Perspectives:

Kim A. Neve

Novel Features of G Protein-Coupled Receptor Kinase 4
Mol Pharmacol 2006 69: 673-676. Published online December 9, 2005; 10.1124/mol.105.021535 [Abstract] [Full Text] [PDF] [Related Article]   

Matthew L. Bilodeau and Heidi E. Hamm

Endothelial Nitric-Oxide Synthase Reveals a New Face in G Protein Signaling
Mol Pharmacol 2006 69: 677-679. Published online December 23, 2005; 10.1124/mol.105.022038 [Abstract] [Full Text] [PDF] [Related Article]   

Articles:

Magali Foucaud, Irina G. Tikhonova, Ingrid Langer, Chantal Escrieut, Marlène Dufresne, Cathy Seva, Bernard Maigret, and Daniel Fourmy

Partial Agonism, Neutral Antagonism, and Inverse Agonism at the Human Wild-Type and Constitutively Active Cholecystokinin-2 Receptors
Mol Pharmacol 2006 69: 680-690. Published online November 17, 2005; 10.1124/mol.105.019992 [Abstract] [Full Text] [PDF]  

Sun Hee Kim, Seok Joon Won, Xiao Ou Mao, Kunlin Jin, and David A. Greenberg

Molecular Mechanisms of Cannabinoid Protection from Neuronal Excitotoxicity
Mol Pharmacol 2006 69: 691-696. Published online November 18, 2005; 10.1124/mol.105.016428 [Abstract] [Full Text] [PDF]  

Tatyana Chernova, Pierluigi Nicotera, and Andrew G. Smith

Heme Deficiency Is Associated with Senescence and Causes Suppression of N-Methyl-D-aspartate Receptor Subunits Expression in Primary Cortical Neurons
Mol Pharmacol 2006 69: 697-705. Published online November 23, 2005; 10.1124/mol.105.016675 [Abstract] [Full Text] [PDF]  

Cui Ping Chen, Peter Kuhn, Kirti Chaturvedi, Nadka Boyadjieva, and Dipak K. Sarkar

Ethanol Induces Apoptotic Death of Developing -Endorphin Neurons via Suppression of Cyclic Adenosine Monophosphate Production and Activation of Transforming Growth Factor-1-Linked Apoptotic Signaling
Mol Pharmacol 2006 69: 706-717. Published online December 2, 2005; 10.1124/mol.105.017004 [Abstract] [Full Text] [PDF]  

Earl Gordon, Jaime-Lee Cohen, Robert Engel, and Geoffrey W. Abbott

1,4-Diazabicyclo[2.2.2]octane Derivatives: A Novel Class of Voltage-Gated Potassium Channel Blockers
Mol Pharmacol 2006 69: 718-726. Published online November 29, 2005; 10.1124/mol.105.018663 [Abstract] [Full Text] [PDF]  

Anna Maria D'Ursi, Laura Giusti, Stefania Albrizio, Francesca Porchia, Cinzia Esposito, Gabriella Caliendo, Claudia Gargini, Ettore Novellino, Antonio Lucacchini, Paolo Rovero, and Maria Rosa Mazzoni

A Membrane-Permeable Peptide Containing the Last 21 Residues of the G_S Carboxyl Terminus Inhibits G_S-Coupled Receptor Signaling in Intact Cells: Correlations between Peptide Structure and Biological Activity
Mol Pharmacol 2006 69: 727-736. Published online December 6, 2005; 10.1124/mol.105.017715 [Abstract] [Full Text] [PDF]  

Anders Wallqvist, John Connelly, Edward A. Sausville, David G. Covell, and Anne Monks

Differential Gene Expression as a Potential Classifier of 2-(4-Amino-3-methylphenyl)-5-fluorobenzothiazole-Sensitive and -Insensitive Cell Lines
Mol Pharmacol 2006 69: 737-748. Published online December 6, 2005; 10.1124/mol.105.017061 [Abstract] [Full Text] [PDF] [Data supplement]   

Cheng-Wei Yang, Wei-Liang Chen, Pei-Lin Wu, Huan-Yi Tseng, and Shiow-Ju Lee

Anti-Inflammatory Mechanisms of Phenanthroindolizidine Alkaloids
Mol Pharmacol 2006 69: 749-758. Published online December 6, 2005; 10.1124/mol.105.017764 [Abstract] [Full Text] [PDF]  

Michele L. Rankin, Paul S. Marinec, David M. Cabrera, Zheng Wang, Pedro A. Jose, and David R. Sibley

The D₁ Dopamine Receptor Is Constitutively Phosphorylated by G Protein-Coupled Receptor Kinase 4
Mol Pharmacol 2006 69: 759-769. Published online December 7, 2005; 10.1124/mol.105.019901 [Abstract] [Full Text] [PDF]  

Tami L. Thomae, Emily A. Stevens, Adam L. Liss, Norman R. Drinkwater, and Christopher A. Bradfield

The Teratogenic Sensitivity to 2,3,7,8-Tetrachlorodibenzo-p-dioxin Is Modified by a Locus on Mouse Chromosome 3
Mol Pharmacol 2006 69: 770-775. Published online December 14, 2005; 10.1124/mol.105.019760 [Abstract] [Full Text] [PDF]  

Amy L. Prasch, Robert L. Tanguay, Vatsal Mehta, Warren Heideman, and Richard E. Peterson

Identification of Zebrafish ARNT1 Homologs: 2,3,7,8-Tetrachlorodibenzo-p-dioxin Toxicity in the Developing Zebrafish Requires ARNT1
Mol Pharmacol 2006 69: 776-787. Published online November 23, 2005; 10.1124/mol.105.016873 [Abstract] [Full Text] [PDF]  

Sho-Ya Wang, Jane Mitchell, Denis B. Tikhonov, Boris S. Zhorov, and Ging Kuo Wang

How Batrachotoxin Modifies the Sodium Channel Permeation Pathway: Computer Modeling and Site-Directed Mutagenesis
Mol Pharmacol 2006 69: 788-795. Published online December 14, 2005; 10.1124/mol.105.018200 [Abstract] [Full Text] [PDF]  

Alison J. Tyson-Capper and G. Nicholas Europe-Finner

Novel Targeting of Cyclooxygenase-2 (COX-2) Pre-mRNA Using Antisense Morpholino Oligonucleotides Directed to the 3' Acceptor and 5' Donor Splice Sites of Exon 4: Suppression of COX-2 Activity in Human Amnion-Derived WISH and Myometrial Cells
Mol Pharmacol 2006 69: 796-804. Published online December 14, 2005; 10.1124/mol.105.020529 [Abstract] [Full Text] [PDF]  

Chiara Fiorentini, Maria Cristina Rizzetti, Chiara Busi, Sandra Bontempi, Ginetta Collo, PierFranco Spano, and Cristina Missale

Loss of Synaptic D1 Dopamine/N-Methyl-D-aspartate Glutamate Receptor Complexes in L-DOPA-Induced Dyskinesia in the Rat
Mol Pharmacol 2006 69: 805-812. Published online December 19, 2005; 10.1124/mol.105.016667 [Abstract] [Full Text] [PDF]  

Zhenglin Gu, Qian Jiang, Eunice Y. Yuen, and Zhen Yan

Activation of Dopamine D₄ Receptors Induces Synaptic Translocation of Ca²⁺/Calmodulin-Dependent Protein Kinase II in Cultured Prefrontal Cortical Neurons
Mol Pharmacol 2006 69: 813-822. Published online December 19, 2005; 10.1124/mol.105.018853 [Abstract] [Full Text] [PDF]  

Richard M. Brochu, Ivy E. Dick, Jason W. Tarpley, Erin McGowan, David Gunner, James Herrington, Pengcheng P. Shao, Dong Ok, Chunshi Li, William H. Parsons, Gary L. Stump, Christopher P. Regan, Joseph J. Lynch, Jr., Kathryn A. Lyons, Owen B. McManus, Samantha Clark, Zahid Ali, Gregory J. Kaczorowski, William J. Martin, and Birgit T. Priest

Block of Peripheral Nerve Sodium Channels Selectively Inhibits Features of Neuropathic Pain in Rats
Mol Pharmacol 2006 69: 823-832. Published online November 21, 2005; 10.1124/mol.105.018127 [Abstract] [Full Text] [PDF]  

Megan M. Kibbey, Mark J. Jameson, Erin M. Eaton, and Steven A. Rosenzweig

Insulin-Like Growth Factor Binding Protein-2: Contributions of the C-Terminal Domain to Insulin-Like Growth Factor-1 Binding
Mol Pharmacol 2006 69: 833-845. Published online November 23, 2005; 10.1124/mol.105.016998 [Abstract] [Full Text] [PDF]  

Chiung-Chun Huang and Kuei-Sen Hsu

Presynaptic Mechanism Underlying cAMP-Induced Synaptic Potentiation in Medial Prefrontal Cortex Pyramidal Neurons
Mol Pharmacol 2006 69: 846-856. Published online November 23, 2005; 10.1124/mol.105.018093 [Abstract] [Full Text] [PDF] [Data Supplement]   

Yiming Chen, Simone R. Green, Felicidad Almazan, and Oswald Quehenberger

The Amino Terminus and the Third Extracellular Loop of CX3CR1 Contain Determinants Critical for Distinct Receptor Functions
Mol Pharmacol 2006 69: 857-865. Published online November 29, 2005; 10.1124/mol.105.015909 [Abstract] [Full Text] [PDF] [Data Supplement]   

Zhao-Qiu Wu, Mu Li, Jie Chen, Zhi-Qiang Chi, and Jing-Gen Liu

Involvement of cAMP/cAMP-Dependent Protein Kinase Signaling Pathway in Regulation of Na⁺,K⁺-ATPase upon Activation of Opioid Receptors by Morphine
Mol Pharmacol 2006 69: 866-876. Published online November 29, 2005; 10.1124/mol.105.016501 [Abstract] [Full Text] [PDF]  

Chang-Seon Myung, William K. Lim, Joseph M. DeFilippo, Hiroshi Yasuda, Richard R. Neubig, and James C. Garrison

Regions in the G Protein Subunit Important for Interaction with Receptors and Effectors
Mol Pharmacol 2006 69: 877-887. Published online November 30, 2005; 10.1124/mol.105.018994 [Abstract] [Full Text] [PDF]  

Carlos P. Fitzsimons, Ursula A. Gompels, Dennis Verzijl, Henry F. Vischer, Claire Mattick, Rob Leurs, and Martine J. Smit

Chemokine-Directed Trafficking of Receptor Stimulus to Different G Proteins: Selective Inducible and Constitutive Signaling by Human Herpesvirus 6-Encoded Chemokine Receptor U51
Mol Pharmacol 2006 69: 888-898. Published online December 6, 2005; 10.1124/mol.105.015222 [Abstract] [Full Text] [PDF]  

Masahiro Ohtani, Takami Oka, Maryna Badyuk, Yingxian Xiao, Kenneth J. Kellar, and John W. Daly

Mouse -TC6 Insulinoma Cells: High Expression of Functional 34 Nicotinic Receptors Mediating Membrane Potential, Intracellular Calcium, and Insulin Release
Mol Pharmacol 2006 69: 899-907. Published online December 6, 2005; 10.1124/mol.105.014902 [Abstract] [Full Text] [PDF]  

Sarah Chouinard, Mélanie Tessier, Gabrielle Vernouillet, Sylvain Gauthier, Fernand Labrie, Olivier Barbier, and Alain Bélanger

Inactivation of the Pure Antiestrogen Fulvestrant and Other Synthetic Estrogen Molecules by UDP-Glucuronosyltransferase 1A Enzymes Expressed in Breast Tissue
Mol Pharmacol 2006 69: 908-920. Published online December 8, 2005; 10.1124/mol.105.015891 [Abstract] [Full Text] [PDF]  

J. A. M. Smith, S. M. Amagasu, J. Hembrador, S. Axt, R. Chang, T. Church, C. Gee, J. R. Jacobsen, T. Jenkins, E. Kaufman, N. Mai, and R. G. Vickery

Evidence for a Multivalent Interaction of Symmetrical, N-Linked, Lidocaine Dimers with Voltage-Gated Na⁺ Channels
Mol Pharmacol 2006 69: 921-931. Published online December 9, 2005; 10.1124/mol.105.019257 [Abstract] [Full Text] [PDF]  

Zhekang Ying, Liming Jin, Trenis Palmer, and R. Clinton Webb

Angiotensin II Up-Regulates the Leukemia-Associated Rho Guanine Nucleotide Exchange Factor (RhoGEF), a Regulator of G Protein Signaling Domain-Containing RhoGEF, in Vascular Smooth Muscle Cells
Mol Pharmacol 2006 69: 932-940. Published online December 14, 2005; 10.1124/mol.105.017830 [Abstract] [Full Text] [PDF]  

Jong Soon Kang, Yeo Dae Yoon, Mi Hwa Han, Sang-Bae Han, Kiho Lee, Ki Hoon Lee, Song-Kyu Park, and Hwan Mook Kim

Glabridin Suppresses Intercellular Adhesion Molecule-1 Expression in Tumor Necrosis Factor--Stimulated Human Umbilical Vein Endothelial Cells by Blocking Sphingosine Kinase Pathway: Implications of Akt, Extracellular Signal-Regulated Kinase, and Nuclear Factor-B/Rel Signaling Pathways
Mol Pharmacol 2006 69: 941-949. Published online December 14, 2005; 10.1124/mol.105.017442 [Abstract] [Full Text] [PDF] [Data Supplement]   

Chuen-Neu Wang, Hsien-Chia Pan, Yun-Lian Lin, Chih-Wen Chi, and Young-Ji Shiao

Ester Derivatives of Tournefolic Acid B Attenuate N-Methyl-D-aspartate-Mediated Excitotoxicity in Rat Cortical Neurons
Mol Pharmacol 2006 69: 950-959. Published online December 19, 2005; 10.1124/mol.105.018770 [Abstract] [Full Text] [PDF]  

Chun-Yu Wei, Kuo-Chin Huang, Yin-Hsiang Chou, Pe-Fang Hsieh, Kuei-Hui Lin, and Wan-Wan Lin

The Role of Rho-Associated Kinase in Differential Regulation by Statins of Interleukin-1- and Lipopolysaccharide-Mediated Nuclear Factor B Activation and Inducible Nitric-Oxide Synthase Gene Expression in Vascular Smooth Muscle Cells
Mol Pharmacol 2006 69: 960-967. Published online November 29, 2005; 10.1124/mol.105.017368 [Abstract] [Full Text] [PDF]  

Yan-Zhong Chang, Ya Ke, Jun-Rong Du, Georges M. Halpern, Kwok-Ping Ho, Li Zhu, Xiao-Song Gu, You-Jia Xu, Qin Wang, Lian-Zhi Li, Chen-Yuen Wang, and Zhong-Ming Qian

Increased Divalent Metal Transporter 1 Expression Might Be Associated with the Neurotoxicity of L-DOPA
Mol Pharmacol 2006 69: 968-974. Published online November 29, 2005; 10.1124/mol.105.017756 [Abstract] [Full Text] [PDF]  

Alexandra V. Andreeva, Rita Vaiskunaite, Mikhail A. Kutuzov, Jasmina Profirovic, Randal A. Skidgel, and Tatyana Voyno-Yasenetskaya

Novel Mechanisms of G Protein-Dependent Regulation of Endothelial Nitric-Oxide Synthase
Mol Pharmacol 2006 69: 975-982. Published online December 2, 2005; 10.1124/mol.105.018846 [Abstract] [Full Text] [PDF]  

Daniel Fernandes, José Eduardo da Silva-Santos, Danielle Duma, Christina Gaspar Villela, Christina Barja-Fidalgo, and Jamil Assreuy

Nitric Oxide-Dependent Reduction in Soluble Guanylate Cyclase Functionality Accounts for Early Lipopolysaccharide-Induced Changes in Vascular Reactivity
Mol Pharmacol 2006 69: 983-990. Published online December 2, 2005; 10.1124/mol.105.015479 [Abstract] [Full Text] [PDF]  

Nadia Hejazi, Chunyi Zhou, Murat Oz, Hui Sun, Jiang Hong Ye, and Li Zhang

⁹-Tetrahydrocannabinol and Endogenous Cannabinoid Anandamide Directly Potentiate the Function of Glycine Receptors
Mol Pharmacol 2006 69: 991-997. Published online December 6, 2005; 10.1124/mol.105.019174 [Abstract] [Full Text] [PDF]  

Jing Cao, Curtis L. Cetrulo, and Theoharis C. Theoharides

Corticotropin-Releasing Hormone Induces Vascular Endothelial Growth Factor Release from Human Mast Cells via the cAMP/Protein Kinase A/p38 Mitogen-Activated Protein Kinase Pathway
Mol Pharmacol 2006 69: 998-1006. Published online December 6, 2005; 10.1124/mol.105.019539 [Abstract] [Full Text] [PDF]  

Tal Soo Ha, Hyun-Ho Lim, Ga Eun Lee, Yong-Chul Kim, and Chul-Seung Park

Electrophysiological Characterization of Benzofuroindole-Induced Potentiation of Large-Conductance Ca²⁺-Activated K⁺ Channels
Mol Pharmacol 2006 69: 1007-1014. Published online December 6, 2005; 10.1124/mol.105.016170 [Abstract] [Full Text] [PDF]  

Erzsébet Lizanecz, Zsolt Bagi, Eniko T. Pásztor, Zoltán Papp, István Édes, Noémi Kedei, Peter M. Blumberg, and Attila Tóth

Phosphorylation-Dependent Desensitization by Anandamide of Vanilloid Receptor-1 (TRPV1) Function in Rat Skeletal Muscle Arterioles and in Chinese Hamster Ovary Cells Expressing TRPV1
Mol Pharmacol 2006 69: 1015-1023. Published online December 7, 2005; 10.1124/mol.105.015644 [Abstract] [Full Text] [PDF]  

Gábor Czirják and Péter Enyedi

Zinc and Mercuric Ions Distinguish TRESK from the Other Two-Pore-Domain K⁺ Channels
Mol Pharmacol 2006 69: 1024-1032. Published online December 14, 2005; 10.1124/mol.105.018556 [Abstract] [Full Text] [PDF]  

Catherine K. Andreadi, Lynne M. Howells, Paul A. Atherfold, and Margaret M. Manson

Involvement of Nrf2, p38, B-Raf, and Nuclear Factor-B, but Not Phosphatidylinositol 3-Kinase, in Induction of Hemeoxygenase-1 by Dietary Polyphenols
Mol Pharmacol 2006 69: 1033-1040. Published online December 14, 2005; 10.1124/mol.105.018374 [Abstract] [Full Text] [PDF]  

ChuHee Lee, Hyung-Kyu Lim, Joon Sakong, Yun-Sik Lee, Jae-Ryong Kim, and Suk-Hwan Baek

Janus Kinase-Signal Transducer and Activator of Transcription Mediates Phosphatidic Acid-Induced Interleukin (IL)-1 and IL-6 Production
Mol Pharmacol 2006 69: 1041-1047. Published online December 14, 2005; 10.1124/mol.105.018481 [Abstract] [Full Text] [PDF]  

Hong-Mei Zhang, Shao-Rui Chen, Minoru Matsui, Dinesh Gautam, Jürgen Wess, and Hui-Lin Pan

Opposing Functions of Spinal M₂, M₃, and M₄ Receptor Subtypes in Regulation of GABAergic Inputs to Dorsal Horn Neurons Revealed by Muscarinic Receptor Knockout Mice
Mol Pharmacol 2006 69: 1048-1055. Published online December 19, 2005; 10.1124/mol.105.018069 [Abstract] [Full Text] [PDF]  

Philip C. Burcham and Simon M. Pyke

Hydralazine Inhibits Rapid Acrolein-Induced Protein Oligomerization: Role of Aldehyde Scavenging and Adduct Trapping in Cross-Link Blocking and Cytoprotection
Mol Pharmacol 2006 69: 1056-1065. Published online December 20, 2005; 10.1124/mol.105.018168 [Abstract] [Full Text] [PDF]  

Kyoung Sun Park, Ha-Young Lee, Mi-Kyoung Kim, Eun Ha Shin, Seong Ho Jo, Sang Doo Kim, Dong-Soon Im, and Yoe-Sik Bae

Lysophosphatidylserine Stimulates L2071 Mouse Fibroblast Chemotactic Migration via a Process Involving Pertussis Toxin-Sensitive Trimeric G-Proteins
Mol Pharmacol 2006 69: 1066-1073. Published online December 20, 2005; 10.1124/mol.105.018960 [Abstract] [Full Text] [PDF]  

Retraction:

Notice of Retraction
Mol Pharmacol 2006 69: 1074. [Full Text] [PDF]  

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