PT - JOURNAL ARTICLE AU - H. F. MARLOW AU - J. C. METCALFE AU - A. S. V. BURGEN TI - The Specificity of Drug Receptors DP - 1969 Mar 01 TA - Molecular Pharmacology PG - 156--165 VI - 5 IP - 2 4099 - http://molpharm.aspetjournals.org/content/5/2/156.short 4100 - http://molpharm.aspetjournals.org/content/5/2/156.full SO - Mol Pharmacol1969 Mar 01; 5 AB - Precipitating antibodies were prepared against the determinant phenoxycholine, a nicotinic agonist. The affinity of the antibody for a wide range of agonists and antagonists related to acetylcholine was tested. The affinity constants were found to range between 3.2 x 105 and 6.9 x 103 M-1. The antibody did not discriminate between agonists and antagonists, or between drugs acting at muscarinic and nicotinic receptors.