@article {Lazarowskimol.115.098756, author = {Eduardo R. Lazarowski and T. Kendell Harden}, title = {UDP-Sugars as Extracellular Signaling Molecules: Cellular and Physiological Consequences of P2Y14 Receptor Activation}, elocation-id = {mol.115.098756}, year = {2015}, doi = {10.1124/mol.115.098756}, publisher = {American Society for Pharmacology and Experimental Therapeutics}, abstract = {UDP-sugars, which are indispensable for protein glycosylation reactions in cellular secretory pathways, also act as important extracellular signaling molecules. We discuss here the broadly expressed P2Y14 receptor (P2Y14R), a G protein-coupled receptor (GPCR) targeted by UDP-sugars, and the increasingly diverse set of physiological responses discovered recently functioning downstream of this receptor in many epithelia as well as in immune, inflammatory, and other cells.}, issn = {0026-895X}, URL = {https://molpharm.aspetjournals.org/content/early/2015/03/31/mol.115.098756}, eprint = {https://molpharm.aspetjournals.org/content/early/2015/03/31/mol.115.098756.full.pdf}, journal = {Molecular Pharmacology} }