Effect of deoxycytidine analog triphosphates on dCMP deaminase activity in the absence of dCTP
| Triphosphate | Relative Rate (20 μM) |
|---|---|
| % | |
| dCTP | 100 |
| dFdCTP | <0.1 |
| AraCTP | <0.1 |
| ddCTP | <0.1 |
| l-ddCTP | <0.1 |
| l-SddCTP | <0.1 |
| l-FSddCTP | <0.1 |
| l-Fd4CTP | <0.1 |
| l-FSddCTP | <0.1 |
dCMP concentration was 50 μM; 0.9 U of enzyme was used for every reaction. The rate was normalized as the percentage of dCTP sample. Values are presented as mean of three independent experiments.