RT Journal Article SR Electronic T1 UDP-Sugars as Extracellular Signaling Molecules: Cellular and Physiologic Consequences of P2Y14 Receptor Activation JF Molecular Pharmacology JO Mol Pharmacol FD American Society for Pharmacology and Experimental Therapeutics SP 151 OP 160 DO 10.1124/mol.115.098756 VO 88 IS 1 A1 Eduardo R. Lazarowski A1 T. Kendall Harden YR 2015 UL http://molpharm.aspetjournals.org/content/88/1/151.abstract AB UDP-sugars, which are indispensable for protein glycosylation reactions in cellular secretory pathways, also act as important extracellular signaling molecules. We discuss here the broadly expressed P2Y14 receptor, a G-protein–coupled receptor targeted by UDP sugars, and the increasingly diverse set of physiologic responses discovered recently functioning downstream of this receptor in many epithelia as well as in immune, inflammatory, and other cells.