RT Journal Article
SR Electronic
T1 Sodium Dependence of Transmitter Uptake at Adrenergic Nerve Terminals
JF Molecular Pharmacology
JO Mol Pharmacol
FD American Society for Pharmacology and Experimental Therapeutics
SP 360
OP 362
VO 2
IS 4
A1 IVERSEN, L. L.
A1 KRAVITZ, E. A.
YR 1966
UL http://molpharm.aspetjournals.org/content/2/4/360.abstract
AB The uptake of norepinephrine into the sympathetic innervation of the isolated rat heart was dependent on the presence of sodium ions in the external medium, but was not affected by the absence of calcium ions. The sodium dependence of norepinephrine uptake is further evidence for the view that this process is mediated by an active transport system in adrenergic nerve terminals. Similar sodium-dependent uptake processes may be present at other chemically transmitting synapses.