Mol Pharm -- Table of Contents (71 [6])

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June 2007; 71 (6)   [Index by Author] [Cover Caption]

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       Accelerated Communication

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Minireview:

Maurizio Bifulco, Claudia Grimaldi, Patrizia Gazzerro, Simona Pisanti, and Antonietta Santoro: Rimonabant: Just an Antiobesity Drug? Current Evidence on Its Pleiotropic Effects
Mol Pharmacol 2007 71: 1445-1456. Published online February 27, 2007; 10.1124/mol.106.033118 [Abstract] [Full Text] [PDF]

Accelerated Communication:

Letizia Penolazzi, Margherita Zennaro, Elisabetta Lambertini, Elisa Tavanti, Elena Torreggiani, Roberto Gambari, and Roberta Piva: Induction of Estrogen Receptor ${alpha}$ Expression with Decoy Oligonucleotide Targeted to NFATc1 Binding Sites in Osteoblasts
Mol Pharmacol 2007 71: 1457-1462. Published online March 27, 2007; 10.1124/mol.107.034561 [Abstract] [Full Text] [PDF]

Articles:

Agnes Janoshazi, Maud Deraet, Jacques Callebert, Vincent Setola, Silke Guenther, Bruno Saubamea, Philippe Manivet, Jean-Marie Launay, and Luc Maroteaux: Modified Receptor Internalization upon Coexpression of 5-HT_1B Receptor and 5-HT_2B Receptors
Mol Pharmacol 2007 71: 1463-1474. Published online February 26, 2007; 10.1124/mol.106.032656 [Abstract] [Full Text] [PDF]

Wenyue Hu, Claudio Sorrentino, Michael S. Denison, Kyle Kolaja, and Mark R. Fielden: Induction of Cyp1a1 Is a Nonspecific Biomarker of Aryl Hydrocarbon Receptor Activation: Results of Large Scale Screening of Pharmaceuticals and Toxicants in Vivo and in Vitro
Mol Pharmacol 2007 71: 1475-1486. Published online February 27, 2007; 10.1124/mol.106.032748 [Abstract] [Full Text] [PDF] [Data Supplement]

Jun-ichi Asaka, Tomohiro Terada, Masahiro Tsuda, Toshiya Katsura, and Ken-ichi Inui: Identification of Essential Histidine and Cysteine Residues of the H⁺/Organic Cation Antiporter Multidrug and Toxin Extrusion (MATE)
Mol Pharmacol 2007 71: 1487-1493. Published online February 27, 2007; 10.1124/mol.106.032938 [Abstract] [Full Text] [PDF] [Data Supplement]

Ka Young Chung and Jeffery W. Walker: Interaction and Inhibitory Cross-Talk between Endothelin and ErbB Receptors in the Adult Heart
Mol Pharmacol 2007 71: 1494-1502. Published online March 1, 2007; 10.1124/mol.106.027599 [Abstract] [Full Text] [PDF] [Data Supplement]

Christian Lerche, Iva Bruhova, Holger Lerche, Klaus Steinmeyer, Aguan D. Wei, Nathalie Strutz-Seebohm, Florian Lang, Andreas E. Busch, Boris S. Zhorov, and Guiscard Seebohm: Chromanol 293B Binding in KCNQ1 (Kv7.1) Channels Involves Electrostatic Interactions with a Potassium Ion in the Selectivity Filter
Mol Pharmacol 2007 71: 1503-1511. Published online March 8, 2007; 10.1124/mol.106.031682 [Abstract] [Full Text] [PDF] [Erratum]

Ankur Kapur, Dow P. Hurst, Daniel Fleischer, Rob Whitnell, Ganesh A. Thakur, Alexandros Makriyannis, Patricia H. Reggio, and Mary E. Abood: Mutation Studies of Ser7.39 and Ser2.60 in the Human CB₁ Cannabinoid Receptor: Evidence for a Serine-Induced Bend in CB₁ Transmembrane Helix 7
Mol Pharmacol 2007 71: 1512-1524. Published online March 23, 2007; 10.1124/mol.107.034645 [Abstract] [Full Text] [PDF]

Corina Marx, Christina Yau, Surita Banwait, Yamei Zhou, Gary K. Scott, Byron Hann, John W. Park, and Christopher C. Benz: Proteasome-Regulated ERBB2 and Estrogen Receptor Pathways in Breast Cancer
Mol Pharmacol 2007 71: 1525-1534. Published online March 28, 2007; 10.1124/mol.107.034090 [Abstract] [Full Text] [PDF]

Mathias Soller, Stefan Dröse, Ulrich Brandt, Bernhard Brüne, and Andreas von Knethen: Mechanism of Thiazolidinedione-Dependent Cell Death in Jurkat T Cells
Mol Pharmacol 2007 71: 1535-1544. Published online February 26, 2007; 10.1124/mol.107.034371 [Abstract] [Full Text] [PDF]

Paqui G. Traves, Sonsoles Hortelano, Miriam Zeini, Ta-Hsiang Chao, Thanh Lam, Saskia T. Neuteboom, Emmanuel A. Theodorakis, Michael A. Palladino, Antonio Castrillo, and Lisardo Bosca: Selective Activation of Liver X Receptors by Acanthoic Acid-Related Diterpenes
Mol Pharmacol 2007 71: 1545-1553. Published online February 28, 2007; 10.1124/mol.106.031906 [Abstract] [Full Text] [PDF]

Ki Young Kim, Hyun Sill Cho, Won Hoon Jung, Sung Soo Kim, and Hyae Gyeong Cheon: Phosphatase and Tensin Homolog Deleted on Chromosome 10 Suppression Is an Important Process in Peroxisome Proliferator-Activated Receptor- ${gamma}$ Signaling in Adipocytes and Myotubes
Mol Pharmacol 2007 71: 1554-1562. Published online March 2, 2007; 10.1124/mol.106.031948 [Abstract] [Full Text] [PDF]

Outi Salminen, Jennifer A. Drapeau, J. Michael McIntosh, Allan C. Collins, Michael J. Marks, and Sharon R. Grady: Pharmacology of ${alpha}$ -Conotoxin MII-Sensitive Subtypes of Nicotinic Acetylcholine Receptors Isolated by Breeding of Null Mutant Mice
Mol Pharmacol 2007 71: 1563-1571. Published online March 6, 2007; 10.1124/mol.106.031492 [Abstract] [Full Text] [PDF]

Chris W. D. Jurgens, Hana M. Hammad, Jessica A. Lichter, Sarah J. Boese, Brian W. Nelson, Brianna L. Goldenstein, Kylie L. Davis, Ke Xu, Kristin L. Hillman, James E. Porter, and Van A. Doze: ${alpha}$ _2A Adrenergic Receptor Activation Inhibits Epileptiform Activity in the Rat Hippocampal CA3 Region
Mol Pharmacol 2007 71: 1572-1581. Published online March 6, 2007; 10.1124/mol.106.031773 [Abstract] [Full Text] [PDF]

Ping Li, John Bracamontes, Bryson W. Katona, Douglas F. Covey, Joe Henry Steinbach, and Gustav Akk: Natural and Enantiomeric Etiocholanolone Interact with Distinct Sites on the Rat ${alpha}$ 1 $beta$ 2 ${gamma}$ 2L GABA_A Receptor
Mol Pharmacol 2007 71: 1582-1590. Published online March 6, 2007; 10.1124/mol.106.033407 [Abstract] [Full Text] [PDF]

Lei Ci, Hiroyuki Kusuhara, Masashi Adachi, John D. Schuetz, Kenji Takeuchi, and Yuichi Sugiyama: Involvement of MRP4 (ABCC4) in the Luminal Efflux of Ceftizoxime and Cefazolin in the Kidney
Mol Pharmacol 2007 71: 1591-1597. Published online March 7, 2007; 10.1124/mol.106.031823 [Abstract] [Full Text] [PDF]

Akihiro Mouri, Yukihiro Noda, Akihiro Noda, Tomonobu Nakamura, Takanobu Tokura, Yoshimitsu Yura, Atsumi Nitta, Hiroshi Furukawa, and Toshitaka Nabeshima: Involvement of a Dysfunctional Dopamine-D1/N-Methyl-D-aspartate-NR1 and Ca²⁺/Calmodulin-Dependent Protein Kinase II Pathway in the Impairment of Latent Learning in a Model of Schizophrenia Induced by Phencyclidine
Mol Pharmacol 2007 71: 1598-1609. Published online March 7, 2007; 10.1124/mol.106.032961 [Abstract] [Full Text] [PDF] [Data Supplement]

Efrat Groner, Yacov Ashani, Donna Schorer-Apelbaum, Jeffrey Sterling, Yaacov Herzig, and Marta Weinstock: The Kinetics of Inhibition of Human Acetylcholinesterase and Butyrylcholinesterase by Two Series of Novel Carbamates
Mol Pharmacol 2007 71: 1610-1617. Published online March 8, 2007; 10.1124/mol.107.033928 [Abstract] [Full Text] [PDF]

Emma T. van der Westhuizen, Tim D. Werry, Patrick M. Sexton, and Roger J. Summers: The Relaxin Family Peptide Receptor 3 Activates Extracellular Signal-Regulated Kinase 1/2 through a Protein Kinase C-Dependent Mechanism
Mol Pharmacol 2007 71: 1618-1629. Published online March 9, 2007; 10.1124/mol.106.032763 [Abstract] [Full Text] [PDF]

Jeff D. Shadley, Karthika Divakaran, Kimber Munson, Ronald N. Hines, Kirk Douglas, and D. Gail McCarver: Identification and Functional Analysis of a Novel Human CYP2E1 Far Upstream Enhancer
Mol Pharmacol 2007 71: 1630-1639. Published online March 12, 2007; 10.1124/mol.106.031302 [Abstract] [Full Text] [PDF]

Shao-Chih Chiu and Ning-Sun Yang: Inhibition of Tumor Necrosis Factor- ${alpha}$ through Selective Blockade of Pre-mRNA Splicing by Shikonin
Mol Pharmacol 2007 71: 1640-1645. Published online March 14, 2007; 10.1124/mol.106.032821 [Abstract] [Full Text] [PDF]

Runping Wang, Xiaoli Zhang, Ningren Cui, Jianping Wu, Hailan Piao, Xueren Wang, Junda Su, and Chun Jiang: Subunit-Stoichiometric Evidence for Kir6.2 Channel Gating, ATP Binding, and Binding-Gating Coupling
Mol Pharmacol 2007 71: 1646-1656. Published online March 16, 2007; 10.1124/mol.106.030528 [Abstract] [Full Text] [PDF] [Data Supplement]

Hanna Harant, Barbara Wolff, Erwin P. Schreiner, Berndt Oberhauser, Lotte Hofer, Nicole Lettner, Sabine Maier, Jan E. de Vries, and Ivan J. Lindley: Inhibition of Vascular Endothelial Growth Factor Cotranslational Translocation by the Cyclopeptolide CAM741
Mol Pharmacol 2007 71: 1657-1665. Published online March 16, 2007; 10.1124/mol.107.034249 [Abstract] [Full Text] [PDF]

Emma L. Veale, Louise E. Kennard, Gemma L. Sutton, Georgina MacKenzie, Cristina Sandu, and Alistair Mathie: G ${alpha}$ _q-Mediated Regulation of TASK3 Two-Pore Domain Potassium Channels: The Role of Protein Kinase C
Mol Pharmacol 2007 71: 1666-1675. Published online March 20, 2007; 10.1124/mol.106.033241 [Abstract] [Full Text] [PDF]

Hyunchu Jeon, Heejung Kim, Daekyu Choi, Duksoo Kim, Shi-Young Park, Yung-Jin Kim, Young Mi Kim, and Yunjin Jung: Quercetin Activates an Angiogenic Pathway, Hypoxia Inducible Factor (HIF)-1-Vascular Endothelial Growth Factor, by Inhibiting HIF-Prolyl Hydroxylase: a Structural Analysis of Quercetin for Inhibiting HIF-Prolyl Hydroxylase
Mol Pharmacol 2007 71: 1676-1684. Published online March 21, 2007; 10.1124/mol.107.034041 [Abstract] [Full Text] [PDF] [Data Supplement]

Matthieu Raoux, Cécile Colomban, Patrick Delmas, and Marcel Crest: The Amine-Containing Cutaneous Irritant Heptylamine Inhibits the Volume-Regulated Anion Channel and Mobilizes Intracellular Calcium in Normal Human Epidermal Keratinocytes
Mol Pharmacol 2007 71: 1685-1694. Published online March 23, 2007; 10.1124/mol.106.033324 [Abstract] [Full Text] [PDF]

Sangeeta Ghosh, Nishant Patel, Douglas Rahn, Jenna McAllister, Sina Sadeghi, Geoffrey Horwitz, Diana Berry, Kai Xuan Wang, and Russell H. Swerdlow: The Thiazolidinedione Pioglitazone Alters Mitochondrial Function in Human Neuron-Like Cells
Mol Pharmacol 2007 71: 1695-1702. Published online March 26, 2007; 10.1124/mol.106.033845 [Abstract] [Full Text] [PDF]

Bokyung Sung, Manoj K. Pandey, and Bharat B. Aggarwal: Fisetin, an Inhibitor of Cyclin-Dependent Kinase 6, Down-Regulates Nuclear Factor- ${kappa}$ B-Regulated Cell Proliferation, Antiapoptotic and Metastatic Gene Products through the Suppression of TAK-1 and Receptor-Interacting Protein-Regulated I ${kappa}$ B ${alpha}$ Kinase Activation
Mol Pharmacol 2007 71: 1703-1714. Published online March 26, 2007; 10.1124/mol.107.034512 [Abstract] [Full Text] [PDF]

Saswati Hazra, Raj K. Batra, Hsin H. Tai, Sherven Sharma, Xiaoyan Cui, and Steven M. Dubinett: Pioglitazone and Rosiglitazone Decrease Prostaglandin E₂ in Non–Small-Cell Lung Cancer Cells by Up-Regulating 15-Hydroxyprostaglandin Dehydrogenase
Mol Pharmacol 2007 71: 1715-1720. Published online April 5, 2007; 10.1124/mol.106.033357 [Abstract] [Full Text] [PDF]

Cover Caption:

About the cover: Results obtained from CM studies of WT CB₁ TMH7 (green) and the CB₁ S7.39(383)A mutant TMH7 (magenta). Please see the article by Kapur et al. on page 1512 of this issue.