TY - JOUR T1 - Corticotropin-releasing factor receptors and their interacting proteins: functional consequences JF - Molecular Pharmacology JO - Mol Pharmacol DO - 10.1124/mol.116.104927 SP - mol.116.104927 AU - Paula G Slater AU - Hector E Yarur AU - Katia Gysling Y1 - 2016/01/01 UR - http://molpharm.aspetjournals.org/content/early/2016/09/09/mol.116.104927.abstract N2 - The corticotropin-releasing factor (CRF) system is involved in stress and addiction as well as in anxiety disorders such as depression. CRF acts through type-1 and type-2 CRF receptors. Both types of receptors are G-protein coupled receptors (GPCRs). The purpose of this minireview is to highlight recent advances on the interactions of CRF receptors with other GPCRs and non-GPCR proteins, and their associated functional consequences. The better understanding of these interactions may generate new pharmacological alternatives for the treatment of addiction and stress-related disorders. ER -