Minireview:

John S. Lazo, Linda S. Brady, and Ray Dingledine

Building a Pharmacological Lexicon: Small Molecule Discovery in Academia
Mol Pharmacol 2007 72: 1-7. Published online April 3, 2007; 10.1124/mol.107.035113 [Abstract] [Full Text] [PDF]  

Articles:

Beate Niesler, Jutta Walstab, Sandra Combrink, Dorothee Möller, Johannes Kapeller, Jens Rietdorf, Heinz Bönisch, Manfred Göthert, Gudrun Rappold, and Michael Brüss

Characterization of the Novel Human Serotonin Receptor Subunits 5-HT_3C,5-HT_3D, and 5-HT_3E
Mol Pharmacol 2007 72: 8-17. Published online March 28, 2007; 10.1124/mol.106.032144 [Abstract] [Full Text] [PDF] [Data Supplement]   

Changhua Ji, Jun Zhang, Marianna Dioszegi, Sophie Chiu, Eileen Rao, Andre deRosier, Nick Cammack, Michael Brandt, and Surya Sankuratri

CCR5 Small-Molecule Antagonists and Monoclonal Antibodies Exert Potent Synergistic Antiviral Effects by Cobinding to the Receptor
Mol Pharmacol 2007 72: 18-28. Published online March 28, 2007; 10.1124/mol.107.035055 [Abstract] [Full Text] [PDF]  

Hiroshi Aoki, Yasunari Takada, Seiji Kondo, Raymond Sawaya, Bharat B. Aggarwal, and Yasuko Kondo

Evidence That Curcumin Suppresses the Growth of Malignant Gliomas in Vitro and in Vivo through Induction of Autophagy: Role of Akt and Extracellular Signal-Regulated Kinase Signaling Pathways
Mol Pharmacol 2007 72: 29-39. Published online March 29, 2007; 10.1124/mol.106.033167 [Abstract] [Full Text] [PDF] [Data Supplement]   

Paul Chen, Zhenglin Gu, Wenhua Liu, and Zhen Yan

Glycogen Synthase Kinase 3 Regulates N-Methyl-D-aspartate Receptor Channel Trafficking and Function in Cortical Neurons
Mol Pharmacol 2007 72: 40-51. Published online March 30, 2007; 10.1124/mol.107.034942 [Abstract] [Full Text] [PDF]  

Tanuja Bordia, Sharon R. Grady, J. Michael McIntosh, and Maryka Quik

Nigrostriatal Damage Preferentially Decreases a Subpopulation of 62^* nAChRs in Mouse, Monkey, and Parkinson's Disease Striatum
Mol Pharmacol 2007 72: 52-61. Published online April 4, 2007; 10.1124/mol.107.035998 [Abstract] [Full Text] [PDF]  

Eun Ju Kim, Seung-Nam Jung, Kun Ho Son, Sung Ran Kim, Tae Youl Ha, Myoung Gyu Park, In Gun Jo, Jong Guk Park, Wonchae Choe, Sung-Soo Kim, and Joohun Ha

Antidiabetes and Antiobesity Effect of Cryptotanshinone via Activation of AMP-Activated Protein Kinase
Mol Pharmacol 2007 72: 62-72. Published online April 11, 2007; 10.1124/mol.107.034447 [Abstract] [Full Text] [PDF]  

Yan Xie, Dennis W. Wolff, Ming-Fong Lin, and Yaping Tu

Vasoactive Intestinal Peptide Transactivates the Androgen Receptor through a Protein Kinase A-Dependent Extracellular Signal-Regulated Kinase Pathway in Prostate Cancer LNCaP Cells
Mol Pharmacol 2007 72: 73-85. Published online April 12, 2007; 10.1124/mol.107.033894 [Abstract] [Full Text] [PDF]  

Buranee Yangthara, Aaron Mills, Varanuj Chatsudthipong, Lukmanee Tradtrantip, and A. S. Verkman

Small-Molecule Vasopressin-2 Receptor Antagonist Identified by a G-Protein Coupled Receptor "Pathway" Screen
Mol Pharmacol 2007 72: 86-94. Published online April 13, 2007; 10.1124/mol.107.034496 [Abstract] [Full Text] [PDF]  

Mei Qiang, Ashley D. Denny, and Maharaj K. Ticku

Chronic Intermittent Ethanol Treatment Selectively Alters N-Methyl-D-aspartate Receptor Subunit Surface Expression in Cultured Cortical Neurons
Mol Pharmacol 2007 72: 95-102. Published online April 17, 2007; 10.1124/mol.106.033043 [Abstract] [Full Text] [PDF]  

Mina Ushiyama, Ryuji Ikeda, Hideki Sugawara, Morikatsu Yoshida, Kenji Mori, Kenji Kangawa, Kazuhiko Inoue, Katsushi Yamada, and Atsuro Miyata

Differential Intracellular Signaling through PAC1 Isoforms as a Result of Alternative Splicing in the First Extracellular Domain and the Third Intracellular Loop
Mol Pharmacol 2007 72: 103-111. Published online April 18, 2007; 10.1124/mol.107.035477 [Abstract] [Full Text] [PDF]  

Yong Xu and Teresa L. Krukoff

Adrenomedullin Stimulates Nitric Oxide Production from Primary Rat Hypothalamic Neurons: Roles of Calcium and Phosphatases
Mol Pharmacol 2007 72: 112-120. Published online April 19, 2007; 10.1124/mol.106.033761 [Abstract] [Full Text] [PDF]  

Sigridur A. Ásgeirsdóttir, Jan A. A. M. Kamps, Hester I. Bakker, Peter J. Zwiers, Peter Heeringa, Karen van der Weide, Harry van Goor, Arjen H. Petersen, Henriëtte Morselt, Henk E. Moorlag, E. Steenbergen, Cees G. Kallenberg, and Grietje Molema

Site-Specific Inhibition of Glomerulonephritis Progression by Targeted Delivery of Dexamethasone to Glomerular Endothelium
Mol Pharmacol 2007 72: 121-131. Published online April 23, 2007; 10.1124/mol.107.034140 [Abstract] [Full Text] [PDF]  

Susan L. Mooberry, Kimberly N. Weiderhold, Sivanesan Dakshanamurthy, Ernest Hamel, Edith J. Banner, Anastasia Kharlamova, Jonathan Hempel, John T. Gupton, and Milton L. Brown

Identification and Characterization of a New Tubulin-Binding Tetrasubstituted Brominated Pyrrole
Mol Pharmacol 2007 72: 132-140. Published online April 24, 2007; 10.1124/mol.107.034876 [Abstract] [Full Text] [PDF]  

Martin Gamerdinger, Angela B. Clement, and Christian Behl

Cholesterol-Like Effects of Selective Cyclooxygenase Inhibitors and Fibrates on Cellular Membranes and Amyloid- Production
Mol Pharmacol 2007 72: 141-151. Published online March 29, 2007; 10.1124/mol.107.034009 [Abstract] [Full Text] [PDF] [Data Supplement]   

Nicholas J. Gaspar, Lingyun Li, Ann M. Kapoun, Satyanarayana Medicherla, Mamatha Reddy, Georgia Li, Gilbert O'Young, Diana Quon, Margaret Henson, Deborah L. Damm, Gladys T. Muiru, Alison Murphy, Linda S. Higgins, Sarvajit Chakravarty, and Darren H. Wong

Inhibition of Transforming Growth Factor Signaling Reduces Pancreatic Adenocarcinoma Growth and Invasiveness
Mol Pharmacol 2007 72: 152-161. Published online March 30, 2007; 10.1124/mol.106.029025 [Abstract] [Full Text] [PDF] [Data Supplement]   

Stefania Merighi, Annalisa Benini, Prisco Mirandola, Stefania Gessi, Katia Varani, Edward Leung, Stephen Maclennan, Pier Giovanni Baraldi, and Pier Andrea Borea

Hypoxia Inhibits Paclitaxel-Induced Apoptosis through Adenosine-Mediated Phosphorylation of Bad in Glioblastoma Cells
Mol Pharmacol 2007 72: 162-172. Published online March 30, 2007; 10.1124/mol.106.031849 [Abstract] [Full Text] [PDF]  

Takashi Ito, Koko Asakura, Katsuhiko Tougou, Tsuyoshi Fukuda, Ryuji Kubota, Shinpei Nonen, Yasushi Fujio, and Junichi Azuma

Regulation of Cytochrome P450 2E1 under Hypertonic Environment through TonEBP in Human Hepatocytes
Mol Pharmacol 2007 72: 173-181. Published online April 17, 2007; 10.1124/mol.106.033480 [Abstract] [Full Text] [PDF]  

Stéphane S. Martin, Brian J. Holleran, Emanuel Escher, Gaétan Guillemette, and Richard Leduc

Activation of the Angiotensin II Type 1 Receptor Leads to Movement of the Sixth Transmembrane Domain: Analysis by the Substituted Cysteine Accessibility Method
Mol Pharmacol 2007 72: 182-190. Published online April 19, 2007; 10.1124/mol.106.033670 [Abstract] [Full Text] [PDF]  

Alexander Kollau, Matteo Beretta, Antonius C. F. Gorren, Michael Russwurm, Doris Koesling, Kurt Schmidt, and Bernd Mayer

Bioactivation of Nitroglycerin by Ascorbate
Mol Pharmacol 2007 72: 191-196. Published online April 19, 2007; 10.1124/mol.107.035642 [Abstract] [Full Text] [PDF]  

Nicoletta Pedemonte, Davide Boido, Oscar Moran, Michele Giampieri, Mauro Mazzei, Roberto Ravazzolo, and Luis J. V. Galietta

Structure-Activity Relationship of 1,4-Dihydropyridines as Potentiators of the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel
Mol Pharmacol 2007 72: 197-207. Published online April 23, 2007; 10.1124/mol.107.034702 [Abstract] [Full Text] [PDF] [Data Supplement]   

Pan-Yue Deng, Shree Kanta S. Poudel, Lalida Rojanathammanee, James E. Porter, and Saobo Lei

Serotonin Inhibits Neuronal Excitability by Activating Two-Pore Domain K⁺ Channels in the Entorhinal Cortex
Mol Pharmacol 2007 72: 208-218. Published online April 23, 2007; 10.1124/mol.107.034389 [Abstract] [Full Text] [PDF]  

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