TY - JOUR T1 - The Half-Life of Alanine Aminotransferase and of Total Soluble Protein in Livers of Normal and Glucocorticoid-Treated Rats JF - Molecular Pharmacology JO - Mol Pharmacol SP - 105 LP - 108 VL - 5 IS - 2 AU - YEE S. KIM Y1 - 1969/03/01 UR - http://molpharm.aspetjournals.org/content/5/2/105.abstract N2 - The half-lives of soluble protein pool and alanine aminotransferase (L-alanine: 2-oxoglutarate aminotransferase, EC 2.6.1.2) of rat liver were determined before and after prednisolone treatment by measuring the rate of disappearance of radioactivity from the labeled proteins. The half-life value of soluble protein is 4.2-4.3 days, and that of alanine aminotransferase is 3.0-3.5 days. Glucocorticoid treatment has little or no effect on the turnover rates. ACKNOWLEDGMENT The author wishes to thank Dr. H. L. Segal for critically reviewing the manuscript. ER -