Doubling time and AGT activity of PES43 and PES47 clones expressing control (pBABE) or DN-hTERT virus
| Cell Lines | Doubling Time | P | AGT | P |
|---|---|---|---|---|
| h | fmol/mg | |||
| PES43 | 42 ± 0.5 | 119 ± 16 | ||
| PES43-pBABE-1 | 41 ± 1 | N.S. | 116 ± 3 | N.S. |
| PES43-pBABE-2 | 43 ± 3 | N.S. | 104 ± 0.1 | N.S. |
| PES43-DN-1 | 70 ± 2 | = 0.0001 | 100 ± 13 | N.S. |
| PES43-DN-2 | 72 ± 2 | <0.0001 | 90 ± 15 | N.S. |
| PES47 | 46 ± 1 | 114 ± 11 | ||
| PES47-pBABE-1 | 45 ± 1 | N.S. | 89 ± 4 | N.S. |
| PES47-pBABE-2 | 43 ± 1 | N.S. | 97 ± 3 | N.S. |
| PES47-DN-1 | 74 ± 1 | <0.0001 | 99 ± 1 | N.S. |
| PES47-DN-2 | 70 ± 2 | = 0.0001 | 98 ± 2 | N.S. |
| PES47-DN-3 | 71 ± 2 | <0.0001 | 86 ± 4 | N.S. |
Statistical analysis was performed according to Student's ttest.
N.S., not statistically significant.