TY - JOUR T1 - Corticotropin-Releasing Factor Receptors and Their Interacting Proteins: Functional Consequences JF - Molecular Pharmacology JO - Mol Pharmacol SP - 627 LP - 632 DO - 10.1124/mol.116.104927 VL - 90 IS - 5 AU - Paula G. Slater AU - Hector E. Yarur AU - Katia Gysling Y1 - 2016/11/01 UR - http://molpharm.aspetjournals.org/content/90/5/627.abstract N2 - The corticotropin-releasing factor (CRF) system, which is involved in stress, addiction, and anxiety disorders such as depression, acts through G-protein–coupled receptors (GPCRs) known as type-1 and type-2 CRF receptors. The purpose of this review is to highlight recent advances in the interactions of CRF receptors with other GPCRs and non-GPCR proteins and their associated functional consequences. A better understanding of these interactions may generate new pharmacological alternatives for the treatment of addiction and stress-related disorders. ER -