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February 2005; 67 (2)   [Index by Author]  [Cover Caption]
       Accelerated Communications
       Articles
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Accelerated Communications:

M. Foster Olive, Andrew J. Mcgeehan, Jennifer R. Kinder, Thomas McMahon, Clyde W. Hodge, Patricia H. Janak, and Robert O. Messing
The mGluR5 Antagonist 6-Methyl-2-(phenylethynyl)pyridine Decreases Ethanol Consumption via a Protein Kinase C{epsilon}-Dependent Mechanism
Mol Pharmacol 2005 67: 349-355. Published online November 17, 2004; 10.1124/mol.104.003319 [Abstract] [Full Text] [PDF]  

Articles:

Seung Joon Baek, Jong-Sik Kim, Scott M. Moore, Seong-Ho Lee, Jeanelle Martinez, and Thomas E. Eling
Cyclooxygenase Inhibitors Induce the Expression of the Tumor Suppressor Gene EGR-1, Which Results in the Up-Regulation of NAG-1, an Antitumorigenic Protein
Mol Pharmacol 2005 67: 356-364. Published online October 27, 2004; 10.1124/mol.104.005108 [Abstract] [Full Text] [PDF]  

Karin Pleban, Stephan Kopp, Edina Csaszar, Michael Peer, Thomas Hrebicek, Andreas Rizzi, Gerhard F. Ecker, and Peter Chiba
P-Glycoprotein Substrate Binding Domains Are Located at the Transmembrane Domain/Transmembrane Domain Interfaces: A Combined Photoaffinity Labeling-Protein Homology Modeling Approach
Mol Pharmacol 2005 67: 365-374. Published online October 27, 2004; 10.1124/mol.104.006973 [Abstract] [Full Text] [PDF]  

Diem T. Dinh, Hongwei Qian, Ruth Seeber, Esther Lim, Kevin Pfleger, Karin A. Eidne, and Walter G. Thomas
Helix I of {beta}-Arrestin Is Involved in Postendocytic Trafficking but Is Not Required for Membrane Translocation, Receptor Binding, and Internalization
Mol Pharmacol 2005 67: 375-382. Published online November 2, 2004; 10.1124/mol.104.004721 [Abstract] [Full Text] [PDF]  

Deborah L. Clarke, Maria G. Belvisi, Elizabeth Hardaker, Robert Newton, and Mark A. Giembycz
E-Ring 8-Isoprostanes Are Agonists at EP2- and EP4-Prostanoid Receptors on Human Airway Smooth Muscle Cells and Regulate the Release of Colony-Stimulating Factors by Activating cAMP-Dependent Protein Kinase
Mol Pharmacol 2005 67: 383-393. Published online November 4, 2004; 10.1124/mol.104.006486 [Abstract] [Full Text] [PDF]  

Susan Nowell, Bridgett Green, Yong Ming Tang, Rick Wiese, and Fred F. Kadlubar
Examination of Human Tissue Cytosols for Expression of Sulfotransferase Isoform 1A2 (SULT1A2) Using a SULT1A2-Specific Antibody
Mol Pharmacol 2005 67: 394-399. Published online November 4, 2004; 10.1124/mol.104.006171 [Abstract] [Full Text] [PDF]  

Maria Torvinen, Daniel Marcellino, Meritxell Canals, Luigi F. Agnati, Carmen Lluis, Rafael Franco, and Kjell Fuxe
Adenosine A2A Receptor and Dopamine D3 Receptor Interactions: Evidence of Functional A2A/D3 Heteromeric Complexes
Mol Pharmacol 2005 67: 400-407. Published online November 11, 2004; 10.1124/mol.104.003376 [Abstract] [Full Text] [PDF]  

Wing Lam, ChinShing Chen, Shuolun Ruan, Chung-Hang Leung, and Yung-Chi Cheng
Expression of Deoxynucleotide Carrier Is Not Associated with the Mitochondrial DNA Depletion Caused by Anti-HIV Dideoxynucleoside Analogs and Mitochondrial dNTP Uptake
Mol Pharmacol 2005 67: 408-416. Published online November 11, 2004; 10.1124/mol.104.007120 [Abstract] [Full Text] [PDF]  

Helen A. Seow, Michael F. Belcourt, Philip G. Penketh, William F. Hodnick, Maria Tomasz, Sara Rockwell, and Alan C. Sartorelli
Nuclear Localization of NADPH:Cytochrome c (P450) Reductase Enhances the Cytotoxicity of Mitomycin C to Chinese Hamster Ovary Cells
Mol Pharmacol 2005 67: 417-423. Published online November 16, 2004; 10.1124/mol.104.004929 [Abstract] [Full Text] [PDF]  

Suk Ying Tsang, Robert G. Tsushima, Gordon F. Tomaselli, Ronald A. Li, and Peter H. Backx
A Multifunctional Aromatic Residue in the External Pore Vestibule of Na+ Channels Contributes to the Local Anesthetic Receptor
Mol Pharmacol 2005 67: 424-434. [Abstract] [Full Text] [PDF]  

Silvio Bandiera, Simone Weidlich, Volker Harth, Peter Broede, Yun Ko, and Thomas Friedberg
Proteasomal Degradation of Human CYP1B1: Effect of the Asn453Ser Polymorphism on the Post-Translational Regulation of CYP1B1 Expression
Mol Pharmacol 2005 67: 435-443. Published online October 14, 2004; 10.1124/mol.104.006056 [Abstract] [Full Text] [PDF]  

A. Marchand, C. Tomkiewicz, J.-P. Marchandeau, E. Boitier, R. Barouki, and M. Garlatti
2,3,7,8-Tetrachlorodibenzo-p-dioxin Induces Insulin-Like Growth Factor Binding Protein-1 Gene Expression and Counteracts the Negative Effect of Insulin
Mol Pharmacol 2005 67: 444-452. Published online October 20, 2004; 10.1124/mol.104.004010 [Abstract] [Full Text] [PDF]  

Vijaya L. Damaraju, Katherine F. Hamilton, Michelle L. Seth-Smith, Carol E. Cass, and Michael B. Sawyer
Characterization of Binding of Folates and Antifolates to Brush-Border Membrane Vesicles Isolated from Human Kidney
Mol Pharmacol 2005 67: 453-459. Published online October 27, 2004; 10.1124/mol.104.004978 [Abstract] [Full Text] [PDF]  

Laïla El-Asmar, Jean-Yves Springael, Sébastien Ballet, Eneko Urizar Andrieu, Gilbert Vassart, and Marc Parmentier
Evidence for Negative Binding Cooperativity within CCR5-CCR2b Heterodimers
Mol Pharmacol 2005 67: 460-469. Published online October 27, 2004; 10.1124/mol.104.003624 [Abstract] [Full Text] [PDF]  

Haohua Qian, Yi Pan, Yujie Zhu, and Parham Khalili
Picrotoxin Accelerates Relaxation of GABAC Receptors
Mol Pharmacol 2005 67: 470-479. Published online October 27, 2004; 10.1124/mol.104.003996 [Abstract] [Full Text] [PDF] Reference added in Proof  

Sharon Tsuk, Izhak Michaelevski, Geoffrey N. Bentley, Rolf H. Joho, Dodo Chikvashvili, and Ilana Lotan
Kv2.1 Channel Activation and Inactivation Is Influenced by Physical Interactions of Both Syntaxin 1A and the Syntaxin 1A/Soluble N-Ethylmaleimide-Sensitive Factor-25 (t-SNARE) Complex with the C Terminus of the Channel
Mol Pharmacol 2005 67: 480-488. Published online November 3, 2004; 10.1124/mol.104.005314 [Abstract] [Full Text] [PDF]  

Ling-Lin Wang, Chen-Chun Ou, and Julie Y.H. Chan
Receptor-Independent Activation of GABAergic Neurotransmission and Receptor-Dependent Nontranscriptional Activation of Phosphatidylinositol 3-kinase/Protein Kinase Akt Pathway in Short-Term Cardiovascular Actions of Dexamethasone at the Nucleus Tractus Solitarii of the Rat
Mol Pharmacol 2005 67: 489-498. Published online November 2, 2004; 10.1124/mol.104.005595 [Abstract] [Full Text] [PDF]  

Wenchao Zheng and Colin R. Jefcoate
Steroidogenic Factor-1 Interacts with cAMP Response Element-Binding Protein to Mediate cAMP Stimulation of CYP1B1 via a Far Upstream Enhancer
Mol Pharmacol 2005 67: 499-512. Published online November 2, 2004; 10.1124/mol.104.005504 [Abstract] [Full Text] [PDF]  

Jianguo Tan, Zhiqi Liu, Ruiwu Wang, Zachary Y. Huang, Andrew C. Chen, Michael Gurevitz, and Ke Dong
Identification of Amino Acid Residues in the Insect Sodium Channel Critical for Pyrethroid Binding
Mol Pharmacol 2005 67: 513-522. Published online November 3, 2004; 10.1124/mol.104.006205 [Abstract] [Full Text] [PDF]  

Smitha Antony, Glenda Kohlhagen, Keli Agama, Muthusamy Jayaraman, Shousong Cao, Farukh A. Durrani, Youcef M. Rustum, Mark Cushman, and Yves Pommier
Cellular Topoisomerase I Inhibition and Antiproliferative Activity by MJ-III-65 (NSC 706744), an Indenoisoquinoline Topoisomerase I Poison
Mol Pharmacol 2005 67: 523-530. Published online November 5, 2004; 10.1124/mol.104.003889 [Abstract] [Full Text] [PDF]  

Jordi Martínez, Oliver Vögler, Jesús Casas, Francisca Barceló, Regina Alemany, Jesús Prades, Tünde Nagy, Carmela Baamonde, Philip G. Kasprzyk, Silvia Terés, Carlos Saus, and Pablo V. Escribá
Membrane Structure Modulation, Protein Kinase C{alpha} Activation, and Anticancer Activity of Minerval
Mol Pharmacol 2005 67: 531-540. Published online November 5, 2004; 10.1124/mol.104.000778 [Abstract] [Full Text] [PDF]  

A. Welling, F. Hofmann, and J. W. Wegener
Inhibition of L-Type Cav1.2 Ca2+ Channels by 2,(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002) and 2-[1-(3-Dimethyl-aminopropyl)-5-methoxyindol-3-yl]-3-(1H-indol-3-yl) Maleimide (Gö6983)
Mol Pharmacol 2005 67: 541-544. Published online November 10, 2004; 10.1124/mol.104.006049 [Abstract] [Full Text] [PDF]  

Zhe-Sheng Chen, Yanping Guo, Martin G. Belinsky, Elena Kotova, and Gary D. Kruh
Transport of Bile Acids, Sulfated Steroids, Estradiol 17-{beta}-D-Glucuronide, and Leukotriene C4 by Human Multidrug Resistance Protein 8 (ABCC11)
Mol Pharmacol 2005 67: 545-557. Published online November 10, 2004; 10.1124/mol.104.007138 [Abstract] [Full Text] [PDF]  

Mohamed Trebak, Nadine Hempel, Barbara J. Wedel, Jeremy T. Smyth, Gary St. J. Bird, and James W. Putney, Jr.
Negative Regulation of TRPC3 Channels by Protein Kinase C-Mediated Phosphorylation of Serine 712
Mol Pharmacol 2005 67: 558-563. Published online November 8, 2004; 10.1124/mol.104.007252 [Abstract] [Full Text] [PDF]  

Qingming Ding, Robert Gros, Jozef Chorazyczewski, Stephen S. G. Ferguson, and Ross D. Feldman
Isoform-Specific Regulation of Adenylyl Cyclase Function by Disruption of Membrane Trafficking
Mol Pharmacol 2005 67: 564-571. Published online November 16, 2004; 10.1124/mol.104.006817 [Abstract] [Full Text] [PDF]  

Lucio Tentori, Olindo Forini, Emanuela Fossile, Alessia Muzi, Matteo Vergati, Ilaria Portarena, Carla Amici, Barry Gold, and Grazia Graziani
N3-Methyladenine Induces Early Poly(ADP-Ribosylation), Reduction of Nuclear Factor-{kappa}B DNA Binding Ability, and Nuclear Up-Regulation of Telomerase Activity
Mol Pharmacol 2005 67: 572-581. Published online November 17, 2004; 10.1124/mol.104.004937 [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

About the Cover Stereo image of a side and top view of a refined P-gp (model B). See the article by Pleban et al. on page 365 of this issue.



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