@article {KIESE9, author = {MANFRED KIESE}, title = {Reactions of N,N-Dimethylaniline-N-oxide with Hemoglobin}, volume = {3}, number = {1}, pages = {9--14}, year = {1967}, publisher = {American Society for Pharmacology and Experimental Therapeutics}, abstract = {N,N-Dimethylaniline-N-oxide reduces ferrihemoglobin (methemoglobin) under anaerobic conditions. In solutions of hemoglobin and N,N-dimethylaniline-N-oxide under air ferrihemoglobin is formed. Oxygen is necessary for this reaction. After a short lag phase the reaction rapidly increases in rate. Partial oxidation of the hemoglobin accelerates the reaction. Reagents which react with {\textemdash}SH groups also accelerate thue reaction. However, the "autocatalytic" course is retained after the {\textemdash}SH groups are blocked. ACKNOWLEDGMENT The author is grateful to Miss Maria Arnold and Miss Luise Richter for competent technical assistance.}, issn = {0026-895X}, URL = {https://molpharm.aspetjournals.org/content/3/1/9}, eprint = {https://molpharm.aspetjournals.org/content/3/1/9.full.pdf}, journal = {Molecular Pharmacology} }