PT  - JOURNAL ARTICLE
AU  - TOM LLOYD
AU  - SEYMOUR KAUFMAN
TI  - Production of Antibodies to Bovine Adrenal Tyrosine Hydroxylase: Cross-reactivity Studies with Other Pterin-Dependent Hydroxylases
DP  - 1973 Jul 01
TA  - Molecular Pharmacology
PG  - 438--444
VI  - 9
IP  - 4
4099  - http://molpharm.aspetjournals.org/content/9/4/438.short
4100  - http://molpharm.aspetjournals.org/content/9/4/438.full
SO  - Mol Pharmacol1973 Jul 01; 9
AB  - A specific antiserum to purified bovine adrenal tyrosine hydroxylase was produced in sheep. Enzyme inhibition studies and agar double-immunodiffusion reactions revealed extensive cross-reactivity between the antiserum and tyrosine hydroxylases from bovine, rat, monkey, and rabbit adrenal glands, as well as from bovine caudate and human pheochromocytoma. The specificity of the antiserum was demonstrated by the lack of inhibition of phenylalanine hydroxylase, tryptophan hydroxylase, dopamine β-hydroxylase, and tyrosinase.