TY - JOUR T1 - Multiple opioid receptors: ligand selectivity profiles and binding site signatures. JF - Molecular Pharmacology JO - Mol Pharmacol SP - 265 LP - 272 VL - 36 IS - 2 AU - A Goldstein AU - A Naidu Y1 - 1989/08/01 UR - http://molpharm.aspetjournals.org/content/36/2/265.abstract N2 - Methods are described for studying mu, delta, and kappa opioid binding sites, each without interference from the others. A large array of ligands has been characterized by ligand selectivity profiles, graphic depictions of affinities and selectivities. Binding site signatures have been derived, which uniquely describe each of the three types of sites. The mu, delta, and kappa binding sites have interesting common features and distinctive differences. ER -