IC50 values for inhibitors of CYP26A1
IC50 values were obtained from the fits of the data shown in Figs. 5 and 6.
| Compound | IC50 or Kd (S.E.) |
|---|---|
| μM | |
| R116010 | 0.0043 (0.0007) |
| R115866 | 0.0051 (0.0008) |
| CD1530 | 0.53 (1.9) |
| Ketoconazole | 0.55 (1.3) |
| L-165,041 | 1.7 (1.6) |
| Liarozole | 2.1 (1.1) |
| CS5 | 2.6 (1.3)a |
| TTNPB | 3.7 (1.6) |
| Rosiglitazone | 4.2 (1.3) |
| Pioglitazone | 8.6 (1.2) |
↵a The IC50 value is determined as 50% inhibition of the maximum 71% inhibition observed.