PT - JOURNAL ARTICLE AU - PAUL BYVOET TI - Metabolic Integrity of Deoxyribonucleohistones during Enzyme Induction DP - 1967 May 01 TA - Molecular Pharmacology PG - 303--305 VI - 3 IP - 3 4099 - http://molpharm.aspetjournals.org/content/3/3/303.short 4100 - http://molpharm.aspetjournals.org/content/3/3/303.full SO - Mol Pharmacol1967 May 01; 3 AB - Previous work has shown that after individual labeling of histone and DNA of various normal and neoplastic tissues of the rat, the first-order decay rates of their respective specific activities were approximately similar. The present studies indicate that the normal turnover of histones in liver parenchymal cells is not altered during periods of alternate enzyme induction and repression resulting from dietary changes or drug injections. ACKNOWLEDGMENTS This research was supported by U. S. National Institutes of Health Grant CA-18402, CY-6506 and an American Cancer Society Institutional Grant.