full Text] [PDF]  

Anass Haimeur, Gwenaëlle Conseil, Roger G. Deeley, and Susan P.C. Cole

Mutations of Charged Amino Acids in or near the Transmembrane Helices of the Second Membrane Spanning Domain Differentially Affect the Substrate Specificity and Transport Activity of the Multidrug Resistance Protein MRP1 (ABCC1)
Mol Pharmacol 2004 65: 1375-1385. [Abstract] [Full Text] [PDF]  

Anna Kloda, John D. Clements, Richard J. Lewis, and David J. Adams

Adenosine Triphosphate Acts as Both a Competitive Antagonist and a Positive Allosteric Modulator at Recombinant N-Methyl-D-aspartate Receptors
Mol Pharmacol 2004 65: 1386-1396. [Abstract] [Full Text] [PDF]  

Jonathan P. Jackson, Stephen S. Ferguson, Rick Moore, Masahiko Negishi, and Joyce A. Goldstein

The Constitutive Active/Androstane Receptor Regulates Phenytoin Induction of Cyp2c29
Mol Pharmacol 2004 65: 1397-1404. [Abstract] [Full Text] [PDF]  

Kyle Christian, Matti Lang, Patrick Maurel, and Françoise Raffalli-Mathieu

Interaction of Heterogeneous Nuclear Ribonucleoprotein A1 with Cytochrome P450 2A6 mRNA: Implications for Post-Transcriptional Regulation of the CYP2A6 Gene
Mol Pharmacol 2004 65: 1405-1414. [Abstract] [Full Text] [PDF]  

Tomohiko Ai, Silvia G. Bompadre, Xiaohui Wang, Shenghui Hu, Min Li, and Tzyh-Chang Hwang

Capsaicin Potentiates Wild-Type and Mutant Cystic Fibrosis Transmembrane Conductance Regulator Chloride-Channel Currents
Mol Pharmacol 2004 65: 1415-1426. [Abstract] [Full Text] [PDF]  

Rico K. H. Lo and Yung H. Wong

Signal Transducer and Activator of Transcription 3 Activation by the -Opioid Receptor via G₁₄ Involves Multiple Intermediates
Mol Pharmacol 2004 65: 1427-1439. [Abstract] [Full Text] [PDF]  

Stephan Klöss, Rashi Srivastava, and Alexander Mülsch

Down-Regulation of Soluble Guanylyl Cyclase Expression by Cyclic AMP Is Mediated by mRNA-Stabilizing Protein HuR
Mol Pharmacol 2004 65: 1440-1451. [Abstract] [Full Text] [PDF]  

Nir Melamed and Baruch I. Kanner

Transmembrane Domains I and II of the -Aminobutyric Acid Transporter GAT-4 Contain Molecular Determinants of Substrate Specificity
Mol Pharmacol 2004 65: 1452-1461. [Abstract] [Full Text] [PDF]  

Chong-Bin Zhu, William A. Hewlett, Igor Feoktistov, Italo Biaggioni, and Randy D. Blakely

Adenosine Receptor, Protein Kinase G, and p38 Mitogen-Activated Protein Kinase-Dependent Up-Regulation of Serotonin Transporters Involves Both Transporter Trafficking and Activation
Mol Pharmacol 2004 65: 1462-1474. [Abstract] [Full Text] [PDF]  

I-Na Park, Il Je Cho, and Sang Geon Kim

Ceramide Negatively Regulates Glutathione S-transferase Gene Transactivation via Repression of Hepatic Nuclear Factor-1 That Is Degraded by the Ubiquitin Proteasome System
Mol Pharmacol 2004 65: 1475-1484. [Abstract] [Full Text] [PDF]  

Csilla Özvegy-Laczka, Tamás Hegeds, György Várady, Olga Ujhelly, John D. Schuetz, András Váradi, György Kéri, László Orfi, Katalin Német, and Balázs Sarkadi

High-Affinity Interaction of Tyrosine Kinase Inhibitors with the ABCG2 Multidrug Transporter
Mol Pharmacol 2004 65: 1485-1495. [Abstract] [Full Text] [PDF]  

Vladimir Beljanski, Luigi G. Marzilli, and Paul W. Doetsch

DNA Damage-Processing Pathways Involved in the Eukaryotic Cellular Response to Anticancer DNA Cross-Linking Drugs
Mol Pharmacol 2004 65: 1496-1506. [Abstract] [Full Text] [PDF]  

Stuart J. Mundell, Giordano Pula, Julia C. A. More, David E. Jane, Peter J. Roberts, and Eamonn Kelly

Activation of Cyclic AMP-Dependent Protein Kinase Inhibits the Desensitization and Internalization of Metabotropic Glutamate Receptors 1a and 1b
Mol Pharmacol 2004 65: 1507-1516. [Abstract] [Full Text] [PDF]  

Virginie Lattard, Jun Zhang, and John R. Cashman

Alternative Processing Events in Human FMO Genes
Mol Pharmacol 2004 65: 1517-1525. [Abstract] [Full Text] [PDF]  

Outi Salminen, Karen L. Murphy, J. Michael McIntosh, John Drago, Michael J. Marks, Allan C. Collins, and Sharon R. Grady

Subunit Composition and Pharmacology of Two Classes of Striatal Presynaptic Nicotinic Acetylcholine Receptors Mediating Dopamine Release in Mice
Mol Pharmacol 2004 65: 1526-1535. [Abstract] [Full Text] [PDF]  

Xiao-Qin Ren, Tatsuhiko Furukawa, Misako Haraguchi, Tomoyuki Sumizawa, Shunji Aoki, Motomasa Kobayashi, and Shin-ichi Akiyama

Function of the ABC Signature Sequences in the Human Multidrug Resistance Protein 1
Mol Pharmacol 2004 65: 1536-1542. [Abstract] [Full Text] [PDF]  

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