PT - JOURNAL ARTICLE AU - Ana Belén Elgoyhen AU - Carlos Barajas-López TI - A Latin American Perspective on Ion Channels AID - 10.1124/mol.116.105510 DP - 2016 Sep 01 TA - Molecular Pharmacology PG - 286--287 VI - 90 IP - 3 4099 - http://molpharm.aspetjournals.org/content/90/3/286.short 4100 - http://molpharm.aspetjournals.org/content/90/3/286.full SO - Mol Pharmacol2016 Sep 01; 90 AB - Ion channels, both ligand- and voltage-gated, play fundamental roles in many physiologic processes. Alteration in ion channel function underlies numerous pathologies, including hypertension, diabetes, chronic pain, epilepsy, certain cancers, and neuromuscular diseases. In addition, an increasing number of inherited and de novo ion channel mutations have been shown to contribute to disease states. Ion channels are thus a major class of pharmacotherapeutic targets.