Minireview:

X. Xu, H. L. Persson, and D. R. Richardson

Molecular Pharmacology of the Interaction of Anthracyclines with Iron
Mol Pharmacol 2005 68: 261-271. Published online May 9, 2005; 10.1124/mol.105.013383 [Abstract] [Full Text] [PDF]  

Perspectives:

Arnold E. Ruoho

How the Monoamine Transporter Garden Grows
Mol Pharmacol 2005 68: 272-274. Published online May 23, 2005; 10.1124/mol.105.014951 [Abstract] [Full Text] [PDF] Related Article  

Kim A. Neve

Double Feature at the Signalplex
Mol Pharmacol 2005 68: 275-278. Published online May 27, 2005; 10.1124/mol.105.015263 [Abstract] [Full Text] [PDF] Related Article  

Accelerated Communications:

Qifang Wu, Cheol Kyu Hwang, Shiyi Yao, Ping-Yee Law, Horace H. Loh, and Li-Na Wei

A Major Species of Mouse µ-opioid Receptor mRNA and Its Promoter-Dependent Functional Polyadenylation Signal
Mol Pharmacol 2005 68: 279-285. Published online May 6, 2005; 10.1124/mol.105.012567 [Abstract] [Full Text] [PDF]  

Articles:

Chung-Hang Leung, Susan P. Grill, Wing Lam, Quan-Bin Han, Han-Dong Sun, and Yung-Chi Cheng

Novel Mechanism of Inhibition of Nuclear Factor-B DNA-Binding Activity by Diterpenoids Isolated from Isodon rubescens
Mol Pharmacol 2005 68: 286-297. Published online May 4, 2005; 10.1124/mol.105.012765 [Abstract] [Full Text] [PDF]  

G. Loussouarn, L. J. Marton, and C. G. Nichols

Molecular Basis of Inward Rectification: Structural Features of the Blocker Defined by Extended Polyamine Analogs
Mol Pharmacol 2005 68: 298-304. Published online May 4, 2005; 10.1124/mol.105.012377 [Abstract] [Full Text] [PDF]  

Daniel Herrera, Aida Mamarbachi, Manuel Simoes, Lucie Parent, Rémy Sauvé, Zhiguo Wang, and Stanley Nattel

A Single Residue in the S6 Transmembrane Domain Governs the Differential Flecainide Sensitivity of Voltage-Gated Potassium Channels
Mol Pharmacol 2005 68: 305-316. Published online May 9, 2005; 10.1124/mol.104.009506 [Abstract] [Full Text] [PDF]  

Maen Abdelrahim and Stephen Safe

Cyclooxygenase-2 Inhibitors Decrease Vascular Endothelial Growth Factor Expression in Colon Cancer Cells by Enhanced Degradation of Sp1 and Sp4 Proteins
Mol Pharmacol 2005 68: 317-329. Published online May 9, 2005; 10.1124/mol.105.011825 [Abstract] [Full Text] [PDF]  

Benjamin J. Pettus, Kazuyuki Kitatani, Charles E. Chalfant, Tarek A. Taha, Toshihiko Kawamori, Jacek Bielawski, Lina M. Obeid, and Yusuf A. Hannun

The Coordination of Prostaglandin E₂ Production by Sphingosine-1-phosphate and Ceramide-1-phosphate
Mol Pharmacol 2005 68: 330-335. Published online May 17, 2005; 10.1124/mol.104.008722 [Abstract] [Full Text] [PDF]  

Simone Kann, Ming-ya Huang, Cameron Estes, John F. Reichard, Maureen A. Sartor, Ying Xia, and Alvaro Puga

Arsenite-Induced Aryl Hydrocarbon Receptor Nuclear Translocation Results in Additive Induction of Phase I Genes and Synergistic Induction of Phase II Genes
Mol Pharmacol 2005 68: 336-346. Published online May 13, 2005; 10.1124/mol.105.011841 [Abstract] [Full Text] [PDF]  

Ying-Hong Feng, Lingyin Zhou, Rongde Qiu, and Robin Zeng

Single Mutations at Asn²⁹⁵ and Leu³⁰⁵ in the Cytoplasmic Half of Transmembrane -Helix Domain 7 of the AT₁ Receptor Induce Promiscuous Agonist Specificity for Angiotensin II Fragments: A Pseudo-Constitutive Activity
Mol Pharmacol 2005 68: 347-355. Published online May 18, 2005; 10.1124/mol.105.011601 [Abstract] [Full Text] [PDF]  

J. Alberto Olivares-Reyes, Bukhtiar H. Shah, Judith Hernández-Aranda, Agustín García-Caballero, M. Parvaiz Farshori, J. Adolfo García-Sáinz, and Kevin J. Catt

Agonist-Induced Interactions between Angiotensin AT₁ and Epidermal Growth Factor Receptors
Mol Pharmacol 2005 68: 356-364. Published online May 19, 2005; 10.1124/mol.104.010637 [Abstract] [Full Text] [PDF]  

Dong Yan and Michael M. White

Spatial Orientation of the Antagonist Granisetron in the Ligand-Binding Site of the 5-HT₃ Receptor
Mol Pharmacol 2005 68: 365-371. Published online May 24, 2005; 10.1124/mol.105.011957 [Abstract] [Full Text] [PDF]  

Riku Koivusalo, Eberhard Krausz, Hans Helenius, and Sakari Hietanen

Chemotherapy Compounds in Cervical Cancer Cells Primed by Reconstitution of p53 Function after Short Interfering RNA-Mediated Degradation of Human Papillomavirus 18 E6 mRNA: Opposite Effect of siRNA in Combination with Different Drugs
Mol Pharmacol 2005 68: 372-382. Published online May 20, 2005; 10.1124/mol.105.011189 [Abstract] [Full Text] [PDF] Data Supplement  

Sevasti B. Koukouritaki, Mark T. Poch, Erwin T. Cabacungan, D. Gail McCarver, and Ronald N. Hines

Discovery of Novel Flavin-Containing Monooxygenase 3 (FMO3) Single Nucleotide Polymorphisms and Functional Analysis of Upstream Haplotype Variants
Mol Pharmacol 2005 68: 383-392. Published online April 27, 2005; 10.1124/mol.105.012062 [Abstract] [Full Text] [PDF]  

Jesper Mosolff Mathiesen, Trond Ulven, Lene Martini, Lars Ole Gerlach, Akos Heinemann, and Evi Kostenis

Identification of Indole Derivatives Exclusively Interfering with a G Protein-Independent Signaling Pathway of the Prostaglandin D2 Receptor CRTH2
Mol Pharmacol 2005 68: 393-402. Published online May 3, 2005; 10.1124/mol.104.010520 [Abstract] [Full Text] [PDF]  

Ying Mu, Corey R. J. Stephenson, Christopher Kendall, Simrat P. S. Saini, David Toma, Songrong Ren, Hongbo Cai, Stephen C. Strom, Billy W. Day, Peter Wipf, and Wen Xie

A Pregnane X Receptor Agonist with Unique Species-Dependent Stereoselectivity and Its Implications in Drug Development
Mol Pharmacol 2005 68: 403-413. Published online May 4, 2005; 10.1124/mol.105.013292 [Abstract] [Full Text] [PDF]  

Sachiko Maeda, Isao Matsuoka, Takahiro Iwamoto, Hitoshi Kurose, and Junko Kimura

Down-Regulation of Na⁺/Ca²⁺ Exchanger by Fluvastatin in Rat Cardiomyoblast H9c2 Cells: Involvement of RhoB in Na⁺/Ca²⁺ Exchanger mRNA Stability
Mol Pharmacol 2005 68: 414-420. Published online May 6, 2005; 10.1124/mol.104.000786 [Abstract] [Full Text] [PDF]  

Vincent Pascoli, Emmanuel Valjent, Anne-Gaëlle Corbillé, Jean-Christophe Corvol, Jean-Pol Tassin, Jean-Antoine Girault, and Denis Hervé

cAMP and Extracellular Signal-Regulated Kinase Signaling in Response to D-Amphetamine and Methylphenidate in the Prefrontal Cortex in Vivo: Role of 1-Adrenoceptors
Mol Pharmacol 2005 68: 421-429. Published online May 12, 2005; 10.1124/mol.105.011809 [Abstract] [Full Text] [PDF]  

Yang Liu, Hui Peng, and Jian-Ting Zhang

Expression Profiling of ABC Transporters in a Drug-Resistant Breast Cancer Cell Line Using AmpArray
Mol Pharmacol 2005 68: 430-438. Published online May 18, 2005; 10.1124/mol.105.011015 [Abstract] [Full Text] [PDF]  

Jane L. Rose, Hong Huang, Scott F. Wray, and Dale G. Hoyt

Integrin Engagement Increases Histone H3 Acetylation and Reduces Histone H1 Association with DNA in Murine Lung Endothelial Cells
Mol Pharmacol 2005 68: 439-446. Published online May 18, 2005; 10.1124/mol.104.010876 [Abstract] [Full Text] [PDF]  

Hatice Z. Ozsoy, Deepak R. Thakker, and Kelly M. Standifer

Orphanin FQ/Nociceptin Potentiates [D-Ala²,N-Me-Phe⁴,Gly⁵-ol]-Enkephalin–Induced µ-Opioid Receptor Phosphorylation
Mol Pharmacol 2005 68: 447-456. Published online May 12, 2005; 10.1124/mol.105.011536 [Abstract] [Full Text] [PDF]  

Maureen K. Hahn, Michelle S. Mazei-Robison, and Randy D. Blakely

Single Nucleotide Polymorphisms in the Human Norepinephrine Transporter Gene Affect Expression, Trafficking, Antidepressant Interaction, and Protein Kinase C Regulation
Mol Pharmacol 2005 68: 457-466. Published online May 13, 2005; 10.1124/mol.105.011270 [Abstract] [Full Text] [PDF]  

Lionel Moulédous, Jérémie Neasta, Sandrine Uttenweiler-Joseph, Alexandre Stella, Mariette Matondo, Maïthé Corbani, Bernard Monsarrat, and Jean-Claude Meunier

Long-Term Morphine Treatment Enhances Proteasome-Dependent Degradation of G in Human Neuroblastoma SH-SY5Y Cells: Correlation with Onset of Adenylate Cyclase Sensitization
Mol Pharmacol 2005 68: 467-476. Published online May 18, 2005; 10.1124/mol.105.013391 [Abstract] [Full Text] [PDF]  

Laura M. Bruzek, Jenny N. Poynter, Scott H. Kaufmann, and Alex A. Adjei

Characterization of a Human Carcinoma Cell Line Selected for Resistance to the Farnesyl Transferase Inhibitor 4-(2-(4-(8-Chloro-3,10-dibromo-6,11-dihydro-5H-benzo-(5,6)-cyclohepta(1,2-b)-pyridin-11(R)-yl)-1-piperidinyl)-2-oxo-ethyl)-1-piperidinecarboxamide (SCH66336)
Mol Pharmacol 2005 68: 477-486. Published online May 18, 2005; 10.1124/mol.104.010074 [Abstract] [Full Text] [PDF]  

Nivalda O. Rodrigues-Pinguet, Thierry J. Pinguet, Antonio Figl, Henry A. Lester, and Bruce N. Cohen

Mutations Linked to Autosomal Dominant Nocturnal Frontal Lobe Epilepsy Affect Allosteric Ca²⁺ Activation of the 42 Nicotinic Acetylcholine Receptor
Mol Pharmacol 2005 68: 487-501. Published online May 18, 2005; 10.1124/mol.105.011155 [Abstract] [Full Text] [PDF] Data Supplement  

Maarten L. Janmaat, José A. Rodriguez, José Jimeno, Frank A. E. Kruyt, and Giuseppe Giaccone

Kahalalide F Induces Necrosis-Like Cell Death that Involves Depletion of ErbB3 and Inhibition of Akt Signaling
Mol Pharmacol 2005 68: 502-510. Published online May 20, 2005; 10.1124/mol.105.011361 [Abstract] [Full Text] [PDF]  

Rajesh S. Savkur, Kelli S. Bramlett, Keith R. Stayrook, Sunil Nagpal, and Thomas P. Burris

Coactivation of the Human Vitamin D Receptor by the Peroxisome Proliferator-Activated Receptor Coactivator-1
Mol Pharmacol 2005 68: 511-517. Published online May 20, 2005; 10.1124/mol.105.012708 [Abstract] [Full Text] [PDF]  

Annette Weil, Stephen E. Moore, Nicola J. Waite, Andrew Randall, and Martin J. Gunthorpe

Conservation of Functional and Pharmacological Properties in the Distantly Related Temperature Sensors TRVP1 and TRPM8
Mol Pharmacol 2005 68: 518-527. Published online May 23, 2005; 10.1124/mol.105.012146 [Abstract] [Full Text] [PDF] Erratum  

Qingwei Luo, Yun Ding, Kurt Watson, Jingwu Zhang, and Guo-Huang Fan

N-Methyl-D-aspartate Attenuates CXCR2-Mediated Neuroprotection through Enhancing the Receptor Phosphorylation and Blocking the Receptor Recycling
Mol Pharmacol 2005 68: 528-537. Published online May 24, 2005; 10.1124/mol.105.011197 [Abstract] [Full Text] [PDF]  

Giada A. Locatelli, Roberto Di Santo, Emmanuele Crespan, Roberta Costi, Alessandra Roux, Ulrich Hübscher, Igor Shevelev, Giuseppina Blanca, Giuseppe Villani, Silvio Spadari, and Giovanni Maga

Diketo Hexenoic Acid Derivatives Are Novel Selective Non-Nucleoside Inhibitors of Mammalian Terminal Deoxynucleotidyl Transferases, with Potent Cytotoxic Effect against Leukemic Cells
Mol Pharmacol 2005 68: 538-550. Published online May 18, 2005; 10.1124/mol.105.013326 [Abstract] [Full Text] [PDF]  

Giovanni Rizzo, Barbara Renga, Elisabetta Antonelli, Daniela Passeri, Roberto Pellicciari, and Stefano Fiorucci

The Methyl Transferase PRMT1 Functions as Co-Activator of Farnesoid X Receptor (FXR)/9-cis Retinoid X Receptor and Regulates Transcription of FXR Responsive Genes
Mol Pharmacol 2005 68: 551-558. Published online May 23, 2005; 10.1124/mol.105.012104 [Abstract] [Full Text] [PDF] Data Supplement  

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