Mol Pharm -- Table of Contents (73 [1])

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January 2008; 73 (1) [Index by Author] [Cover Caption]

Articles

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Table of Contents (PDF) | Editorial Board (PDF) | Front Matter (PDF) | Back Matter (PDF) |

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Articles:

Steven Gu, Annepa Anton, Samina Salim, Kendall J. Blumer, Carmen W. Dessauer, and Scott P. Heximer: Alternative Translation Initiation of Human Regulators of G-Protein Signaling-2 Yields a Set of Functionally Distinct Proteins
Mol Pharmacol 2008 73: 1-11. Published online September 27, 2007; 10.1124/mol.107.036285 [Abstract] [Full Text] [PDF] [Data Supplement]

Saroj Velamakanni, Tavan Janvilisri, Sanjay Shahi, and Hendrik W. van Veen: A Functional Steroid-Binding Element in an ATP-Binding Cassette Multidrug Transporter
Mol Pharmacol 2008 73: 12-17. Published online October 5, 2007; 10.1124/mol.107.038299 [Abstract] [Full Text] [PDF] [Erratum]

Travis J. Jerde, William S. Mellon, Dale E. Bjorling, Celina M. Checura, Kwadwo Owusu-Ofori, John J. Parrish, and Stephen Y. Nakada: Stretch Induction of Cyclooxygenase-2 Expression in Human Urothelial Cells Is Calcium- and Protein Kinase C ${zeta}$ -Dependent
Mol Pharmacol 2008 73: 18-26. Published online October 9, 2007; 10.1124/mol.107.035519 [Abstract] [Full Text] [PDF] [Erratum]

Ryan M. Drenan, Raad Nashmi, Princess Imoukhuede, Herwig Just, Sheri McKinney, and Henry A. Lester: Subcellular Trafficking, Pentameric Assembly, and Subunit Stoichiometry of Neuronal Nicotinic Acetylcholine Receptors Containing Fluorescently Labeled ${alpha}$ 6 and β3 Subunits
Mol Pharmacol 2008 73: 27-41. Published online October 11, 2007; 10.1124/mol.107.039180 [Abstract] [Full Text] [PDF] [Data Supplement]

Michael Dattilo, Nicholas J. Penington, and Keith Williams: Inhibition of TRPC5 Channels by Intracellular ATP
Mol Pharmacol 2008 73: 42-49. Published online October 9, 2007; 10.1124/mol.107.040899 [Abstract] [Full Text] [PDF] [Data Supplement]

Dmitry Gorbunov, Valentin Gorboulev, Natalia Shatskaya, Thomas Mueller, Ernst Bamberg, Thomas Friedrich, and Hermann Koepsell: High-Affinity Cation Binding to Organic Cation Transporter 1 Induces Movement of Helix 11 and Blocks Transport after Mutations in a Modeled Interaction Domain between Two Helices
Mol Pharmacol 2008 73: 50-61. Published online October 16, 2007; 10.1124/mol.107.040170 [Abstract] [Full Text] [PDF]

Monica Einstein, Taro E. Akiyama, Gino A. Castriota, Chuanlin F. Wang, Brian McKeever, Ralph T. Mosley, Joseph W. Becker, David E. Moller, Peter T. Meinke, Harold B. Wood, and Joel P. Berger: The Differential Interactions of Peroxisome Proliferator-Activated Receptor ${gamma}$ Ligands with Tyr473 Is a Physical Basis for Their Unique Biological Activities
Mol Pharmacol 2008 73: 62-74. Published online October 16, 2007; 10.1124/mol.107.041202 [Abstract] [Full Text] [PDF]

Alan J. Stewart, Robin Sellar, Donald J. Wilson, Robert P. Millar, and Zhi-Liang Lu: Identification of a Novel Ligand Binding Residue Arg^38(1.35) in the Human Gonadotropin-Releasing Hormone Receptor
Mol Pharmacol 2008 73: 75-81. Published online October 17, 2007; 10.1124/mol.107.040816 [Abstract] [Full Text] [PDF]

Darrell R. Boverhof, Lyle D. Burgoon, Kurt J. Williams, and Timothy R. Zacharewski: Inhibition of Estrogen-Mediated Uterine Gene Expression Responses by Dioxin
Mol Pharmacol 2008 73: 82-93. Published online October 17, 2007; 10.1124/mol.107.040451 [Abstract] [Full Text] [PDF] [Data Supplement]

Remko A. Bakker, Aldo Jongejan, Kamonchanok Sansuk, Uli Hacksell, Henk Timmerman, Mark R. Brann, Dave M. Weiner, Leonardo Pardo, and Rob Leurs: Constitutively Active Mutants of the Histamine H₁ Receptor Suggest a Conserved Hydrophobic Asparagine-Cage That Constrains the Activation of Class A G Protein-Coupled Receptors
Mol Pharmacol 2008 73: 94-103. Published online October 24, 2007; 10.1124/mol.107.038547 [Abstract] [Full Text] [PDF]

Huanchen Wang, Mengchun Ye, Howard Robinson, Sharron H. Francis, and Hengming Ke: Conformational Variations of Both Phosphodiesterase-5 and Inhibitors Provide the Structural Basis for the Physiological Effects of Vardenafil and Sildenafil
Mol Pharmacol 2008 73: 104-110. Published online October 24, 2007; 10.1124/mol.107.040212 [Abstract] [Full Text] [PDF]

Wei Xu, Chih-Ling Chou, Haipeng Sun, Hiromichi Fujino, Qin M. Chen, and John W. Regan: FP Prostanoid Receptor-Mediated Induction of the Expression of Early Growth Response Factor-1 by Activation of a Ras/Raf/Mitogen-Activated Protein Kinase Signaling Cascade
Mol Pharmacol 2008 73: 111-118. Published online October 2, 2007; 10.1124/mol.107.038778 [Abstract] [Full Text] [PDF]

Liying Wang, Pithi Chanvorachote, David Toledo, Christian Stehlik, Robert R. Mercer, Vincent Castranova, and Yon Rojanasakul: Peroxide Is a Key Mediator of Bcl-2 Down-Regulation and Apoptosis Induction by Cisplatin in Human Lung Cancer Cells
Mol Pharmacol 2008 73: 119-127. Published online October 2, 2007; 10.1124/mol.107.040873 [Abstract] [Full Text] [PDF]

Sergey N. Kolomeichuk, Anca Bene, Meenakshi Upreti, Richard A. Dennis, Christopher S. Lyle, Maheswari Rajasekaran, and Timothy C. Chambers: Induction of Apoptosis by Vinblastine via c-Jun Autoamplification and p53-Independent Down-Regulation of p21^WAF1/CIP1
Mol Pharmacol 2008 73: 128-136. Published online October 4, 2007; 10.1124/mol.107.039750 [Abstract] [Full Text] [PDF] [Erratum] [Data Supplement]

Jun Gao, Leah A. Mitchell, Fredine T. Lauer, and Scott W. Burchiel: p53 and ATM/ATR Regulate 7,12-Dimethylbenz[a]anthracene-Induced Immunosuppression
Mol Pharmacol 2008 73: 137-146. Published online October 9, 2007; 10.1124/mol.107.039230 [Abstract] [Full Text] [PDF]

Sylvie Desmarais, W. Cameron Black, Renata Oballa, Sonia Lamontagne, Denis Riendeau, Paul Tawa, Le Thi Duong, Maureen Pickarski, and M. David Percival: Effect of Cathepsin K Inhibitor Basicity on in Vivo Off-Target Activities
Mol Pharmacol 2008 73: 147-156. Published online October 16, 2007; 10.1124/mol.107.039511 [Abstract] [Full Text] [PDF] [Data Supplement]

Adam C. Errington, Thomas Stöhr, Cara Heers, and George Lees: The Investigational Anticonvulsant Lacosamide Selectively Enhances Slow Inactivation of Voltage-Gated Sodium Channels
Mol Pharmacol 2008 73: 157-169. Published online October 16, 2007; 10.1124/mol.107.039867 [Abstract] [Full Text] [PDF]

Wei-Lan Yeh, Chun-Jung Lin, and Wen-Mei Fu: Enhancement of Glucose Transporter Expression of Brain Endothelial Cells by Vascular Endothelial Growth Factor Derived from Glioma Exposed to Hypoxia
Mol Pharmacol 2008 73: 170-177. Published online October 17, 2007; 10.1124/mol.107.038851 [Abstract] [Full Text] [PDF]

Hui Zheng, Horace H. Loh, and Ping-Yee Law: β-Arrestin-Dependent µ-Opioid Receptor-Activated Extracellular Signal-Regulated Kinases (ERKs) Translocate to Nucleus in Contrast to G Protein-Dependent ERK Activation
Mol Pharmacol 2008 73: 178-190. Published online October 18, 2007; 10.1124/mol.107.039842 [Abstract] [Full Text] [PDF]

Alessandra Pattarozzi, Monica Gatti, Federica Barbieri, Roberto Würth, Carola Porcile, Gianluigi Lunardi, Alessandra Ratto, Roberto Favoni, Adriana Bajetto, Angelo Ferrari, and Tullio Florio: 17β-Estradiol Promotes Breast Cancer Cell Proliferation-Inducing Stromal Cell-Derived Factor-1-Mediated Epidermal Growth Factor Receptor Transactivation: Reversal by Gefitinib Pretreatment
Mol Pharmacol 2008 73: 191-202. Published online October 24, 2007; 10.1124/mol.107.039974 [Abstract] [Full Text] [PDF]

Manminder Kaur, Joanna E. Chivers, Mark A. Giembycz, and Robert Newton: Long-Acting β₂-Adrenoceptor Agonists Synergistically Enhance Glucocorticoid-Dependent Transcription in Human Airway Epithelial and Smooth Muscle Cells
Mol Pharmacol 2008 73: 203-214. Published online September 27, 2007; 10.1124/mol.107.040121 [Abstract] [Full Text] [PDF] [Data Supplement]

Luxia Zu, Hongfeng Jiang, Jinhan He, Chong Xu, Shenshen Pu, Meifang Liu, and Guoheng Xu: Salicylate Blocks Lipolytic Actions of Tumor Necrosis Factor- ${alpha}$ in Primary Rat Adipocytes
Mol Pharmacol 2008 73: 215-223. Published online October 2, 2007; 10.1124/mol.107.039479 [Abstract] [Full Text] [PDF]

R. Karoly, A. Mike, P. Illes, and Z. Gerevich: The Unusual State-Dependent Affinity of P2X₃ Receptors Can Be Explained by an Allosteric Two-Open-State Model
Mol Pharmacol 2008 73: 224-234. Published online October 9, 2007; 10.1124/mol.107.038901 [Abstract] [Full Text] [PDF]

Clarissa S. Craft, Li Xu, Diana Romero, Calvin P. H. Vary, and Raymond C. Bergan: Genistein Induces Phenotypic Reversion of Endoglin Deficiency in Human Prostate Cancer Cells
Mol Pharmacol 2008 73: 235-242. Published online October 19, 2007; 10.1124/mol.107.038935 [Abstract] [Full Text] [PDF]

Z. Ping Lin, Yong-Lian Zhu, Dennis R. Johnson, Kevin P. Rice, Timothy Nottoli, Bryan C. Hains, James McGrath, Stephen G. Waxman, and Alan C. Sartorelli: Disruption of cAMP and Prostaglandin E₂ Transport by Multidrug Resistance Protein 4 Deficiency Alters cAMP-Mediated Signaling and Nociceptive Response
Mol Pharmacol 2008 73: 243-251. Published online October 24, 2007; 10.1124/mol.107.039594 [Abstract] [Full Text] [PDF]

Xing Liu, Annmarie Surprenant, Hong-Ju Mao, Sebastien Roger, Rong Xia, Helen Bradley, and Lin-Hua Jiang: Identification of Key Residues Coordinating Functional Inhibition of P2X₇ Receptors by Zinc and Copper
Mol Pharmacol 2008 73: 252-259. Published online October 24, 2007; 10.1124/mol.107.039651 [Abstract] [Full Text] [PDF] [Data Supplement]

Natalia Krynetskaia, Hongbo Xie, Slobodan Vucetic, Zoran Obradovic, and Evgeny Krynetskiy: High Mobility Group Protein B1 Is an Activator of Apoptotic Response to Antimetabolite Drugs
Mol Pharmacol 2008 73: 260-269. Published online October 19, 2007; 10.1124/mol.107.041764 [Abstract] [Full Text] [PDF] [Data Supplement]

Cover Caption:

About the cover: SPPARγM2 interacts with different residues within the hPPARγLBD than rosiglitazone. See the article by Einstein et al. on page 62 of this issue.