XMPPCH2P | XMPPNHP | |
---|---|---|
μm | ||
IC50 | 132 ± 34 | 202 ± 85 |
Apparent KD | 44 ± 11 | 67 ± 28 |
Experiments as shown in Fig. 2 and 3 were performed to determine the IC50 value. The apparent KD value for each nucleotide was calculated from IC50 =KD (1 + [XDP]/EC50(XDP)) (20), where [XDP] = 100 μm and the estimated EC50(XDP) = 50 μm (9). Results are averages of four experiments.