Editor's Note:

Paul A. Insel

Mol Pharmacol 2005 67: 1. [Full Text] [PDF]  

Minireview:

Susan F. Steinberg

The Cardiovascular Actions of Protease-Activated Receptors
Mol Pharmacol 2005 67: 2-11. Published online September 15, 2004; 10.1124/mol.104.003103 [Abstract] [Full Text] [PDF]  

Perspectives:

Brian M. Cox

Agonists at µ-Opioid Receptors Spin the Wheels to Keep the Action Going
Mol Pharmacol 2005 67: 12-14. Published online October 20, 2004; 10.1124/mol.104.008433 [Abstract] [Full Text] [PDF] Related Article  

Accelerated Communications:

Jesse Lo Verme, Jin Fu, Giuseppe Astarita, Giovanna La Rana, Roberto Russo, Antonio Calignano, and Daniele Piomelli

The Nuclear Receptor Peroxisome Proliferator-Activated Receptor- Mediates the Anti-Inflammatory Actions of Palmitoylethanolamide
Mol Pharmacol 2005 67: 15-19. Published online October 1, 2004; 10.1124/mol.104.006353 [Abstract] [Full Text] [PDF]  

Articles:

Alex C. Conner, Debbie L. Hay, John Simms, Stephen G. Howitt, Marcus Schindler, David M. Smith, Mark Wheatley, and David R. Poyner

A Key Role for Transmembrane Prolines in Calcitonin Receptor-Like Receptor Agonist Binding and Signalling: Implications for Family B G-Protein-Coupled Receptors
Mol Pharmacol 2005 67: 20-31. [Abstract] [Full Text] [PDF]  

Maryka Quik, Silvia Vailati, Tanuja Bordia, Jennifer M. Kulak, Hong Fan, J. Michael McIntosh, Francesco Clementi, and Cecilia Gotti

Subunit Composition of Nicotinic Receptors in Monkey Striatum: Effect of Treatments with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine or L-DOPA
Mol Pharmacol 2005 67: 32-41. Published online October 6, 2004; 10.1124/mol.104.006015 [Abstract] [Full Text] [PDF]  

Xianlong Gao and Tarun B. Patel

Histidine Residues 912 and 913 in Protein Associated with Myc Are Necessary for the Inhibition of Adenylyl Cyclase Activity
Mol Pharmacol 2005 67: 42-49. Published online October 6, 2004; 10.1124/mol.104.005355 [Abstract] [Full Text] [PDF]  

Maris Lapinsh, Santa Veiksina, Staffan Uhlén, Ramona Petrovska, Ilze Mutule, Felikss Mutulis, Sviatlana Yahorava, Peteris Prusis, and Jarl E. S. Wikberg

Proteochemometric Mapping of the Interaction of Organic Compounds with Melanocortin Receptor Subtypes
Mol Pharmacol 2005 67: 50-59. Published online October 6, 2004; 10.1124/mol.104.002857 [Abstract] [Full Text] [PDF]  

David R. Bauman, Stephen I. Rudnick, Lawrence M. Szewczuk, Yi Jin, Sridhar Gopishetty, and Trevor M. Penning

Development of Nonsteroidal Anti-Inflammatory Drug Analogs and Steroid Carboxylates Selective for Human Aldo-Keto Reductase Isoforms: Potential Antineoplastic Agents That Work Independently of Cyclooxygenase Isozymes
Mol Pharmacol 2005 67: 60-68. Published online October 8, 2004; 10.1124/mol.104.006569 [Abstract] [Full Text] [PDF]  

David V. Erbe, Suyue Wang, Yan-Ling Zhang, Kimberly Harding, Leslie Kung, May Tam, Leslie Stolz, Yuzhe Xing, Sarah Furey, Ariful Qadri, Lori D. Klaman, and James F. Tobin

Ertiprotafib Improves Glycemic Control and Lowers Lipids via Multiple Mechanisms
Mol Pharmacol 2005 67: 69-77. Published online October 8, 2004; 10.1124/mol.104.005553 [Abstract] [Full Text] [PDF]  

Lisa Stalheim, Yu Ding, Anuradha Gullapalli, May M. Paing, Breann L. Wolfe, Dionne R. Morris, and JoAnn Trejo

Multiple Independent Functions of Arrestins in the Regulation of Protease-Activated Receptor-2 Signaling and Trafficking
Mol Pharmacol 2005 67: 78-87. Published online October 8, 2004; 10.1124/mol.104.006072 [Abstract] [Full Text] [PDF]  

Gengming Huang and Cornelis J. Elferink

Multiple Mechanisms Are Involved in Ah Receptor-Mediated Cell Cycle Arrest
Mol Pharmacol 2005 67: 88-96. Published online October 18, 2004; 10.1124/mol.104.002410 [Abstract] [Full Text] [PDF]  

Il Yeong Park, Eun Jung Kim, HaJeung Park, Kelly Fields, A. Keith Dunker, and ChulHee Kang

Interaction between Cardiac Calsequestrin and Drugs with Known Cardiotoxicity
Mol Pharmacol 2005 67: 97-104. Published online October 18, 2004; 10.1124/mol.104.005744 [Abstract] [Full Text] [PDF]  

Chris Stirone, Amin Boroujerdi, Sue P. Duckles, and Diana N. Krause

Estrogen Receptor Activation of Phosphoinositide-3 Kinase, Akt, and Nitric Oxide Signaling in Cerebral Blood Vessels: Rapid and Long-Term Effects
Mol Pharmacol 2005 67: 105-113. Published online October 20, 2004; 10.1124/mol.104.004465 [Abstract] [Full Text] [PDF]  

Claudia Alvarado-Castillo, T. Kendall Harden, and José L. Boyer

Regulation of P2Y₁ Receptor-Mediated Signaling by the Ectonucleoside Triphosphate Diphosphohydrolase Isozymes NTPDase1 and NTPDase2
Mol Pharmacol 2005 67: 114-122. Published online October 20, 2004; 10.1124/mol.104.006908 [Abstract] [Full Text] [PDF]  

Richard A. Pennington, Fan Gao, Steven M. Sine, and Richard J. Prince

Structural Basis for Epibatidine Selectivity at Desensitized Nicotinic Receptors
Mol Pharmacol 2005 67: 123-131. Published online October 20, 2004; 10.1124/mol.104.003665 [Abstract] [Full Text] [PDF]  

Satoshi Takida, Christopher C. Fischer, and Philip B. Wedegaertner

Palmitoylation and Plasma Membrane Targeting of RGS7 Are Promoted by _o
Mol Pharmacol 2005 67: 132-139. Published online October 20, 2004; 10.1124/mol.104.003418 [Abstract] [Full Text] [PDF]  

Stefan Seidel, Ernst A. Singer, Herwig Just, Hesso Farhan, Petra Scholze, Oliver Kudlacek, Marion Holy, Karl Koppatz, Peter Krivanek, Michael Freissmuth, and Harald H. Sitte

Amphetamines Take Two to Tango: an Oligomer-Based Counter-Transport Model of Neurotransmitter Transport Explores the Amphetamine Action
Mol Pharmacol 2005 67: 140-151. [Abstract] [Full Text] [PDF]  

Jun Chen, Ganwei Lu, and Q. Jane Wang

Protein Kinase C-Independent Effects of Protein Kinase D3 in Glucose Transport in L6 Myotubes
Mol Pharmacol 2005 67: 152-162. Published online October 20, 2004; 10.1124/mol.104.004200 [Abstract] [Full Text] [PDF]  

Jonathan Ledoux, Iain A. Greenwood, and Normand Leblanc

Dynamics of Ca²⁺-Dependent Cl^- Channel Modulation by Niflumic Acid in Rabbit Coronary Arterial Myocytes
Mol Pharmacol 2005 67: 163-173. Published online October 1, 2004; 10.1124/mol.104.004168 [Abstract] [Full Text] [PDF]  

Danhua Fan, Paula M. Bryan, Laura K. Antos, Regine J. Potthast, and Lincoln R. Potter

Down-Regulation Does Not Mediate Natriuretic Peptide-Dependent Desensitization of Natriuretic Peptide Receptor (NPR)-A or NPR-B: Guanylyl Cyclase-Linked Natriuretic Peptide Receptors Do Not Internalize
Mol Pharmacol 2005 67: 174-183. Published online September 30, 2004; 10.1124/mol.104.002436 [Abstract] [Full Text] [PDF]  

Bukhtiar H. Shah, J. Alberto Olivares-Reyes, and Kevin J. Catt

The Protein Kinase C Inhibitor Go6976 [12-(2-Cyanoethyl)-6,7,12,13-tetrahydro-13-methyl-5-oxo-5H-indolo(2,3-a)pyrrolo(3,4-c)-carbazole] Potentiates Agonist-Induced Mitogen-Activated Protein Kinase Activation through Tyrosine Phosphorylation of the Epidermal Growth Factor Receptor
Mol Pharmacol 2005 67: 184-194. Published online October 1, 2004; 10.1124/mol.104.003533 [Abstract] [Full Text] [PDF]  

Anna Torrent, David Moreno-Delgado, Jordi Gómez-Ramírez, Daniel Rodríguez-Agudo, Carlos Rodríguez-Caso, Francisca Sánchez-Jiménez, Isaac Blanco, and Jordí Ortiz

H₃ Autoreceptors Modulate Histamine Synthesis through Calcium/Calmodulin- and cAMP-Dependent Protein Kinase Pathways
Mol Pharmacol 2005 67: 195-203. Published online October 1, 2004; 10.1124/mol.104.005652 [Abstract] [Full Text] [PDF]  

Yang Gao, Elena Atanasova, Nan Sui, James D. Pancook, Jeffry D. Watkins, and Stephen Brimijoin

Gene Transfer of Cocaine Hydrolase Suppresses Cardiovascular Responses to Cocaine in Rats
Mol Pharmacol 2005 67: 204-211. Published online October 1, 2004; 10.1124/mol.104.006924 [Abstract] [Full Text] [PDF]  

Hong Lu and David J. Waxman

Antitumor Activity of Methoxymorpholinyl Doxorubicin: Potentiation by Cytochrome P450 3A Metabolism
Mol Pharmacol 2005 67: 212-219. Published online October 1, 2004; 10.1124/mol.104.005371 [Abstract] [Full Text] [PDF]  

Shun-Hsin Liang, Christopher Hassett, and Curtis J. Omiecinski

Alternative Promoters Determine Tissue-Specific Expression Profiles of the Human Microsomal Epoxide Hydrolase Gene (EPHX1)
Mol Pharmacol 2005 67: 220-230. Published online October 1, 2004; 10.1124/mol.104.005579 [Abstract] [Full Text] [PDF]  

Changlu Liu, Jingcai Chen, Chester Kuei, Steven Sutton, Diane Nepomuceno, Pascal Bonaventure, and Timothy W. Lovenberg

Relaxin-3/Insulin-Like Peptide 5 Chimeric Peptide, a Selective Ligand for G Protein-Coupled Receptor (GPCR)135 and GPCR142 over Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 7
Mol Pharmacol 2005 67: 231-240. Published online October 1, 2004; 10.1124/mol.104.006700 [Abstract] [Full Text] [PDF]  

Olivier Barbier, Hugo Girard, Yusuke Inoue, Hélène Duez, Lyne Villeneuve, Akihide Kamiya, Jean-Charles Fruchart, Chantal Guillemette, Frank J. Gonzalez, and Bart Staels

Hepatic Expression of the UGT1A9 Gene Is Governed by Hepatocyte Nuclear Factor 4
Mol Pharmacol 2005 67: 241-249. Published online October 6, 2004; 10.1124/mol.104.003863 [Abstract] [Full Text] [PDF]  

Michael A. Beazely, Jamie K. Alan, and Val J. Watts

Protein Kinase C and Epidermal Growth Factor Stimulation of Raf1 Potentiates Adenylyl Cyclase Type 6 Activation in Intact Cells
Mol Pharmacol 2005 67: 250-259. Published online October 6, 2004; 10.1124/mol.104.001370 [Abstract] [Full Text] [PDF]  

Jacqueline J. Fremont, Regina W. Wang, and Christopher D. King

Coimmunoprecipitation of UDP-Glucuronosyltransferase Isoforms and Cytochrome P450 3A4
Mol Pharmacol 2005 67: 260-262. Published online October 14, 2004; 10.1124/mol.104.006361 [Abstract] [Full Text] [PDF]  

Stuart J. Netherton and Donald H. Maurice

Vascular Endothelial Cell Cyclic Nucleotide Phosphodiesterases and Regulated Cell Migration: Implications in Angiogenesis
Mol Pharmacol 2005 67: 263-272. Published online October 8, 2004; 10.1124/mol.104.004853 [Abstract] [Full Text] [PDF]  

Vijaya L. Damaraju, Frank Visser, Jing Zhang, Delores Mowles, Amy M. L. Ng, James D. Young, Hiremagalur N. Jayaram, and Carol E. Cass

Role of Human Nucleoside Transporters in the Cellular Uptake of Two Inhibitors of IMP Dehydrogenase, Tiazofurin and Benzamide Riboside
Mol Pharmacol 2005 67: 273-279. Published online October 14, 2004; 10.1124/mol.104.004408 [Abstract] [Full Text] [PDF]  

Thomas Koch, Antje Widera, Katharina Bartzsch, Stefan Schulz, Lars-Ove Brandenburg, Nicole Wundrack, Andrea Beyer, Gisela Grecksch, and Volker Höllt

Receptor Endocytosis Counteracts the Development of Opioid Tolerance
Mol Pharmacol 2005 67: 280-287. Published online October 8, 2004; 10.1124/mol.104.004994 [Abstract] [Full Text] [PDF]  

Tracy T. Cao, Anne Brelot, and Mark von Zastrow

The Composition of the -2 Adrenergic Receptor Oligomer Affects Its Membrane Trafficking after Ligand-Induced Endocytosis
Mol Pharmacol 2005 67: 288-297. Published online October 18, 2004; 10.1124/mol.104.003608 [Abstract] [Full Text] [PDF]  

Sun Yang and Frank L. Meyskens, Jr.

Alterations in Activating Protein 1 Composition Correlate with Phenotypic Differentiation Changes Induced by Resveratrol in Human Melanoma
Mol Pharmacol 2005 67: 298-308. Published online October 18, 2004; 10.1124/mol.104.006023 [Abstract] [Full Text] [PDF]  

Dong Soo Kang, Caroline Gustafsson, Matthias Mörgelin, and L. M. Fredrik Leeb-Lundberg

B₁ Bradykinin Receptor Homo-Oligomers in Receptor Cell Surface Expression and Signaling: Effects of Receptor Fragments
Mol Pharmacol 2005 67: 309-318. Published online October 18, 2004; 10.1124/mol.104.002840 [Abstract] [Full Text] [PDF]  

Yoko Otake, Tapas K. Sengupta, Sumita Bandyopadhyay, Eleanor K. Spicer, and Daniel J. Fernandes

Retinoid-Induced Apoptosis in HL-60 Cells Is Associated with Nucleolin Down-Regulation and Destabilization of Bcl-2 mRNA
Mol Pharmacol 2005 67: 319-326. Published online October 18, 2004; 10.1124/mol.104.006080 [Abstract] [Full Text] [PDF]  

Michael T. Fisher, Mitzi Nagarkatti, and Prakash S. Nagarkatti

2,3,7,8-Tetrachlorodibenzo-p-dioxin Enhances Negative Selection of T Cells in the Thymus but Allows Autoreactive T Cells to Escape Deletion and Migrate to the Periphery
Mol Pharmacol 2005 67: 327-335. Published online October 18, 2004; 10.1124/mol.104.005868 [Abstract] [Full Text] [PDF]  

Graciela Piñeyro, Mounia Azzi, André deLéan, Peter W. Schiller, and Michel Bouvier

Reciprocal Regulation of Agonist and Inverse Agonist Signaling Efficacy upon Short-Term Treatment of the Human -Opioid Receptor with an Inverse Agonist
Mol Pharmacol 2005 67: 336-348. Published online October 20, 2004; 10.1124/mol.104.004549 [Abstract] [Full Text] [PDF]  

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