Mol Pharm -- Table of Contents (75 [5])

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May 2009; 75 (5)   [Index by Author] [Cover Caption]

       Accelerated Communications

       Articles

       Errata

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Table of Contents (PDF) | Editorial Board (PDF) | Front Matter (PDF) | Back Matter (PDF) |

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

Accelerated Communications:

Joshua G. DeKeyser, Michael C. Stagliano, Scott S. Auerbach, K. Sandeep Prabhu, A. Daniel Jones, and Curtis J. Omiecinski: Di(2-ethylhexyl) phthalate Is a Highly Potent Agonist for the Human Constitutive Androstane Receptor Splice Variant CAR2
Mol Pharmacol 2009 75: 1005-1013. Published online February 11, 2009; 10.1124/mol.108.053702 [Abstract] [Full Text] [PDF]

S. Chiechio, M. Zammataro, M. E. Morales, C. L. Busceti, F. Drago, R. W. Gereau, IV, A. Copani, and F. Nicoletti: Epigenetic Modulation of mGlu2 Receptors by Histone Deacetylase Inhibitors in the Treatment of Inflammatory Pain
Mol Pharmacol 2009 75: 1014-1020. Published online March 2, 2009; 10.1124/mol.108.054346 [Abstract] [Full Text] [PDF]

Articles:

Hee Jung Kim and Stanley A. Thayer: Lithium Increases Synapse Formation between Hippocampal Neurons by Depleting Phosphoinositides
Mol Pharmacol 2009 75: 1021-1030. Published online February 2, 2009; 10.1124/mol.108.052357 [Abstract] [Full Text] [PDF] [Data Supplement]

Eikichi Ihara, Paul L. Beck, Mona Chappellaz, Josee Wong, Shaun A. Medlicott, and Justin A. MacDonald: Mitogen-Activated Protein Kinase Pathways Contribute to Hypercontractility and Increased Ca²⁺ Sensitization in Murine Experimental Colitis
Mol Pharmacol 2009 75: 1031-1041. Published online February 3, 2009; 10.1124/mol.108.049858 [Abstract] [Full Text] [PDF] [Data Supplement]

Ren-Shiang Chen and Philip M. Best: A Small Peptide Inhibitor of the Low Voltage-Activated Calcium Channel Cav3.1
Mol Pharmacol 2009 75: 1042-1051. Published online February 4, 2009; 10.1124/mol.108.052654 [Abstract] [Full Text] [PDF]

Françoise Chiche, Morwenna Le Guillou, Gérard Chétrite, Françoise Lasnier, Isabelle Dugail, Christian Carpéné, Marthe Moldes, and Bruno Fève: Antidepressant Phenelzine Alters Differentiation of Cultured Human and Mouse Preadipocytes
Mol Pharmacol 2009 75: 1052-1061. Published online February 6, 2009; 10.1124/mol.108.052563 [Abstract] [Full Text] [PDF] [Data Supplement]

Eleanor Peacey, Christopher C. J. Miller, John Dunlop, and Marcus Rattray: The Four Major N- and C-Terminal Splice Variants of the Excitatory Amino Acid Transporter GLT-1 Form Cell Surface Homomeric and Heteromeric Assemblies
Mol Pharmacol 2009 75: 1062-1073. Published online February 6, 2009; 10.1124/mol.108.052829 [Abstract] [Full Text] [PDF] [Data Supplement]

Jean-Marc Navenot, Nobutaka Fujii, and Stephen C. Peiper: KiSS1 Metastasis Suppressor Gene Product Induces Suppression of Tyrosine Kinase Receptor Signaling to Akt, Tumor Necrosis Factor Family Ligand Expression, and Apoptosis
Mol Pharmacol 2009 75: 1074-1083. Published online February 6, 2009; 10.1124/mol.108.054270 [Abstract] [Full Text] [PDF] [Data Supplement]

David C. Chiara, Filbert H. Hong, Enrique Arevalo, S. Shaukat Husain, Keith W. Miller, Stuart A. Forman, and Jonathan B. Cohen: Time-Resolved Photolabeling of the Nicotinic Acetylcholine Receptor by [³H]Azietomidate, an Open-State Inhibitor
Mol Pharmacol 2009 75: 1084-1095. Published online February 13, 2009; 10.1124/mol.108.054353 [Abstract] [Full Text] [PDF]

Anne-Marie L. Fay, Christopher R. Corbeil, Patricia Brown, Nicolas Moitessier, and Derek Bowie: Functional Characterization and In Silico Docking of Full and Partial GluK2 Kainate Receptor Agonists
Mol Pharmacol 2009 75: 1096-1107. Published online February 18, 2009; 10.1124/mol.108.054254 [Abstract] [Full Text] [PDF]

Thomas Moore-Morris, Annie Varrault, Matteo E. Mangoni, Anne Le Digarcher, Vincent Negre, Christelle Dantec, Laurent Journot, Joel Nargeot, and Brigitte Couette: Identification of Potential Pharmacological Targets by Analysis of the Comprehensive G Protein-Coupled Receptor Repertoire in the Four Cardiac Chambers
Mol Pharmacol 2009 75: 1108-1116. Published online February 19, 2009; 10.1124/mol.108.054155 [Abstract] [Full Text] [PDF] [Data Supplement]

Paiboon Jungsuwadee, Ramaneeya Nithipongvanitch, Yumin Chen, Terry D. Oberley, D. Allan Butterfield, Daret K. St. Clair, and Mary Vore: Mrp1 Localization and Function in Cardiac Mitochondria after Doxorubicin
Mol Pharmacol 2009 75: 1117-1126. Published online February 20, 2009; 10.1124/mol.108.052209 [Abstract] [Full Text] [PDF]

Jan Balzarini, Ineke Van Daele, Ana Negri, Nicola Solaroli, Anna Karlsson, Sandra Liekens, Federico Gago, and Serge Van Calenbergh: Human Mitochondrial Thymidine Kinase Is Selectively Inhibited by 3'-Thiourea Derivatives of β-Thymidine: Identification of Residues Crucial for Both Inhibition and Catalytic Activity
Mol Pharmacol 2009 75: 1127-1136. Published online February 20, 2009; 10.1124/mol.108.053785 [Abstract] [Full Text] [PDF]

Cagdas D. Son, Fraser J. Moss, Bruce N. Cohen, and Henry A. Lester: Nicotine Normalizes Intracellular Subunit Stoichiometry of Nicotinic Receptors Carrying Mutations Linked to Autosomal Dominant Nocturnal Frontal Lobe Epilepsy
Mol Pharmacol 2009 75: 1137-1148. Published online February 23, 2009; 10.1124/mol.108.054494 [Abstract] [Full Text] [PDF] [Data Supplement]

Eran E. Bram, Yamit Adar, Nufar Mesika, Michal Sabisz, Andrzej Skladanowski, and Yehuda G. Assaraf: Structural Determinants of Imidazoacridinones Facilitating Antitumor Activity Are Crucial for Substrate Recognition by ABCG2
Mol Pharmacol 2009 75: 1149-1159. Published online February 27, 2009; 10.1124/mol.109.054791 [Abstract] [Full Text] [PDF]

Ralf Gilsbach, Christoph Röser, Nadine Beetz, Marc Brede, Kerstin Hadamek, Miriam Haubold, Jost Leemhuis, Melanie Philipp, Johanna Schneider, Michal Urbanski, Bela Szabo, David Weinshenker, and Lutz Hein: Genetic Dissection of ${alpha}$ ₂-Adrenoceptor Functions in Adrenergic versus Nonadrenergic Cells
Mol Pharmacol 2009 75: 1160-1170. Published online February 27, 2009; 10.1124/mol.109.054544 [Abstract] [Full Text] [PDF]

Ye Li, Yue Cui, Steven N. Hart, Curtis D. Klaassen, and Xiao-bo Zhong: Dynamic Patterns of Histone Methylation Are Associated with Ontogenic Expression of the Cyp3a Genes during Mouse Liver Maturation
Mol Pharmacol 2009 75: 1171-1179. Published online February 2, 2009; 10.1124/mol.108.052993 [Abstract] [Full Text] [PDF] [Data Supplement]

Xiu-Qi Bao and Geng-Tao Liu: Induction of Overexpression of the 27- and 70-kDa Heat Shock Proteins by Bicyclol Attenuates Concanavalin A-Induced Liver Injury through Suppression of Nuclear Factor- ${kappa}$ B in Mice
Mol Pharmacol 2009 75: 1180-1188. Published online February 2, 2009; 10.1124/mol.108.053280 [Abstract] [Full Text] [PDF]

Bin Wang, Yanmei Yang, Abdul B. Abou-Samra, and Peter A. Friedman: NHERF1 Regulates Parathyroid Hormone Receptor Desensitization: Interference with β-Arrestin Binding
Mol Pharmacol 2009 75: 1189-1197. Published online February 2, 2009; 10.1124/mol.108.054486 [Abstract] [Full Text] [PDF] [Data Supplement]

David J. Lomb, Lynette A. Desouza, James L. Franklin, and Robert S. Freeman: Prolyl Hydroxylase Inhibitors Depend on Extracellular Glucose and Hypoxia-Inducible Factor (HIF)-2 ${alpha}$ to Inhibit Cell Death Caused by Nerve Growth Factor (NGF) Deprivation: Evidence that HIF-2 ${alpha}$ Has a Role in NGF-Promoted Survival of Sympathetic Neurons
Mol Pharmacol 2009 75: 1198-1209. Published online February 9, 2009; 10.1124/mol.108.053157 [Abstract] [Full Text] [PDF]

Lan Cheng and Michael C. Sanguinetti: Niflumic Acid Alters Gating of HCN2 Pacemaker Channels by Interaction with the Outer Region of S4 Voltage Sensing Domains
Mol Pharmacol 2009 75: 1210-1221. Published online February 13, 2009; 10.1124/mol.108.054437 [Abstract] [Full Text] [PDF]

Brianna L. Goldenstein, Brian W. Nelson, Ke Xu, Elizabeth J. Luger, Jacquline A. Pribula, Jenna M. Wald, Lorraine A. O'Shea, David Weinshenker, Raelene A. Charbeneau, Xinyan Huang, Richard R. Neubig, and Van A. Doze: Regulator of G Protein Signaling Protein Suppression of G ${alpha}$ _o Protein-Mediated ${alpha}$ _2A Adrenergic Receptor Inhibition of Mouse Hippocampal CA3 Epileptiform Activity
Mol Pharmacol 2009 75: 1222-1230. Published online February 18, 2009; 10.1124/mol.108.054296 [Abstract] [Full Text] [PDF]

Rongxiu Li, Yan Zang, Changyou Li, Neil S. Patel, Jennifer R. Grandis, and Daniel E. Johnson: ABT-737 Synergizes with Chemotherapy to Kill Head and Neck Squamous Cell Carcinoma Cells via a Noxa-Mediated Pathway
Mol Pharmacol 2009 75: 1231-1239. Published online February 25, 2009; 10.1124/mol.108.052969 [Abstract] [Full Text] [PDF] [Data Supplement]

Irina Kalatskaya, Yamina A. Berchiche, Stéphanie Gravel, Brian J. Limberg, Jan S. Rosenbaum, and Nikolaus Heveker: AMD3100 Is a CXCR7 Ligand with Allosteric Agonist Properties
Mol Pharmacol 2009 75: 1240-1247. Published online March 2, 2009; 10.1124/mol.108.053389 [Abstract] [Full Text] [PDF]

Errata:

: Correction to "Capacitative Ca²⁺ Entry via Orai1 and Stromal Interacting Molecule 1 (STIM1) Regulates Adenylyl Cyclase Type 8"
Mol Pharmacol 2009 75: 1248. [Full Text] [PDF]

Cover Caption:

About the cover: Superimposition of the GluK2 agonist-binding domain in complex with the full agonist L-Glu (yellow) and partial agonist Dom (blue). See the article by Fay et al. on page 1096 of this issue.