Model variables
| Description | |
|---|---|
| Cell-level model variables | |
| N | Cell density, number/liter |
| R s | Cell-surface receptors, number/cell |
| C s | Cell-surface complexes, number/cell |
| L i | Intracellular ligand, M |
| R i | Intracellular receptors, number/cell |
| C i | Intracellular complexes, number/cell |
| L | Extracellular ligand (or main compartment ligand), M |
| L d | Degraded ligand, number/cell |
| Additional PK/PD model variables | |
| L 4 | Ligand in second compartment, M |
| n 1 | Bisegmental absorption site 1 from subcutaneous dose, moles |
| n 2 | Bisegmental absorption site 2 from subcutaneous dose, moles |