PT  - JOURNAL ARTICLE
AU  - CHARLES W. HAIDLE
AU  - K. KAY WEISS
AU  - M. TIEN KUO
TI  - Release of Free Bases from Deoxyribonucleic Acid after Reaction with Bleomycin
DP  - 1972 Sep 01
TA  - Molecular Pharmacology
PG  - 531--537
VI  - 8
IP  - 5
4099  - http://molpharm.aspetjournals.org/content/8/5/531.short
4100  - http://molpharm.aspetjournals.org/content/8/5/531.full
SO  - Mol Pharmacol1972 Sep 01; 8
AB  - Labeled free bases could be detected chromatographically after reaction of deoxyribonucleic acid with high concentrations of the antibiotic bleomycin. Thymine, adenine, guanine, and cytosine were released from DNAs previously labeled in the base moiety with each of the four bases. No detectable amounts of nucleosides, nucleotides, deoxyribose, deoxyribose phosphate, or inorganic phosphate were released. ACKNOWLEDGMENTS The authors with to thank Mrs. Elsie Jackson for her excellent technical assistance, and to express appreciation to Dr. L. Daniel Inners for his assistance in the molecular weight determination.