PT  - JOURNAL ARTICLE
AU  - ROY W. BAKER
AU  - CYRUS CHOTHIA
AU  - PETER PAULING
AU  - HANS PETER WEBER
TI  - Molecular Structures of Hallucinogenic Substances: Lysergic Acid Diethylamide, Psilocybin, and 2,4,5-Trimethoxyamphetamine
DP  - 1973 Jan 01
TA  - Molecular Pharmacology
PG  - 23--32
VI  - 9
IP  - 1
4099  - http://molpharm.aspetjournals.org/content/9/1/23.short
4100  - http://molpharm.aspetjournals.org/content/9/1/23.full
SO  - Mol Pharmacol1973 Jan 01; 9
AB  - X-ray diffraction structure analyses of the hallucinogenic substances lysergic acid diethylamide o-iodobenzoate monohydrate, N,N-dimethyl-4-phosphoryloxytryptamine monoethanolate (psilocybin), and 2,4,5-trimethoxyamphetamine hydrochloride are reported. They reveal some relationships among the relative structural arrangements of possible pharmacodynamic groups of these substances. ACKNOWLEDGMENTS We thank Drs. A. Hofmann and A. T. Shulgin for crystalline samples, Dr. Trevor J. Petcher and Dr. Göran Falkenberg for useful discussion, Miss Margaret Dellow for programming assistance, Professor D. Carlström, Dr. R. Bergin, Dr. G. Falkenberg, Dr. Pamela M. Bailey, Professor K. Tomita, and Dr. G. Tsoucaris for communication of their results in advance of publication, Miss Patricia Brennan for assistance, and Mr. John Cresswell for the drawings.