Perspectives:

Ana M. Rossi and Colin W. Taylor

Ca²⁺ Regulation of Inositol 1,4,5-trisphosphate Receptors: Can Ca²⁺ Function without Calmodulin?
Mol Pharmacol 2004 66: 199-203. [Abstract] [Full Text] [PDF] Correction  

Articles:

Kunlin Jin, Lin Xie, Sun Hee Kim, Sophie Parmentier-Batteur, Yunjuan Sun, Xiao Ou Mao, Jocelyn Childs, and David A. Greenberg

Defective Adult Neurogenesis in CB1 Cannabinoid Receptor Knockout Mice
Mol Pharmacol 2004 66: 204-208. [Abstract] [Full Text] [PDF]  

Trisha L. Kalbaugh, Hendrika M. A. VanDongen, and Antonius M. J. VanDongen

Ligand-Binding Residues Integrate Affinity and Efficacy in the NMDA Receptor
Mol Pharmacol 2004 66: 209-219. [Abstract] [Full Text] [PDF]  

Nimesh S. A. Patel, Salvatore Cuzzocrea, Prabal K. Chatterjee, Rosanna Di Paola, Lidia Sautebin, Domenico Britti, and Christoph Thiemermann

Reduction of Renal Ischemia-Reperfusion Injury in 5-Lipoxygenase Knockout Mice and by the 5-Lipoxygenase Inhibitor Zileuton
Mol Pharmacol 2004 66: 220-227. [Abstract] [Full Text] [PDF]  

Douglas Ramsay, I. Craig Carr, John Pediani, Juan F. Lopez-Gimenez, Richard Thurlow, Mark Fidock, and Graeme Milligan

High-Affinity Interactions between Human _1A-Adrenoceptor C-Terminal Splice Variants Produce Homo- and Heterodimers but Do Not Generate the _1L-Adrenoceptor
Mol Pharmacol 2004 66: 228-239. [Abstract] [Full Text] [PDF]  

Matthew Perry, Marcel J. de Groot, Ray Helliwell, Derek Leishman, Martin Tristani-Firouzi, Michael C. Sanguinetti, and John Mitcheson

Structural Determinants of HERG Channel Block by Clofilium and Ibutilide
Mol Pharmacol 2004 66: 240-249. [Abstract] [Full Text] [PDF]  

Arne Heydorn, Richard J. Ward, Rasmus Jorgensen, Mette M. Rosenkilde, Thomas M. Frimurer, Graeme Milligan, and Evi Kostenis

Identification of a Novel Site within G Protein Subunits Important for Specificity of Receptor-G Protein Interaction
Mol Pharmacol 2004 66: 250-259. [Abstract] [Full Text] [PDF]  

Dinesh Gautam, Thomas S. Heard, Yinghong Cui, Georgina Miller, Lanh Bloodworth, and Jürgen Wess

Cholinergic Stimulation of Salivary Secretion Studied with M₁ and M₃ Muscarinic Receptor Single- and Double-Knockout Mice
Mol Pharmacol 2004 66: 260-267. [Abstract] [Full Text] [PDF]  

Dong Xu, Hyunmin Kang, Michael Fisher, and R. L. Juliano

Strategies for Inhibition of MDR1 Gene Expression
Mol Pharmacol 2004 66: 268-275. [Abstract] [Full Text] [PDF]  

Nael Nadif Kasri, Geert Bultynck, Jeremy Smyth, Karolina Szlufcik, Jan B. Parys, Geert Callewaert, Ludwig Missiaen, Rafael A. Fissore, Katsuhiko Mikoshiba, and Humbert de Smedt

The N-terminal Ca²⁺-Independent Calmodulin-Binding Site on the Inositol 1,4,5-trisphosphate Receptor Is Responsible for Calmodulin Inhibition, Even Though This Inhibition Requires Ca²⁺
Mol Pharmacol 2004 66: 276-284. [Abstract] [Full Text] [PDF]  

Tracy E. Kim, Shin-Young Park, Chih-Hung Hsu, Ginger E. Dutschman, and Yung-Chi Cheng

Synergistic Antitumor Activity of Troxacitabine and Camptothecin in Selected Human Cancer Cell Lines
Mol Pharmacol 2004 66: 285-292. [Abstract] [Full Text] [PDF]  

Chantal Burelout, Nathalie Thibault, Sylvain Levasseur, Sébastien Simard, Paul H. Naccache, and Sylvain G. Bourgoin

Prostaglandin E₂ Inhibits the Phospholipase D Pathway Stimulated by Formyl-methionyl-leucyl-phenylalanine in Human Neutrophils. Involvement of EP₂ Receptors and Phosphatidylinositol 3-kinase
Mol Pharmacol 2004 66: 293-301. [Abstract] [Full Text] [PDF]  

Hong Huang, Jane L. Rose, and Dale G. Hoyt

p38 Mitogen-Activated Protein Kinase Mediates Synergistic Induction of Inducible Nitric-Oxide Synthase by Lipopolysaccharide and Interferon- through Signal Transducer and Activator of Transcription 1 Ser727 Phosphorylation in Murine Aortic Endothelial Cells
Mol Pharmacol 2004 66: 302-311. [Abstract] [Full Text] [PDF]  

Mohammed A. Ayoub, Angélique Levoye, Philippe Delagrange, and Ralf Jockers

Preferential Formation of MT₁/MT₂ Melatonin Receptor Heterodimers with Distinct Ligand Interaction Properties Compared with MT₂ Homodimers
Mol Pharmacol 2004 66: 312-321. [Abstract] [Full Text] [PDF] Correction  

Omar Tliba, Reynold A. Panettieri, Jr., Samira Tliba, Timothy F. Walseth, and Yassine Amrani

Tumor Necrosis Factor- Differentially Regulates the Expression of Proinflammatory Genes in Human Airway Smooth Muscle Cells by Activation of Interferon-–Dependent CD38 Pathway
Mol Pharmacol 2004 66: 322-329. [Abstract] [Full Text] [PDF]  

Koji Sasaki, Naomasa Makita, Akihiko Sunami, Harumizu Sakurada, Nobumasa Shirai, Hisataka Yokoi, Akinori Kimura, Noritsugu Tohse, Masayasu Hiraoka, and Akira Kitabatake

Unexpected Mexiletine Responses of a Mutant Cardiac Na⁺ Channel Implicate the Selectivity Filter as a Structural Determinant of Antiarrhythmic Drug Access
Mol Pharmacol 2004 66: 330-336. [Abstract] [Full Text] [PDF]  

Thomas Gray, Paul Nettesheim, Charles Loftin, Ja-Seok Koo, James Bonner, Shyamal Peddada, and Robert Langenbach

Interleukin-1–Induced Mucin Production in Human Airway Epithelium Is Mediated by Cyclooxygenase-2, Prostaglandin E₂ Receptors, and Cyclic AMP-Protein Kinase A Signaling
Mol Pharmacol 2004 66: 337-346. [Abstract] [Full Text] [PDF]  

Galya Abdrakhmanova, Lars Cleemann, Jon Lindstrom, and Martin Morad

Differential Modulation of 2 and 4 Subunits of Human Neuronal Nicotinic Acetylcholine Receptors by Acidification
Mol Pharmacol 2004 66: 347-355. [Abstract] [Full Text] [PDF] Data Supplement  

Renata Del Carmine, Paola Molinari, Maria Sbraccia, Caterina Ambrosio, and Tommaso Costa

"Induced-Fit" Mechanism for Catecholamine Binding to the ₂-Adrenergic Receptor
Mol Pharmacol 2004 66: 356-363. [Abstract] [Full Text] [PDF]  

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