TY - JOUR T1 - Fusion Polypeptides That Inhibit Exocytosis: Fusing Aptamer and Cell-Penetrating Peptide Technologies and Pharmacologies JF - Molecular Pharmacology JO - Mol Pharmacol SP - 980 LP - 982 DO - 10.1124/mol.105.011429 VL - 67 IS - 4 AU - Lee E. Eiden Y1 - 2005/04/01 UR - http://molpharm.aspetjournals.org/content/67/4/980.abstract N2 - Cell-penetrating peptides are amphipathic or cationic oligopeptides able to transport covalently attached cargoes across cell membranes. Peptide aptamers are polypeptide fragments of endogenous proteins that mimic and thus perturb interactions with other cellular proteins. Combining aptamer and CPP technology can generate pharmacological reagents effective in cell culture models and in vivo. ER -