PT - JOURNAL ARTICLE AU - DOERGE, DANIEL R. AU - MCNAMEE, MARK G. AU - INGRAHAM, LLOYD L. TI - Modification of Acetylcholine Receptor-Mediated Ion Permeability by Thiamine DP - 1979 May 01 TA - Molecular Pharmacology PG - 747--750 VI - 15 IP - 3 4099 - http://molpharm.aspetjournals.org/content/15/3/747.short 4100 - http://molpharm.aspetjournals.org/content/15/3/747.full SO - Mol Pharmacol1979 May 01; 15 AB - Thiamine has been found to be active in an acetylcholine receptor-rich postsynaptic membrane preparation from Torpedo californica electroplax by inhibiting the rate of carbamylcholine-induced acetylcholine receptor-mediated 22Na efflux. Thiamine reduces the maximal response to carbamylcholine without changing the affinity of the receptor for carbamylcholine.