Perspective:

Angela M. Finch and Robert M. Graham

The _1D-Adrenergic Receptor: Cinderella or Ugly Stepsister
Mol Pharmacol 2006 69: 1-4. Published online October 24, 2005; 10.1124/mol.105.020230 [Abstract] [Full Text] [PDF] [RELATED ARTICLE]   

Accelerated Communication:

Hiromichi Fujino and John W. Regan

EP₄ Prostanoid Receptor Coupling to a Pertussis Toxin-Sensitive Inhibitory G Protein
Mol Pharmacol 2006 69: 5-10. Published online October 4, 2005; 10.1124/mol.105.017749 [Abstract] [Full Text] [PDF]  

Articles:

Yalini Arinaminpathy, Mark S. P. Sansom, and Philip C. Biggin

Binding Site Flexibility: Molecular Simulation of Partial and Full Agonists within a Glutamate Receptor
Mol Pharmacol 2006 69: 11-18. Published online October 11, 2005; 10.1124/mol.105.016691 [Abstract] [Full Text] [PDF] [Data Supplement]   

Karin Kohlstedt, Roland Kellner, Rudi Busse, and Ingrid Fleming

Signaling via the Angiotensin-Converting Enzyme Results in the Phosphorylation of the Nonmuscle Myosin Heavy Chain IIA
Mol Pharmacol 2006 69: 19-26. Published online September 26, 2005; 10.1124/mol.105.016733 [Abstract] [Full Text] [PDF]  

Bernard Hsiao, Karla B. Mihalak, Sarah E. Repicky, Drew Everhart, Ana H. Mederos, Arun Malhotra, and Charles W. Luetje

Determinants of Zinc Potentiation on the 4 Subunit of Neuronal Nicotinic Receptors
Mol Pharmacol 2006 69: 27-36. Published online September 27, 2005; 10.1124/mol.105.015164 [Abstract] [Full Text] [PDF]  

Barbara Costa, Alessandra Salvetti, Leonardo Rossi, Francesca Spinetti, Annalisa Lena, Beatrice Chelli, Mariarosa Rechichi, Eleonora Da Pozzo, Vittorio Gremigni, and Claudia Martini

Peripheral Benzodiazepine Receptor: Characterization in Human T-Lymphoma Jurkat Cells
Mol Pharmacol 2006 69: 37-44. Published online September 27, 2005; 10.1124/mol.105.015289 [Abstract] [Full Text] [PDF]  

Chris Hague, Sarah E. Lee, Zhongjian Chen, Steven C. Prinster, Randy A. Hall, and Kenneth P. Minneman

Heterodimers of _1B- and _1D-Adrenergic Receptors Form a Single Functional Entity
Mol Pharmacol 2006 69: 45-55. Published online September 29, 2005; 10.1124/mol.105.014985 [Abstract] [Full Text] [PDF]  

Yang Xu, Takanori Hashizume, Margaret C. Shuhart, Connie L. Davis, Wendel L. Nelson, Toshiyuki Sakaki, Thomas F. Kalhorn, Paul B. Watkins, Erin G. Schuetz, and Kenneth E. Thummel

Intestinal and Hepatic CYP3A4 Catalyze Hydroxylation of 1,25-Dihydroxyvitamin D₃: Implications for Drug-Induced Osteomalacia
Mol Pharmacol 2006 69: 56-65. Published online October 5, 2005; 10.1124/mol.105.017392 [Abstract] [Full Text] [PDF]  

Ming Zhao, Richard G. DiScipio, Antonia G. Wimmer, and Ingrid U. Schraufstatter

Regulation of CXCR4-Mediated Nuclear Translocation of Extracellular Signal-Related Kinases 1 and 2
Mol Pharmacol 2006 69: 66-75. Published online October 6, 2005; 10.1124/mol.105.016923 [Abstract] [Full Text] [PDF]  

Yuyoung Joo, Hye-Sun Kim, Ran-Sook Woo, Cheol Hyoung Park, Ki-Young Shin, Jean-Pyo Lee, Keun-A Chang, Seonghan Kim, and Yoo-Hun Suh

Mefenamic Acid Shows Neuroprotective Effects and Improves Cognitive Impairment in in Vitro and in Vivo Alzheimer's Disease Models
Mol Pharmacol 2006 69: 76-84. Published online October 13, 2005; 10.1124/mol.105.015206 [Abstract] [Full Text] [PDF]  

Ying-Nai Wang, Yun-Ju Chen, and Wen-Chang Chang

Activation of Extracellular Signal-Regulated Kinase Signaling by Epidermal Growth Factor Mediates c-Jun Activation and p300 Recruitment in Keratin 16 Gene Expression
Mol Pharmacol 2006 69: 85-98. Published online October 7, 2005; 10.1124/mol.105.016220 [Abstract] [Full Text] [PDF]  

David R. Johnson, Chia-Wei Li, Liuh-Yow Chen, Jagadish C. Ghosh, and J. Don Chen

Regulation and Binding of Pregnane X Receptor by Nuclear Receptor Corepressor Silencing Mediator of Retinoid and Thyroid Hormone Receptors (SMRT)
Mol Pharmacol 2006 69: 99-108. Published online October 11, 2005; 10.1124/mol.105.013375 [Abstract] [Full Text] [PDF]  

Vahideh Lamian, Adam Rich, Zhengping Ma, James Li, Ramakrishna Seethala, David Gordon, and Yves Dubaquie

Characterization of Agonist-Induced Motilin Receptor Trafficking and Its Implications for Tachyphylaxis
Mol Pharmacol 2006 69: 109-118. Published online October 12, 2005; 10.1124/mol.105.017111 [Abstract] [Full Text] [PDF]  

Carsten Schmidt, Markus Werner, and Michael Hollmann

Revisiting the Postulated "Unitary Glutamate Receptor": Electrophysiological and Pharmacological Analysis in Two Heterologous Expression Systems Fails to Detect Evidence for Its Existence
Mol Pharmacol 2006 69: 119-129. Published online October 7, 2005; 10.1124/mol.105.016840 [Abstract] [Full Text] [PDF]  

Chrysoula Leontiou, Jeremy H. Lakey, Robert Lightowlers, Rozalind M. Turnbull, and Caroline A. Austin

Mutation P732L in Human DNA Topoisomerase II Abolishes DNA Cleavage in the Presence of Calcium and Confers Drug Resistance
Mol Pharmacol 2006 69: 130-139. Published online October 20, 2005; 10.1124/mol.105.015933 [Abstract] [Full Text] [PDF]  

Nathalie Tijet, Paul C. Boutros, Ivy D. Moffat, Allan B. Okey, Jouko Tuomisto, and Raimo Pohjanvirta

Aryl Hydrocarbon Receptor Regulates Distinct Dioxin-Dependent and Dioxin-Independent Gene Batteries
Mol Pharmacol 2006 69: 140-153. Published online October 7, 2005; 10.1124/mol.105.018705 [Abstract] [Full Text] [PDF] [Data Supplement] [Erratum]   

Jui-I Chao and Huei-Fang Liu

The Blockage of Survivin and Securin Expression Increases the Cytochalasin B-Induced Cell Death and Growth Inhibition in Human Cancer Cells
Mol Pharmacol 2006 69: 154-164. Published online October 11, 2005; 10.1124/mol.105.015503 [Abstract] [Full Text] [PDF]  

Antonella Liantonio, Alessandra Picollo, Elena Babini, Giuseppe Carbonara, Giuseppe Fracchiolla, Fulvio Loiodice, Vincenzo Tortorella, Michael Pusch, and Diana Conte Camerino

Activation and Inhibition of Kidney CLC-K Chloride Channels by Fenamates
Mol Pharmacol 2006 69: 165-173. Published online October 21, 2005; 10.1124/mol.105.017384 [Abstract] [Full Text] [PDF]  

Peter J. Atkinson, Kenneth W. Young, Steven J. Ennion, James N. C. Kew, Stefan R. Nahorski, and R. A. John Challiss

Altered Expression of G_q/11 Protein Shapes mGlu1 and mGlu5 Receptor-Mediated Single Cell Inositol 1,4,5-Trisphosphate and Ca²⁺ Signaling
Mol Pharmacol 2006 69: 174-184. Published online October 18, 2005; 10.1124/mol.105.014258 [Abstract] [Full Text] [PDF]  

Hongxiang Lan, Curtiss J. DuRand, Martha M. Teeter, and Kim A. Neve

Structural Determinants of Pharmacological Specificity Between D₁ and D₂ Dopamine Receptors
Mol Pharmacol 2006 69: 185-194. Published online October 19, 2005; 10.1124/mol.105.017244 [Abstract] [Full Text] [PDF]  

Sita Aggarwal, Haruyo Ichikawa, Yasunari Takada, Santosh K. Sandur, Shishir Shishodia, and Bharat B. Aggarwal

Curcumin (Diferuloylmethane) Down-Regulates Expression of Cell Proliferation and Antiapoptotic and Metastatic Gene Products through Suppression of IB Kinase and Akt Activation
Mol Pharmacol 2006 69: 195-206. Published online October 11, 2005; 10.1124/mol.105.017400 [Abstract] [Full Text] [PDF]  

Kjetil Wessel Andressen, Jens Henrik Norum, Finn Olav Levy, and Kurt A. Krobert

Activation of Adenylyl Cyclase by Endogenous G_s-Coupled Receptors in Human Embryonic Kidney 293 Cells Is Attenuated by 5-HT₇ Receptor Expression
Mol Pharmacol 2006 69: 207-215. Published online September 27, 2005; 10.1124/mol.105.015396 [Abstract] [Full Text] [PDF]  

Roberto R. Rosato, Sonia C. Maggio, Jorge A. Almenara, Shawn G. Payne, Peter Atadja, Sarah Spiegel, Paul Dent, and Steven Grant

The Histone Deacetylase Inhibitor LAQ824 Induces Human Leukemia Cell Death through a Process Involving XIAP Down-Regulation, Oxidative Injury, and the Acid Sphingomyelinase-Dependent Generation of Ceramide
Mol Pharmacol 2006 69: 216-225. Published online September 27, 2005; 10.1124/mol.105.017145 [Abstract] [Full Text] [PDF]  

Meritxell Vivo, Hong Lin, and Philip G. Strange

Investigation of Cooperativity in the Binding of Ligands to the D₂ Dopamine Receptor
Mol Pharmacol 2006 69: 226-235. Published online October 4, 2005; 10.1124/mol.105.012443 [Abstract] [Full Text] [PDF]  

Christopher J. Langmead, Victoria A. H. Fry, Ian T. Forbes, Clive L. Branch, Arthur Christopoulos, Martyn D. Wood, and Hugh J. Herdon

Probing the Molecular Mechanism of Interaction between 4-n-Butyl-1-[4-(2-methylphenyl)-4-oxo-1-butyl]-piperidine (AC-42) and the Muscarinic M₁ Receptor: Direct Pharmacological Evidence That AC-42 Is an Allosteric Agonist
Mol Pharmacol 2006 69: 236-246. Published online October 5, 2005; 10.1124/mol.105.017814 [Abstract] [Full Text] [PDF]  

Yuliya Dobrydneva, Christopher J. Abelt, Beth Dovel, Celina M. Thadigiri, Roy L. Williams, and Peter F. Blackmore

2-Aminoethoxydiphenyl Borate as a Prototype Drug for a Group of Structurally Related Calcium Channel Blockers in Human Platelets
Mol Pharmacol 2006 69: 247-256. Published online October 7, 2005; 10.1124/mol.105.015701 [Abstract] [Full Text] [PDF]  

Lijoy K. Mathew, Eric A. Andreasen, and Robert L. Tanguay

Aryl Hydrocarbon Receptor Activation Inhibits Regenerative Growth
Mol Pharmacol 2006 69: 257-265. Published online October 7, 2005; 10.1124/mol.105.018044 [Abstract] [Full Text] [PDF]  

Rie Schultz Hansen, Thomas Goldin Diness, Torsten Christ, Joachim Demnitz, Ursula Ravens, Søren-Peter Olesen, and Morten Grunnet

Activation of Human ether-a-go-go-Related Gene Potassium Channels by the Diphenylurea 1,3-Bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643)
Mol Pharmacol 2006 69: 266-277. Published online October 11, 2005; 10.1124/mol.105.015859 [Abstract] [Full Text] [PDF]  

Dieter R. Riddall, Michael J. Leach, and John Garthwaite

A Novel Drug Binding Site on Voltage-Gated Sodium Channels in Rat Brain
Mol Pharmacol 2006 69: 278-287. Published online October 11, 2005; 10.1124/mol.105.015966 [Abstract] [Full Text] [PDF]  

Girija Dasmahapatra, Jorge A. Almenara, and Steven Grant

Flavopiridol and Histone Deacetylase Inhibitors Promote Mitochondrial Injury and Cell Death in Human Leukemia Cells That Overexpress Bcl-2
Mol Pharmacol 2006 69: 288-298. Published online October 11, 2005; 10.1124/mol.105.016154 [Abstract] [Full Text] [PDF]  

Shiu-Hwa Yeh, Sheng-Chun Mao, Hui-Ching Lin, and Po-Wu Gean

Synaptic Expression of Glutamate Receptor after Encoding of Fear Memory in the Rat Amygdala
Mol Pharmacol 2006 69: 299-308. Published online October 11, 2005; 10.1124/mol.105.017194 [Abstract] [Full Text] [PDF]  

Christopher A. Haskell, Richard Horuk, Meina Liang, Mary Rosser, Laura Dunning, Imadul Islam, Leonor Kremer, Julio Gutiérrez, Gabriel Marquez, Carlos Martinez-A, Mark J. Biscone, Robert W. Doms, and Sofia Ribeiro

Identification and Characterization of a Potent, Selective Nonpeptide Agonist of the CC Chemokine Receptor CCR8
Mol Pharmacol 2006 69: 309-316. Published online October 12, 2005; 10.1124/mol.105.014779 [Abstract] [Full Text] [PDF]  

Robert Gros, Qingming Ding, Jozef Chorazyczewski, Joseph Andrews, J. Geoffrey Pickering, Robert A. Hegele, and Ross D. Feldman

The Impact of Blunted -Adrenergic Responsiveness on Growth Regulatory Pathways in Hypertension
Mol Pharmacol 2006 69: 317-327. Published online October 13, 2005; 10.1124/mol.105.013953 [Abstract] [Full Text] [PDF]  

Andreas Strub, Wolf-Rüdiger Ulrich, Christian Hesslinger, Manfrid Eltze, Thomas Fuchß, Jochen Strassner, Susanne Strand, Martin D. Lehner, and Rainer Boer

The Novel Imidazopyridine 2-[2-(4-Methoxy-pyridin-2-yl)-ethyl]-3H-imidazo[4,5-b]pyridine (BYK191023) Is a Highly Selective Inhibitor of the Inducible Nitric-Oxide Synthase
Mol Pharmacol 2006 69: 328-337. Published online October 13, 2005; 10.1124/mol.105.017087 [Abstract] [Full Text] [PDF]  

Zhongren Ding, Soochong Kim, and Satya P. Kunapuli

Identification of a Potent Inverse Agonist at a Constitutively Active Mutant of Human P2Y₁₂ Receptor
Mol Pharmacol 2006 69: 338-345. Published online October 18, 2005; 10.1124/mol.105.014654 [Abstract] [Full Text] [PDF]  

Karen M. King, Vijaya L. Damaraju, Mark F. Vickers, Sylvia Y. Yao, Thach Lang, Tracey E. Tackaberry, Delores A. Mowles, Amy M. L. Ng, James D. Young, and Carol E. Cass

A Comparison of the Transportability, and Its Role in Cytotoxicity, of Clofarabine, Cladribine, and Fludarabine by Recombinant Human Nucleoside Transporters Produced in Three Model Expression Systems
Mol Pharmacol 2006 69: 346-353. Published online October 18, 2005; 10.1124/mol.105.015768 [Abstract] [Full Text] [PDF]  

Stéphanie Mouhat, Georgeta Teodorescu, Daniel Homerick, Violeta Visan, Heike Wulff, Yingliang Wu, Stephan Grissmer, Hervé Darbon, Michel De Waard, and Jean-Marc Sabatier

Pharmacological Profiling of Orthochirus scrobiculosus Toxin 1 Analogs with a Trimmed N-Terminal Domain
Mol Pharmacol 2006 69: 354-362. Published online October 18, 2005; 10.1124/mol.105.017210 [Abstract] [Full Text] [PDF]  

Kaleeckal G. Harikumar, Maria M. Morfis, Cayle S. Lisenbee, Patrick M. Sexton, and Laurence J. Miller

Constitutive Formation of Oligomeric Complexes between Family B G Protein-Coupled Vasoactive Intestinal Polypeptide and Secretin Receptors
Mol Pharmacol 2006 69: 363-373. Published online October 21, 2005; 10.1124/mol.105.015776 [Abstract] [Full Text] [PDF]  

Gillian Borland, Mona Gupta, Maria M. Magiera, Catherine J. Rundell, Suzanne Fuld, and Stephen J. Yarwood

Microtubule-Associated Protein 1B-Light Chain 1 Enhances Activation of Rap1 by Exchange Protein Activated by Cyclic AMP but Not Intracellular Targeting
Mol Pharmacol 2006 69: 374-384. Published online October 21, 2005; 10.1124/mol.105.016337 [Abstract] [Full Text] [PDF]  

Seung Jin Lee and Sang Geon Kim

Role of p90 Ribosomal S6-Kinase-1 in Oltipraz-Induced Specific Phosphorylation of CCAAT/Enhancer Binding Protein- for GSTA2 Gene Transactivation
Mol Pharmacol 2006 69: 385-396. Published online October 24, 2005; 10.1124/mol.105.018465 [Abstract] [Full Text] [PDF] [Data Supplement]   

Christian Nanoff, Romana Koppensteiner, Qiong Yang, Elisabeth Fuerst, Horst Ahorn, and Michael Freissmuth

The Carboxyl Terminus of the G-Subunit Is the Latch for Triggered Activation of Heterotrimeric G Proteins
Mol Pharmacol 2006 69: 397-405. Published online October 6, 2005; 10.1124/mol.105.016725 [Abstract] [Full Text] [PDF]  

Errata:

Correction to "Different Structural States of the Proteolipid Membrane Are Produced by Ligand Binding to the Human -Opioid Receptor as Shown by Plasmon-Waveguide Resonance Spectroscopy"
Mol Pharmacol 2006 69: 406. [Full Text] [PDF]  

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.